公开(公告)号：US20240124583A1

公开(公告)日：2024-04-18

申请号：US18397711

申请日：2023-12-27

Applicant: Janssen Biotech, Inc.

Inventor： Rajkumar Ganesan ,  John Lee ,  Jinquan Luo ,  Theresa McDevitt ,  Fei Shen ,  Degang Song ,  Raymond Brittingham ,  Sathyadevi Venkataramani ,  Sanjaya Singh ,  Yonghong Zhao ,  Fang Yi ,  Sherry Lynn LaPorte

IPC: C07K16/28 ,  C07K16/34

CPC classification number: C07K16/2809 ,  C07K16/34 ,  C07K2317/14 ,  C07K2317/31 ,  C07K2317/565

Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.