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    Methods And Compositions For Hydrophobic Modification Of Oral Cavity Surfaces
    8.
    发明申请
    Methods And Compositions For Hydrophobic Modification Of Oral Cavity Surfaces 审中-公开
    口腔表面疏水改性的方法和组合物

    公开(公告)号：US20110089073A1

    公开(公告)日：2011-04-21

    申请号：US12879214

    申请日：2010-09-10

    申请人： Arif Ali Baig ,  Jayanth Rajaiah ,  George Endel Deckner ,  William Michael Glandorf

    发明人： Arif Ali Baig ,  Jayanth Rajaiah ,  George Endel Deckner ,  William Michael Glandorf

    IPC分类号： B65D85/00 ,  A61K8/46 ,  A61Q11/00

    CPC分类号： A61Q11/00 ,  A61K8/24 ,  A61K8/55 ,  A61K8/556 ,  A61Q11/02

    摘要： Oral care compositions containing agents that are effective for treating and modifying teeth and mucosal surfaces to be hydrophobic are disclosed. Hydrophobic modification of teeth and other oral cavity surfaces imparts a variety of end use benefits including prevention of caries, erosion, wear, staining, sensitivity and desquamation as well as providing shine, smoothness and positive tooth feel benefits. The compositions contain selected surface active organophosphate compounds that deposit and adhere to teeth and other oral cavity surfaces forming a hydrophobic coating having prolonged retention thereon. By forming a “hydrophobic coating” on the oral cavity surface is meant that the hydrophobic character of the surface is increased as measured, for example, by an increase of at least about 10 degrees in the water contact angle of the surface after treatment. The increased hydrophobic character of the surface is maintained for a period of at least about 5 minutes and desirably longer such as at least about 10, at least about 20 or at least about 30 minutes. The compositions may contain additional hydrophobic materials to further increase hydrophobicity of the surface and/or functionality of the coating to provide surface protection and many other benefits.

    摘要翻译： 公开了含有有效治疗和改变牙齿和粘膜表面是疏水性的试剂的口腔护理组合物。 牙齿和其他口腔表面的疏水改性赋予各种最终用途益处，包括预防龋齿，侵蚀，磨损，染色，敏感性和脱屑，以及提供光泽，光滑度和积极的牙齿感受益处。 组合物含有选择的表面活性有机磷酸盐化合物，其沉积并粘附到牙齿和其它口腔表面上，形成具有延长的保留性的疏水涂层。 通过在口腔表面上形成“疏水性涂层”是指表面的疏水特性例如通过在处理后表面的水接触角增加至少约10度来测量而增加。 表面增加的疏水特性保持至少约5分钟，期望更长，例如至少约10，至少约20或至少约30分钟。 组合物可以含有另外的疏水材料以进一步增加涂层的表面和/或功能性的疏水性，以提供表面保护和许多其它益处。

    Method of reducing staining of stannous in dentifrice compositions
    10.
    发明授权
    Method of reducing staining of stannous in dentifrice compositions 有权
    减少洁牙剂组合物中亚锡染色的方法

    公开(公告)号：US06350436B1

    公开(公告)日：2002-02-26

    申请号：US09451420

    申请日：1999-11-30

    申请人： William Michael Glandorf ,  Lori Ann Bacca

    发明人： William Michael Glandorf ,  Lori Ann Bacca

    IPC分类号： A61K716

    CPC分类号： A61Q11/00 ,  A61K8/21 ,  A61K8/24 ,  A61K2800/52 ,  A61K2800/88

    摘要： Disclosed are methods for reducing the staining of dentifrice composition containing stannous comprising administering to a subject the dentifrice composition. The dentifrice composition is a dual phase dentifrice and is contained in physically separated compartments of a dentifrice dispenser. The first dentifrice composition comprises an effective amount of one or more linear polyphosphates having an average chain length of about 4 or more and has a total water content of up to about 20%. The second dentifrice composition comprises an effective amount of stannous ions. The molar ratio of polyphosphate anion to stannous ion is from about 0.2:1 to about 5:1 and the efficacy of the stannous ion in the dentifrice is not reduced by the polyphosphate. The dentifrice composition may alternatively be a single phase dentifrice. The single phase dentifrice will comprise an effective amount of one or more linear polyphosphates having an average chain length of about 4 or more and an effective amount of a stannous anion. The single phase dentifrice has a total water content of up to about 20%, the stannous ion is not delivered from stannous fluoride, a molar ratio of polyphosphate anion to stannous ion is from about 0.2:1 to about 5:1, and the efficacy of the stannous ion in the dentifrice is not reduced by the polyphosphate.

    摘要翻译： 公开了减少含有亚锡的牙粉组合物染色的方法，包括向受试者施用洁齿剂组合物。 洁牙剂组合物是双相洁齿剂，并且包含在洁齿剂分配器的物理分离的隔室中。 第一洁牙剂组合物包含有效量的一种或多种平均链长为约4或更大并且总含水量高达约20％的线性多磷酸盐。 第二洁牙剂组合物包含有效量的亚锡离子。 多磷酸根阴离子与亚锡离子的摩尔比为约0.2:1至约5:1，并且多磷酸盐不会降低洁牙剂中的亚锡离子的功效。 洁齿剂组合物可以替代地是单相洁齿剂。 单相洁齿剂将包含有效量的一种或多种平均链长为约4或更大的线性多磷酸酯和有效量的亚锡阴离子。 单相洁齿剂的总含水量高达约20％，亚锡离子不会从氟化亚锡输送，多磷酸根阴离子与亚锡离子的摩尔比为约0.2:1至约5:1，效力 的洁齿剂中的亚锡离子不被多磷酸盐还原。