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公开(公告)号:US20050203006A1
公开(公告)日:2005-09-15
申请号:US11121851
申请日:2005-05-04
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan Watson , Yan Zhang
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译: 本发明涉及新型脂肽化合物。 本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。 本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。
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公开(公告)号:US07408025B2
公开(公告)日:2008-08-05
申请号:US09737908
申请日:2000-12-15
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号: C07K7/50
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
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公开(公告)号:US20090011977A1
公开(公告)日:2009-01-08
申请号:US12163225
申请日:2008-06-27
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译: 本发明涉及新型脂肽化合物。 本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。 本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。
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公开(公告)号:US07335725B2
公开(公告)日:2008-02-26
申请号:US11121851
申请日:2005-05-04
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号: C07K7/50
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译: 本发明涉及新型脂肽化合物。 本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。 本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。
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公开(公告)号:US20080287347A1
公开(公告)日:2008-11-20
申请号:US12163299
申请日:2008-06-27
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译: 本发明涉及新型脂肽化合物。 本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。 本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。
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公开(公告)号:US06911525B2
公开(公告)日:2005-06-28
申请号:US09738742
申请日:2000-12-15
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译: 本发明涉及新型脂肽化合物。 本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。 本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。
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公开(公告)号:US06794490B2
公开(公告)日:2004-09-21
申请号:US09739535
申请日:2000-12-15
申请人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人: Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号: A61K3812
摘要: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译: 本发明涉及新型脂肽化合物。 本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。 本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。
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公开(公告)号:US20180246004A1
公开(公告)日:2018-08-30
申请号:US15443658
申请日:2017-02-27
申请人: Yan Zhang
发明人: Yan Zhang
CPC分类号: G01M3/243 , G01M3/2815
摘要: Four (4) methods and systems that utilize these methods are claimed in the present invention for intelligently detecting pipeline small leaks, thefts, and their details.In the Energy Flow Line Method, the measured flow data at both ends of the pipeline will be monitored and analyzed. If flow changes that meet the criteria are identified, a leak or a theft is detected. The energy wave front speed is introduced and the unsteady flow mathematical model of the subject pipeline is utilized to calculate leak details.In the Filtered Pressure Waves Method, the measured pressure data at both ends of the pipeline will be monitored and analyzed. After filtering, only those pressure waves that are not originated at the ends of the pipeline will be selected as candidates. For each computation step, consecutively apply the 2 travelling time windows template 1 and template 2 to those candidates, and process those candidates within each window. Leaks, thefts and their details (except for leaked amount) can be obtained if the detected leak locations meet the criteria, even when the fluid is stagnant for some time.The Enhanced Filtered Pressure Waves Method, as the name suggests, is the enhanced version of the Filtered Pressure Waves Method if the fluid is not stagnant for some time. The essential part of the Energy Flow Line Method is used to extend the function not only to provide the leaked amount, but also to verify the leak and the leak location in order to avoid sending false alarms. The measured flow data at the outlet end of the pipeline is also monitored and the unsteady flow mathematical model of the subject pipeline is utilized. If the fluid is stagnant for some time, the leaked amount will be calculated without measured data to be compared. The estimated leak location will be provided with a search range.In the Mutual Confirmation Method, essential parts of the above 3 methods are utilized to extend the capability and to confirm each finding. If any result that contradicts the solution is identified, find a new one that fits. By providing the solution that is mutually confirmed with 2 sets of leak details, sending false alarms can be avoided. This method is particularly developed to solve some issues in the real time monitoring applications, especially in SCADA environments, to have shorter calculation time. The unsteady flow mathematical model of the subject pipeline is indispensable for this method. If the fluid is stagnant for some time, the leaked amount will be calculated without measured data to be compared. Also the estimated leak location will be provided with a search range.The present invention is suitable for most pipeline applications, including very long pipelines (for instance, over 200 km), existing pipelines (with min or no modification on existing sensor groups), and pipelines that are shut for some time (excluding using the Energy Flow Line Method), and easily used as a cross checking tool to other pipelines and other online leak detection systems. The fluids in pipelines can be gases, liquids, and multi-phase fluids.
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公开(公告)号:US09780291B2
公开(公告)日:2017-10-03
申请号:US14344179
申请日:2012-09-13
申请人: Zhong L. Wang , Xinyu Xue , Yan Zhang , Sihong Wang
发明人: Zhong L. Wang , Xinyu Xue , Yan Zhang , Sihong Wang
IPC分类号: H01M14/00 , H01L41/113 , H01M4/505 , H01M4/525 , H01G11/06 , H01G11/58 , H01M10/0525 , H01M10/42 , H01M10/46 , H01M10/0568 , H01M10/0569
CPC分类号: H01L41/113 , H01G11/06 , H01G11/58 , H01M4/505 , H01M4/525 , H01M10/0525 , H01M10/0568 , H01M10/0569 , H01M10/425 , H01M10/46 , H01M14/00
摘要: A self-charging power pack (300) includes a cathode (312) and an anode (310) that is spaced apart from the cathode (312). An electrolyte (318) is disposed between the anode (310) and the cathode (312). A piezoelectric ion transport layer (322) is disposed between the anode (310) and the cathode (312). The piezoelectric ion transport layer (322) has a piezoelectric property that generates a piezoelectric field when a mechanical force is applied thereto. The piezoelectric field causes transportation of ions in the electrolyte (318) through the piezoelectric ion transport layer (322) towards the anode (310).
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