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公开(公告)号：US20120095233A1
公开(公告)日：2012-04-19
申请号：US12103882
申请日：2008-04-16
申请人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera , Nicholas Scorah
发明人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera , Nicholas Scorah
IPC分类号： C07D471/04 , C07D209/88
CPC分类号： C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译： 提供化合物用于与包含选自以下的化合物的激酶一起使用：其中变量如本文所定义。 还提供了包含这些化合物的药物组合物，试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号：US08278450B2
公开(公告)日：2012-10-02
申请号：US12103882
申请日：2008-04-16
申请人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
发明人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
IPC分类号： C07D471/00 , C07D209/88
CPC分类号： C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译： 提供化合物用于与包含选自以下的化合物的激酶一起使用：其中变量如本文所定义。 还提供了包含这些化合物的药物组合物，试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号：US20100120717A1
公开(公告)日：2010-05-13
申请号：US12444957
申请日：2007-10-08
申请人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
发明人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
IPC分类号： A61K31/675 , C07D471/02 , A61K31/437 , C07D471/12 , C07D413/14 , A61K31/5377 , C07D401/14 , A61K31/496 , A61K31/397 , C07F9/06 , A61P35/00 , A61P29/00 , A61P25/00
CPC分类号： C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Compounds are provided for use with kinases that comprise a compound selected from the group consisting of formula (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture in comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译： 化合物被提供用于包含选自式（I）的化合物的激酶，其中变量如本文所定义。 还提供了包含这些化合物的药物组合物，试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号：US20120252761A1
公开(公告)日：2012-10-04
申请号：US13437234
申请日：2012-04-02
申请人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
发明人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Hasanthi Wijesekera
IPC分类号： A61K31/675 , C07F9/6561
CPC分类号： C07D471/14 , C07D241/18 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
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公开(公告)号：US20090156557A1
公开(公告)日：2009-06-18
申请号：US12103625
申请日：2008-04-15
申请人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
发明人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
IPC分类号： C07D487/04 , A61K31/437 , A61K31/496 , A61K31/5377 , A61K31/675 , C07F9/576 , C12N9/99 , A61P25/28 , A61P29/00 , A61P25/00 , A61P35/00
CPC分类号： C07F9/6561 , C07D471/04
摘要： Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
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公开(公告)号：US20100160633A1
公开(公告)日：2010-06-24
申请号：US12706837
申请日：2010-02-17
申请人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
发明人： Jason W. Brown , Qing Dong , Bheema R. Paraselli , Jeffrey A. Stafford , Xianchang Gong , Yan Liu , Nicholas Scorah , Michael B. Wallace
IPC分类号： C07F9/06
CPC分类号： C07F9/6561 , C07D471/04
摘要： Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译： 提供化合物用于与包含选自以下的化合物的激酶一起使用：其中变量如本文所定义。 还提供了包含这些化合物的药物组合物，试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
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公开(公告)号：US08119655B2
公开(公告)日：2012-02-21
申请号：US11539857
申请日：2006-10-09
IPC分类号： A61K31/437 , C07D471/04
CPC分类号： C07D471/04 , C07D471/12 , C07D487/04 , C07D487/14
摘要： Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
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公开(公告)号：US20100216765A1
公开(公告)日：2010-08-26
申请号：US12755301
申请日：2010-04-06
申请人： Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： A61K31/519 , C07D487/04 , A61K31/5377 , A61K31/53 , C07D471/04 , A61P35/00 , A61P25/00 , A61P37/02 , A61P25/28 , A61P3/10
CPC分类号： C07D487/04
摘要： Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译： 化合物，药物组合物和试剂盒提供用于包含选自以下的化合物的激酶：其中变量如本文所定义。
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公开(公告)号：US20100190816A1
公开(公告)日：2010-07-29
申请号：US12708304
申请日：2010-02-18
IPC分类号： A61K31/4745 , C07D491/02
CPC分类号： C07D471/04 , C07D471/12 , C07D487/04 , C07D487/14
摘要： Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译： 提供化合物，药物组合物，试剂盒和方法用于包含选自以下的化合物的激酶：其中变量如本文所定义。
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公开(公告)号：US08288536B2
公开(公告)日：2012-10-16
申请号：US12755301
申请日：2010-04-06
申请人： Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Qing Dong , David J. Hosfield , Bheema R. Paraselli , Nicholas Scorah , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： C07D487/04 , A61K31/517 , A61P19/02
CPC分类号： C07D487/04
摘要： Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译： 化合物，药物组合物和试剂盒提供用于包含选自以下的化合物的激酶：其中变量如本文所定义。
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