-
公开(公告)号：US08765113B2
公开(公告)日：2014-07-01
申请号：US13534164
申请日：2012-06-27
Applicant: Jan J. Lewandowski , Yubaio Liu
Inventor： Jan J. Lewandowski , Yubaio Liu
IPC: A01P1/00 , A01N37/46 , C08F26/02 , C08F8/30 , A61L27/54 , A61L29/16 , A61L31/16 , A61L33/12 , A61L28/00
CPC classification number: A61L33/12 , A61L27/54 , A61L28/0038 , A61L29/16 , A61L31/16 , A61L2300/25 , A61L2300/404
Abstract: A comb-like surfactant polymer for changing the surface properties of biomaterials is described. The surfactant polymer comprises a polymeric backbone of repeating monomeric units having functional groups for chemically attaching to side chains, a plurality of hydrophobic side chains attached to the backbone via the functional groups and a plurality of hydrophilic side chains chemically attached via functional groups to the polymeric backbone. The hydrophilic side chains providing anti-thrombogenic properties to the surfactant. An antimicrobial agent selectively attached to some hydrophilic side chains thereby providing additional antimicrobial properties to the surfactant. The surfactant polymer may be applied to the surface of medical devices to reduce the surfaces thrombogenicity and decrease the number of microorganisms on the surface.
Abstract translation: 描述了用于改变生物材料的表面性质的梳状表面活性剂聚合物。 表面活性剂聚合物包含具有用于化学连接到侧链的具有官能团的重复单体单元的聚合物主链，经由官能团连接到主链上的多个疏水侧链和通过官能团化学连接到聚合物上的多个亲水侧链 骨干。 亲水侧链为表面活性剂提供抗血栓形成性质。 选择性地连接到一些亲水侧链的抗微生物剂，从而为表面活性剂提供额外的抗微生物性质。 可以将表面活性剂聚合物施加到医疗装置的表面以降低表面血栓形成并减少表面上的微生物数量。
-
公开(公告)号：US5304203A
公开(公告)日：1994-04-19
申请号：US963718
申请日：1992-10-20
Applicant: Amin El-Mallawany , Jan J. Lewandowski
Inventor： Amin El-Mallawany , Jan J. Lewandowski
CPC classification number: A61B17/29 , A61B10/06 , A61B2017/2837 , A61B2017/2931
Abstract: Tissue extracting forceps are disclosed which have been designed for use in laparoscopic surgery. The forceps firmly grasp tissue or organs which are to be moved or removed during the procedure. The grasping members of the forceps are aligned such that fragmentation damage to the grasped tissue is minimized. The mechanical layout of the forceps allows the user to manipulate the working end for a distance, so that the user's fingers do not get in the way of the surgical procedure. The working end of the forceps is adaptable to be used with grasping members of different shapes, or with disposable cutting instruments. Any of these working ends may be incorporated in the same overall mechanical design.
Abstract translation: 公开了已经设计用于腹腔镜手术的组织提取镊子。 镊子牢牢抓住在手术过程中要移动或移除的组织或器官。 镊子的把持构件对准，使得被抓取的组织的碎裂损伤最小化。 镊子的机械布局允许使用者操作一段距离的工作端，使得使用者的手指不妨碍外科手术。 镊子的工作端适用于不同形状的抓握部件或一次性切割工具。 这些工作端中的任何一个都可以结合在相同的整体机械设计中。
-
公开(公告)号：US20070261494A1
公开(公告)日：2007-11-15
申请号：US11696036
申请日：2007-04-03
Applicant: William R. Fuller , Daniel N. Kelsch , Jan J. Lewandowski , Grazyna Palczewska , Alexander K. Smith
Inventor： William R. Fuller , Daniel N. Kelsch , Jan J. Lewandowski , Grazyna Palczewska , Alexander K. Smith
IPC: G01N29/04
Abstract: Detection apparatus can include a positioning device with a wall including a substantially conical inner surface and a detection device configured to send and receive signals and move along the conical inner surface. Detection apparatus are also provided that comprise a positioning device and an end portion with an image port, a light device, and a detection device configured to send and receive signals. Ultrasonic transducer devices are also provided with a transducer material layer, a contact plating layer including a convex portion with an array of transducer elements, an acoustic matching layer, and a top plating layer.
Abstract translation: 检测装置可以包括具有包括基本上圆锥形内表面的壁的定位装置和被配置为发送和接收信号并沿着锥形内表面移动的检测装置。 还提供了检测装置，其包括定位装置和具有图像端口的端部，光装置和被配置为发送和接收信号的检测装置。 超声波换能器装置还设置有换能器材料层，接触镀层，包括具有换能器元件阵列的凸部，声匹配层和顶镀层。
-
公开(公告)号：US06558529B1
公开(公告)日：2003-05-06
申请号：US09499421
申请日：2000-02-07
Applicant: Iain F. McVey , Brian J. DeSantis , Jan J. Lewandowski , Karen L. Thomas , Brian E. Schindly
Inventor： Iain F. McVey , Brian J. DeSantis , Jan J. Lewandowski , Karen L. Thomas , Brian E. Schindly
IPC: G01N2726
CPC classification number: G01N27/4045 , G01N27/49
Abstract: An electrochemical sensor (A, A′) is specific for the detection of peroxyacetic acid in a solution which also contains hydrogen peroxide. A potential is applied between a reference electrode (120, 120′) and a working electrode (118, 118′). A read voltage (FIG. 7) is selectively pulsed across a counter electrode (122, 122′) and the working electrode. The current flowing between the working electrode and the counter electrode is dependent on the peroxyacetic acid concentration in the solution (FIG. 6). By careful selection of the read voltage, the contribution of hydrogen peroxide to the current flow is virtually negligible. The sensor effectively measures peroxyacetic acid concentrations in the range generally employed in sterilization and disinfection baths (100-3000 ppm.).
-
公开(公告)号：USD389964S
公开(公告)日：1998-01-27
申请号：US64024
申请日：1996-12-20
Applicant: Jan J. Lewandowski , Nick A. Deeter , John A. Engelhardt
Designer： Jan J. Lewandowski , Nick A. Deeter , John A. Engelhardt
-
Patent Agency Ranking
公开(公告)号：US20120328556A1
公开(公告)日：2012-12-27
申请号：US13534164
申请日：2012-06-27
Applicant: Jan J. Lewandowski , Yubiao Liu
Inventor： Jan J. Lewandowski , Yubiao Liu
CPC classification number: A61L33/12 , A61L27/54 , A61L28/0038 , A61L29/16 , A61L31/16 , A61L2300/25 , A61L2300/404
Abstract: A comb-like surfactant polymer for changing the surface properties of biomaterials is described. The surfactant polymer comprises a polymeric backbone of repeating monomeric units having functional groups for chemically attaching to side chains, a plurality of hydrophobic side chains attached to the backbone via the functional groups and a plurality of hydrophilic side chains chemically attached via functional groups to the polymeric backbone. The hydrophilic side chains providing anti-thrombogenic properties to the surfactant. An antimicrobial agent selectively attached to some hydrophilic side chains thereby providing additional antimicrobial properties to the surfactant. The surfactant polymer may be applied to the surface of medical devices to reduce the surfaces thrombogenicity and decrease the number of microorganisms on the surface.
Abstract translation: 描述了用于改变生物材料的表面性质的梳状表面活性剂聚合物。 表面活性剂聚合物包含具有用于化学连接到侧链的具有官能团的重复单体单元的聚合物主链，经由官能团连接到主链上的多个疏水侧链和通过官能团化学连接到聚合物上的多个亲水侧链 骨干。 亲水侧链为表面活性剂提供抗血栓形成性质。 选择性地连接到一些亲水侧链的抗微生物剂，从而为表面活性剂提供额外的抗微生物性质。 可以将表面活性剂聚合物施加到医疗装置的表面以降低表面血栓形成并减少表面上的微生物数量。
-
公开(公告)号：US09125969B2
公开(公告)日：2015-09-08
申请号：US13422150
申请日：2012-03-16
Applicant: Jan J. Lewandowski , Yubiao Liu , Roger Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
Inventor： Jan J. Lewandowski , Yubiao Liu , Roger Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
IPC: A61L27/34 , A61L29/08 , A61L31/10 , A61L33/00 , A61L33/08 , A61L33/12 , C08B37/02 , C08B37/00 , C08F8/00
CPC classification number: A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0017 , A61L33/08 , A61L33/128 , C08B37/0021 , C08B37/0078 , C08F8/00 , C08L101/00 , C08F26/02 , C08F16/06
Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
Abstract translation: 提供了梳状，用于改变生物材料表面性质的表面活性剂聚合物。 这种表面活性剂聚合物包含具有用于与侧链偶联的官能团的重复单体单元的聚合物主链，经由官能团与主链连接的多个疏水侧链，以及通过官能团连接至所述骨架的多个亲水侧链 。 还提供了涂有表面活性剂聚合物的医疗装置。 表面活性剂聚合物可用于降低医疗装置的血栓形成性质，包封和细菌定植。
-
8.发明授权Mechanical stability of the biomimetic coating by cross linking of surfactant polymer 有权通过表面活性剂聚合物的交联，仿生涂层的机械稳定性公开(公告)号：US08945664B1
公开(公告)日：2015-02-03
申请号：US13283763
申请日：2011-10-28
Applicant: Jan J. Lewandowski , Yubiao Liu
Inventor： Jan J. Lewandowski , Yubiao Liu
CPC classification number: C08F220/58 , A61L29/085 , A61L31/10 , C08B37/0021 , C09D4/06 , C08L39/02 , C08L5/02
Abstract: A biomimetic surfactant polymer modified with various crosslinking embodiments is described. The crosslinking embodiments provide a biomimetic surfactant coating that is designed to resist cracking, scratching, spalling and chemical dissolution. The crosslinking embodiments comprise the use of various hydrophilic and hydrophobic functional groups. The modified biomimetic surfactant adheres to different substrate surfaces, particularly the surfaces of medical devices.
Abstract translation: 描述了用各种交联实施方案改性的仿生表面活性剂聚合物。 交联实施方案提供了被设计成可以抗开裂，划伤，剥落和化学溶解的仿生表面活性剂涂层。 交联实施方案包括使用各种亲水和疏水官能团。 修饰的仿生表面活性剂粘附到不同的基底表面，特别是医疗装置的表面。
-
公开(公告)号：US06592730B1
公开(公告)日：2003-07-15
申请号：US09499479
申请日：2000-02-07
Applicant: Daniel N. Kelsch , Iain F. McVey , Jan J. Lewandowski
Inventor： Daniel N. Kelsch , Iain F. McVey , Jan J. Lewandowski
IPC: G01N2726
CPC classification number: A61L2/186 , A61L2202/11
Abstract: An electrochemical analysis system includes a chamber (34) that defines a fluid receiving reservoir therein. A working electrode (40), a reference electrode (42), and a counter electrode (44) is mounted to the chamber. An electrochemical analysis circuit (38) applies appropriate voltages to the electrodes and reads appropriate currents from the electrodes to provide an indication of the peroxyacetic acid concentration in a sample. The working electrode includes a glassy carbon rod (60) which is surrounded by a compressible polymeric sleeve (64) and a metal sleeve (66). One end of the metal sleeve is swaged (68) to form a fluid tight compression seal with the insulating sleeve and the glassy carbon rod. An electrically conductive thermal extension joint between the glassy carbon rod and an electrically conductive rod (70) includes a bore (72) in the conductive rod in which the glassy carbon rod is slidably received and a compressed spring (74) in the bore.
Abstract translation: 电化学分析系统包括在其中限定流体接收容器的腔室（34）。 工作电极（40），参比电极（42）和对电极（44）安装在腔室上。 电化学分析电路（38）对电极施加适当的电压并从电极读取合适的电流以提供样品中过氧乙酸浓度的指示。 工作电极包括由可压缩聚合物套筒（64）和金属套筒（66）包围的玻璃碳棒（60）。 金属套筒的一端被锻压（68）以与绝缘套管和玻璃碳棒形成流体密封的压缩密封。 玻璃碳棒和导电棒（70）之间的导电热延伸接头包括导电棒中的孔（72），玻璃碳棒可滑动地容纳在孔中，孔中的压缩弹簧（74）。
-
公开(公告)号：USD390668S
公开(公告)日：1998-02-10
申请号：US64180
申请日：1996-12-23
Applicant: Jan J. Lewandowski , Nick A. Deeter
Designer： Jan J. Lewandowski , Nick A. Deeter
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.014 seconds)
