公开(公告)号：US20230340155A1

公开(公告)日：2023-10-26

申请号：US18331280

申请日：2023-06-08

Applicant: Janssen Biotech, Inc.

Inventor： Qiang Chen ,  Suzanne Cole ,  Karen Duffy ,  Yanxia Guo ,  Debra Gardner ,  Damon Hamel ,  Shannon Hitchcock ,  Ann Lacombe ,  Jinquan Luo ,  Ravi Malaviya ,  Yevgeniya Orlovsky ,  Pejman Soroosh ,  Melissa Swiecki ,  Deepti Wilkinson

IPC: C07K16/40 ,  C07K16/28 ,  A61P37/06 ,  C07K16/18 ,  C07K16/06 ,  A61K39/395 ,  C12N15/00

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61P37/06 ,  C07K16/065 ,  C07K16/18 ,  C07K16/2818 ,  C12N15/00 ,  A61K2039/57

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

公开(公告)号：US20210102000A1

公开(公告)日：2021-04-08

申请号：US17125263

申请日：2020-12-17

Applicant: Janssen Biotech, Inc.

Inventor： Qiang Chen ,  Suzanne Cole ,  Karen Duffy ,  Yanxia Guo ,  Debra Gardner ,  Damon Hamel ,  Shannon Hitchcock ,  Ann Lacombe ,  Jinquan Luo ,  Ravi Malaviya ,  Yevgeniya Orlovsky ,  Pejman Soroosh ,  Melissa Swiecki ,  Deepti Wilkinson

IPC: C07K16/40 ,  A61P37/06 ,  C07K16/06 ,  A61K39/395 ,  C07K16/18 ,  C07K16/28

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

公开(公告)号：US12162951B2

公开(公告)日：2024-12-10

申请号：US17376830

申请日：2021-07-15

Applicant: Janssen Biotech, Inc.

Inventor： Zemeda Ainekulu ,  Qiang Chen ,  Ellen Chi ,  Wilson Edwards ,  Matt Husovsky ,  Ann Lacombe ,  Quynh Nguyen ,  Paul H. Kim ,  H. Mimi Zhou ,  John T. Lee

IPC: G01N33/53 ,  C07H21/04 ,  C07K1/22 ,  C07K16/42 ,  C12N5/02 ,  C12N15/00 ,  C12P21/06 ,  G01N33/68

Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a KL2B413 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include KL2B413.

公开(公告)号：US10995149B2

公开(公告)日：2021-05-04

申请号：US15997148

申请日：2018-06-04

Applicant: Janssen Biotech, Inc.

Inventor： Qiang Chen ,  Suzanne Cole ,  Karen Duffy ,  Yanxia Guo ,  Debra Gardner ,  Damon Hamel ,  Shannon Hitchcock ,  Ann Lacombe ,  Jinquan Luo ,  Ravi Malaviya ,  Yevgeniya Orlovsky ,  Pejman Soroosh ,  Melissa Swiecki ,  Deepti Wilkinson

IPC: C07K16/40 ,  A61P37/06 ,  C07K16/06 ,  A61K39/395 ,  C07K16/18 ,  C07K16/28 ,  A61K39/00

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

公开(公告)号：US12030937B2

公开(公告)日：2024-07-09

申请号：US17376874

申请日：2021-07-15

Applicant: Janssen Biotech, Inc.

Inventor： Ellen Chi ,  Wilson Edwards ,  Matt Husovsky ,  Ann Lacombe ,  Christian Martinez ,  H. Mimi Zhou ,  John T. Lee

IPC: C07K16/28 ,  G01N33/50

CPC classification number: C07K16/28 ,  G01N33/5005 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/565 ,  C07K2317/567 ,  G01N2333/705

Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a GP5B83 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include GP5B83.

公开(公告)号：US11746161B2

公开(公告)日：2023-09-05

申请号：US17125263

申请日：2020-12-17

Applicant: Janssen Biotech, Inc.

Inventor： Qiang Chen ,  Suzanne Cole ,  Karen Duffy ,  Yanxia Guo ,  Debra Gardner ,  Damon Hamel ,  Shannon Hitchcock ,  Ann Lacombe ,  Jinquan Luo ,  Ravi Malaviya ,  Yevgeniya Orlovsky ,  Pejman Soroosh ,  Melissa Swiecki ,  Deepti Wilkinson

IPC: C07K16/40 ,  A61P37/06 ,  C07K16/06 ,  A61K39/395 ,  C07K16/18 ,  C07K16/28 ,  A61K39/00 ,  C12N15/00

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61P37/06 ,  C07K16/065 ,  C07K16/18 ,  C07K16/2818 ,  C12N15/00 ,  A61K2039/505 ,  A61K2039/57 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/75 ,  C07K2317/76 ,  C07K2317/92

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

公开(公告)号：US20180355061A1

公开(公告)日：2018-12-13

申请号：US15997148

申请日：2018-06-04

Applicant: Janssen Biotech, Inc.

Inventor： Qiang Chen ,  Suzanne Cole ,  Karen Duffy ,  Yanxia Guo ,  Debra Gardner ,  Damon Hamel ,  Shannon Hitchcock ,  Ann Lacombe ,  Jinquan Luo ,  Ravi Malaviya ,  Yavegniya Orlovsky ,  Pejman Soroosh ,  Melissa Swiecki ,  Deepti Wilkinson

IPC: C07K16/40 ,  A61P37/06 ,  C07K16/18 ,  C07K16/06 ,  A61K39/395

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61K2039/57 ,  A61P37/06 ,  C07K16/065 ,  C07K16/18

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.