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    Optical MRI device
    3.
    发明授权
    Optical MRI device 有权

    公开(公告)号：US09746419B2

    公开(公告)日：2017-08-29

    申请号：US12662815

    申请日：2010-05-05

    申请人： Florian Stuker ,  Katerina Dikaiou ,  Christof Baltes ,  Markus Rudin

    发明人： Florian Stuker ,  Katerina Dikaiou ,  Christof Baltes ,  Markus Rudin

    IPC分类号： A61B5/05 ,  G01N21/64 ,  A61B5/00 ,  G01N21/47

    CPC分类号： G01N21/6456 ,  A61B5/0035 ,  A61B5/0042 ,  A61B5/0073 ,  A61B5/0077 ,  A61B2503/40 ,  G01N21/4795

    摘要： A dual modality imaging apparatus, comprising a magnetic resonance imaging (=MRI) system and a fluorescence molecular tomography (=FMT) system, for investigating a sample (42) located at a sample position (10), wherein the MRI system comprises a magnet (9) with a room temperature bore (8), with the sample position (10) located within the bore (8), and wherein the FMT system comprises means for directing a light beam (12, 17; 30) towards the sample position (10), and a position-sensitive detector (37) for collecting fluorescence light from the sample (42), is characterized in that the position-sensitive detector (37) is located within the bore (8), wherein at least part of the sample (42) is imaged onto the position-sensitive detector (37), and that the means for directing the light beam (12, 17; 30) comprise a focusing device for focusing the light beam (12, 17; 30) into a focal spot (41) on the sample (42), and a scanning device for scanning the focal spot (41) on the sample (42). The apparatus is simple in design and versatile in application, and in particular imposes less limitations on the maximum number of source/detector pairs during FMT imaging, thus allowing a better FMT image resolution.

    Optical MRI device
    5.
    发明申请
    Optical MRI device 有权
    光学MRI装置

    公开(公告)号：US20100292563A1

    公开(公告)日：2010-11-18

    申请号：US12662815

    申请日：2010-05-05

    申请人： Florian Stuker ,  Katerina Dikaiou ,  Christof Baltes ,  Markus Rudin

    发明人： Florian Stuker ,  Katerina Dikaiou ,  Christof Baltes ,  Markus Rudin

    IPC分类号： A61B5/05 ,  A61B6/00

    CPC分类号： G01N21/6456 ,  A61B5/0035 ,  A61B5/0042 ,  A61B5/0073 ,  A61B5/0077 ,  A61B2503/40 ,  G01N21/4795

    摘要： A dual modality imaging apparatus, comprising a magnetic resonance imaging (=MRI) system and a fluorescence molecular tomography (=FMT) system, for investigating a sample (42) located at a sample position (10), wherein the MRI system comprises a magnet (9) with a room temperature bore (8), with the sample position (10) located within the bore (8), and wherein the FMT system comprises means for directing a light beam (12, 17; 30) towards the sample position (10), and a position-sensitive detector (37) for collecting fluorescence light from the sample (42), is characterized in that the position-sensitive detector (37) is located within the bore (8), wherein at least part of the sample (42) is imaged onto the position-sensitive detector (37), and that the means for directing the light beam (12, 17; 30) comprise a focusing device for focusing the light beam (12, 17; 30) into a focal spot (41) on the sample (42), and a scanning device for scanning the focal spot (41) on the sample (42). The apparatus is simple in design and versatile in application, and in particular imposes less limitations on the maximum number of source/detector pairs during FMT imaging, thus allowing a better FMT image resolution.

    摘要翻译： 一种双模式成像设备，包括用于调查位于样本位置（10）的样本（42）的磁共振成像（= MRI）系统和荧光分子断层摄影（= FMT）系统，其中所述MRI系统包括磁体 （9）具有室温孔（8），其中样品位置（10）位于孔（8）内，并且其中FMT系统包括用于将光束（12,17; 30）引向样品位置的装置 （10）和用于从样品（42）收集荧光的位置敏感检测器（37）的特征在于位置敏感检测器（37）位于孔（8）内，其中至少部分 样品（42）被成像到位置敏感检测器（37）上，并且用于引导光束（12,17; 30）的装置包括聚焦装置，用于将光束（12,17; 30）聚焦到 样品（42）上的焦点（41）和用于扫描样品（42）上的焦点（41）的扫描装置。 该设备设计简单，应用广泛，特别是在FMT成像期间对源/检测器对的最大数量的限制较少，因此允许更好的FMT图像分辨率。