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    System and method for prevention of radiocontrast induced nephropathy
    6.
    发明申请
    System and method for prevention of radiocontrast induced nephropathy 审中-公开
    用于预防放射性对照诱导的肾病的系统和方法

    公开(公告)号：US20070213686A1

    公开(公告)日：2007-09-13

    申请号：US11347008

    申请日：2006-02-03

    申请人： Vandana Mathur ,  Craig Ball ,  Jeffrey Elkins ,  Harry Goodson ,  Samir Patel

    发明人： Vandana Mathur ,  Craig Ball ,  Jeffrey Elkins ,  Harry Goodson ,  Samir Patel

    IPC分类号： A61B19/00

    CPC分类号： A61M5/1723 ,  A61B90/00 ,  A61B2017/22082 ,  A61M5/007 ,  A61M25/0068 ,  A61M2005/1403 ,  A61M2025/0037 ,  A61M2025/1045

    摘要： An apparatus and method particularly useful in treatments and therapies directed at the kidneys such as the prevention of radiocontrast nephropathy (RCN) arising from diagnostic procedures using iodinated contrast materials. A series of treatment schemes are provided based upon local therapeutic agent delivery to the kidneys that can be used as a prophylactic treatment for patients undergoing interventional procedures that have been identified as being at an elevated risk for developing RCN as well as for low risk patients. The methods may include pre-exposure and post contrast exposure treatments alone or in combination with the local delivery of therapeutic agents to the kidneys. Among the agents identified for such treatments are normal saline and the vasodilators papaverine and fenoldopam mesylate and appropriate dosing is provided.

    摘要翻译： 特别适用于针对肾脏的治疗和疗法的装置和方法，例如使用碘化造影剂的诊断程序引起的放射性对比肾病（RCN）的预防。 提供了一系列基于局部治疗剂递送到肾脏的治疗方案，其可用作对已经被鉴定为发展RCN和低风险患者的高风险的介入手术的患者的预防性治疗。 所述方法可以包括单独的暴露前曝光和造影后处理，或与治疗剂局部递送到肾脏的方法。 鉴定用于这种治疗的药剂是生理盐水，并且提供了血管扩张剂罂粟碱和甲磺酸芬诺多胺，并提供适当的给药。

    Rapid-exchange delivery systems for self-expanding stents
    7.
    发明申请
    Rapid-exchange delivery systems for self-expanding stents 有权
    用于自扩张支架的快速交换输送系统

    公开(公告)号：US20050113902A1

    公开(公告)日：2005-05-26

    申请号：US10720032

    申请日：2003-11-20

    申请人： Timothy Geiser ,  Charles Peterson ,  Andy Denison ,  Stephanie Klocke ,  Samir Patel ,  Joanna Lubas ,  Joanne Lumauig ,  Kathy Lind ,  Keif Fitzgerald

    发明人： Timothy Geiser ,  Charles Peterson ,  Andy Denison ,  Stephanie Klocke ,  Samir Patel ,  Joanna Lubas ,  Joanne Lumauig ,  Kathy Lind ,  Keif Fitzgerald

    IPC分类号： A61F2/84 ,  A61L29/00 ,  A61M25/00 ,  A61F2/06

    CPC分类号： A61F2/95 ,  A61F2/966 ,  A61M2025/0183

    摘要： A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.

    摘要翻译： 提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。 外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。 内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。 内部构件也可以由具有支撑心轴的近端部分制成。 可以使用线圈管来形成附接到内部构件的导丝接收构件。

    NOVEL POLYMORPHIC FORM OF TERIFLUNOMIDE SALTS
    10.
    发明申请
    NOVEL POLYMORPHIC FORM OF TERIFLUNOMIDE SALTS 审中-公开
    新型多元醇盐的多晶型

    公开(公告)号：US20120171490A1

    公开(公告)日：2012-07-05

    申请号：US13382848

    申请日：2010-06-22

    申请人： Ravi Ponnaiah ,  Samir Patel ,  Snehal Dhol ,  Vishal Ray

    发明人： Ravi Ponnaiah ,  Samir Patel ,  Snehal Dhol ,  Vishal Ray

    IPC分类号： B32B5/16 ,  C07C255/44

    CPC分类号： C07C255/23 ,  Y10T428/2982

    摘要： The present invention provides a new polymorph Form I of Teriflunomide sodium and a process for preparation thereof. The present invention provides an amorphous form of Teriflunomide sodium and a process for preparation thereof. The present invention provides a new polymorph Form I of Teriflunomide potassium and a process for preparation thereof. The present invention provides an amorphous form of Teriflunomide potassium and a process for preparation thereof. The present invention also provides particle size of Teriflunomide and its salts.

    摘要翻译： 本发明提供了特比氟米特钠的新型多晶型物I及其制备方法。 本发明提供了非晶形式的特立氟铵，及其制备方法。 本发明提供了特比氟铵的新型多晶型物I及其制备方法。 本发明提供了非晶形式的特菲仑铵，及其制备方法。 本发明还提供特菲仑铵及其盐的粒度。