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公开(公告)号：US07753917B2
公开(公告)日：2010-07-13
申请号：US10814018
申请日：2004-03-31
IPC分类号： A61F11/00
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/22035 , A61B2017/22038 , A61B2017/2215 , A61B2090/08021 , A61F2/95
摘要： A medical grasping device (10) for vascular use, having an outer sheath (12), an elongate control member (50) extending within an outer sheath (12) to a distal tip section (54), and a proximal control assembly (22) including an actuation section (24) joined to the elongate control member (50). Adjacent to the distal tip section (54) is a grasping portion (70, 70′) that is extendable from the outer sheath (12) to create loops (74, 74′) for grasping a target object (T) for repositioning within the vascular system, or for removal from the patient, with loops being retractable into the outer sheath to hold the target object against the device (10) during movement of the device. Elongate control member (50) is preferably a cannula or tube having a lumen (58) extending completely therethrough for placement over a guide wire (28) already in the patient.
摘要翻译： 一种用于血管使用的医疗夹持装置（10），具有外护套（12），在外护套（12）内延伸到远侧末端部分（54））的细长控制构件（50）和近端控制组件 ）包括连接到细长控制构件（50）的致动部分（24）。 远侧末端部分（54）相邻的是抓握部分（70,70'），其可从外护套（12）延伸以产生用于抓握目标物体（T）的环（74,74'），用于重新定位 血管系统或用于从患者移除的环，其中环可缩回到外护套中，以在装置移动期间将目标物体抵靠装置（10）保持。 细长控制构件（50）优选地是具有完全延伸穿过其中的内腔（58）的插管或管，用于放置在已经在患者体内的导丝（28）上。
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公开(公告)号：US07713275B2
公开(公告)日：2010-05-11
申请号：US10814989
申请日：2004-03-31
IPC分类号： A61B17/08
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/22035 , A61B2017/22038 , A61B2017/2215 , A61B2090/08021 , A61F2/95
摘要： The present invention provides a medical grasping device including an an elongate control member, an outer sheath, and an actuation section. The elongate control member includes an atraumatic distal tip section, a proximal end portion, and a grasping portion positioned between the proximal end portion and the distal tip section. The outer sheath includes a distal end and a proximal end, and has a passageway that extends between the distal and proximal ends. The elongate control member is slidable within the passageway and its proximal end portion is connected to the actuation section. The actuation section is operated to move the grasping portion in and out of the distal end of the outer sheath and includes a retraction mechanism that biases the actuation section and hence the grasping portion toward a retracted state.
摘要翻译： 本发明提供一种包括细长控制构件，外护套和致动部的医疗把持装置。 细长控制构件包括无创伤的远侧末端部分，近端部分和位于近端部分和远侧末梢部分之间的把持部分。 外护套包括远端和近端，并且具有在远端和近端之间延伸的通道。 细长控制构件可在通道内滑动，并且其近端部分连接到致动部分。 致动部分被操作以将抓握部分移入和移出外护套的远端，并且包括将致动部分并且因此把持部分朝向缩回状态偏压的缩回机构。
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公开(公告)号：US07776052B2
公开(公告)日：2010-08-17
申请号：US10003011
申请日：2001-11-01
IPC分类号： A61F11/00
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/22035 , A61B2017/22038 , A61B2017/2215 , A61B2090/08021 , A61F2/95
摘要： A medical grasping device (10) for vascular use, having an outer sheath (12), an elongate control member (50) extending within an outer sheath (12) to a distal tip section (54), and a proximal control assembly (22) including an actuation section (24) joined to the elongate control member (50). Adjacent to the distal tip section (54) is a grasping portion (70,70′) that is extendable from the outer sheath (12) to create loops (74,74′) for grasping a target object (T) for repositioning within the vascular system, or for removal from the patient, with loops being retractable into the outer sheath to hold the target object against the device (10) during movement of the device. Elongate control member (50) is preferably a cannula or tube having a lumen (58) extending completely therethrough for placement over a guide wire (28) already in the patient.
摘要翻译： 一种用于血管使用的医疗夹持装置（10），具有外护套（12），在外护套（12）内延伸到远侧末端部分（54））的细长控制构件（50）和近端控制组件 ）包括连接到细长控制构件（50）的致动部分（24）。 与远侧末端部分（54）相邻的是抓握部分（70,70'），其可从外部护套（12）延伸以产生用于抓握目标物体（T）的环（74,74'），用于重新定位 血管系统或用于从患者移除的环，其中环可缩回到外护套中，以在装置移动期间将目标物体抵靠装置（10）保持。 细长控制构件（50）优选地是具有完全延伸穿过其中的内腔（58）的插管或管，用于放置在已经在患者体内的引导线（28）上。
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公开(公告)号：US09277904B2
公开(公告)日：2016-03-08
申请号：US13111338
申请日：2011-05-19
申请人： Ram H. Paul, Jr. , Cleon Stanley , Brian L. Bates , F. Joseph Obermiller , Thomas A. Osborne , Sean Chambers
发明人： Ram H. Paul, Jr. , Cleon Stanley , Brian L. Bates , F. Joseph Obermiller , Thomas A. Osborne , Sean Chambers
CPC分类号： A61B17/0057 , A61B17/3468 , A61B2017/00004 , A61B2017/00592 , A61B2017/00597 , A61B2017/00623 , A61B2017/00628 , A61B2017/00641 , A61B2017/00659 , A61B2017/00663 , A61B2017/0496 , A61B2017/06176
摘要： Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.
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5.发明授权Tubular devices having reversible components for deployment of endoluminal occluders and related methods and systems 有权具有用于部署腔内封堵器的可逆组件的管状装置及相关方法和系统公开(公告)号：US08540760B2
公开(公告)日：2013-09-24
申请号：US12164520
申请日：2008-06-30
申请人： Ram H. Paul, Jr. , Jacob A. Flagle , Brian C. Case
发明人： Ram H. Paul, Jr. , Jacob A. Flagle , Brian C. Case
IPC分类号： A61F2/84
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12136 , A61B17/12181 , A61B17/1219 , A61B17/3468 , A61B2017/1205
摘要： Described are devices, methods, and systems useful for deploying one or more occlusive prostheses within the vasculature of a patient. Illustrative devices can include a deployment tube or sheath that contains an occlusive prosthesis, wherein a segment of the sheath is reversible by a user so as to deploy the prosthesis from the sheath lumen within a bodily lumen of a patient.
摘要翻译： 描述了用于在患者的脉管系统内部署一个或多个闭塞假体的装置，方法和系统。 示例性装置可以包括包含闭塞假体的展开管或护套，其中护套的一部分可由使用者逆转，以便将该假体从皮肤内腔部署到患者体内。
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公开(公告)号：US08506583B2
公开(公告)日：2013-08-13
申请号：US13593088
申请日：2012-08-23
申请人： Ram H. Paul, Jr.
发明人： Ram H. Paul, Jr.
IPC分类号： A61B17/22
CPC分类号： A61F2/95 , A61F2/06 , A61F2/064 , A61F2002/8483 , A61F2002/9517
摘要： A method for open surgical repair of a damaged portion of an artery or vein. A tubular medical assembly may include one or more shaped members, such as microbarbs, configured to anchor into the tunica intima and the tunica media of the vessel wall, and not to the tunic adventitia and vasa vasorum. The medical assembly is delivered to the damaged vessel portion via a delivery device through an open air pathway, and forms a conduit between transected ends of the damaged vessel.
摘要翻译： 一种用于开放性手术修复动脉或静脉损伤部分的方法。 管状医疗组件可以包括一个或多个成形构件，例如微巴，构造成锚定到血管壁的内膜和中膜，而不是外套和血管充血。 医疗组件经由输送装置通过开放空气通道输送到损坏的容器部分，并且在损坏的容器的横截面之间形成导管。
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公开(公告)号：US08403979B2
公开(公告)日：2013-03-26
申请号：US12121453
申请日：2008-05-15
申请人： Ram H. Paul, Jr.
发明人： Ram H. Paul, Jr.
IPC分类号： A61F2/06
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054
摘要： The disclosure relates to an expandable valve prosthesis for regulating flow through a body vessel. The prosthesis comprises a frame configured to form a laterally asymmetric partial sinus and a valve member.
摘要翻译： 本公开涉及一种用于调节通过身体血管的流动的可扩张瓣膜假体。 假体包括构造成形成横向不对称的部分窦和瓣膜构件的框架。
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公开(公告)号：US08313526B2
公开(公告)日：2012-11-20
申请号：US12273168
申请日：2008-11-18
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2/24 , A61F2/2418 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0058
摘要： The disclosure relates to support frames for prosthetic implantable valves. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.
摘要翻译： 本公开涉及用于假体植入式阀的支撑框架。 支撑框架可以包括多个对称排列的互连的U形构件结构。 优选的支撑框架是包围纵向轴线并且包括面向支撑框架的远端或近端的多个U形构件结构的管状结构。 每个U形构件结构可以连接到面向相反纵向方向的单个纵向相邻的U形构件以及两个横向相邻的U形构件。
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公开(公告)号：US07678144B2
公开(公告)日：2010-03-16
申请号：US12019987
申请日：2008-01-25
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2421 , A61F2/2475
摘要： The invention relates to a prosthetic valve for regulating fluid flow through a body lumen. The valve includes a frame and a valve member comprising at least one semi-rigid leaflet and at least one flexible leaflet. The at least one semi-rigid leaflet comprises a first portion and a second portion, the first portion attached to the frame and the second portion free of the frame. The at least one semi-rigid leaflet is slanted in a retrograde direction from the second portion to the first portion. The at least one flexible leaflet comprises a first portion and a second portion, the first portion attached to the frame and the second portion free of the frame. The at least one flexible leaflet is slanted in a retrograde direction from the first portion to the second portion when at rest.
摘要翻译： 本发明涉及一种用于调节通过体腔的流体流动的人造瓣膜。 阀包括框架和阀构件，阀构件包括至少一个半刚性小叶和至少一个柔性小叶。 至少一个半刚性小叶包括第一部分和第二部分，第一部分附接到框架，第二部分没有框架。 至少一个半刚性小叶从第二部分向第一部分沿逆行方向倾斜。 所述至少一个柔性小叶包括第一部分和第二部分，所述第一部分附接到所述框架并且所述第二部分没有所述框架。 当静止时，至少一个柔性小叶在从第一部分到第二部分的逆行方向上倾斜。
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公开(公告)号：US10226264B2
公开(公告)日：2019-03-12
申请号：US13555685
申请日：2012-07-23
申请人： Charles L. McIntosh , Ram H. Paul, Jr. , Darin G. Schaeffer , M. Kem Hawkins , Frank J. Fischer, Jr. , Grant T. Hoffman
发明人： Charles L. McIntosh , Ram H. Paul, Jr. , Darin G. Schaeffer , M. Kem Hawkins , Frank J. Fischer, Jr. , Grant T. Hoffman
摘要： A device for thrombolytic therapy is provided. The device includes an elongate catheter with a distal end portion and a proximal end portion and a first lumen extending through both distal and proximal end portions. The distal end portion of the catheter includes an echogenic tubular potion that defines or surrounds a portion of the first lumen. An expandable balloon coaxially surrounds the tubular portion. The tubular portion additionally includes a plurality of indentations defined upon an outer surface thereof.
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