APOCRINE CELL LINE
    9.
    发明申请
    APOCRINE CELL LINE 审中-公开
    APOCRINE细胞系

    公开(公告)号:US20100184213A1

    公开(公告)日:2010-07-22

    申请号:US12532438

    申请日:2008-02-22

    IPC分类号: C12N5/071

    CPC分类号: C12N5/0633 G01N33/5044

    摘要: An apocrine cell line is obtained by the steps of isolating an apocrine cell from primary tissue, culturing the isolated cell in a first culture medium, removing unattached cells from the first culture medium and transferring said unattached cells to a second culture medium comprising an effective concentration of a phorbol ester, and thereby establishing an apocrine cell line exhibiting long-term proliferation capability, which after many cultures is indicative of indefinite proliferation.

    摘要翻译: 通过以下步骤获得顶分泌细胞系:从初级组织分离顶分泌细胞,在第一培养基中培养分离的细胞,从第一培养基中除去未附着的细胞,并将所述未附着的细胞转移到包含有效浓度的第二培养基 的佛波酯,从而建立显示长期增殖能力的顶分泌细胞系,其在许多培养物指示无限增殖之后。

    Antiperspirant and deodorant products and methods for their use
    10.
    发明授权
    Antiperspirant and deodorant products and methods for their use 有权
    止汗和除臭产品及其使用方法

    公开(公告)号:US06632422B2

    公开(公告)日:2003-10-14

    申请号:US09920779

    申请日:2001-08-02

    IPC分类号: A61K732

    摘要: A new method for the inhibition of human sweating and body malodour is described. An agent capable of blocking calcium channels in the secretory coil cells of human sweat glands is topically applied; on reaching the secretory coil cells, the action of this agent results in reduced sweat production. Preferred agents are natural plant extracts. The transport of the agent to the secretory coil is preferably enhanced in some way, for example by iontophoresis or the use of a skin penetration enhancer. Antiperspirant products comprising a calcium channel blocking agent and a pore-blocking antiperspirant active are also claimed.

    摘要翻译: 描述了抑制人的出汗和身体恶臭的新方法。 局部应用能阻断人汗腺分泌线圈细胞钙通道的药剂; 在达到分泌线圈细胞时,该试剂的作用导致汗液产生减少。 优选的药剂是天然植物提取物。 药剂向分泌线圈的转运优选以某种方式增强,例如通过离子电渗疗法或使用皮肤渗透增强剂。 还要求保护包含钙通道阻断剂和阻气止汗活性物质的止汗剂产品。