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    Catheters with fluorescent temperature sensors
    4.
    发明授权
    Catheters with fluorescent temperature sensors 有权
    带荧光温度传感器的导管

    公开(公告)号：US08007444B2

    公开(公告)日：2011-08-30

    申请号：US11077322

    申请日：2005-03-10

    申请人： Jaydeep Y. Kokate ,  Eric M. DoBrava ,  Scott R. Smith

    发明人： Jaydeep Y. Kokate ,  Eric M. DoBrava ,  Scott R. Smith

    IPC分类号： A61B5/00 ,  A61B5/02 ,  A61B18/18

    CPC分类号： A61B5/01 ,  A61B5/6853 ,  A61B5/6859 ,  A61B5/6885

    摘要： A catheter with a fluorescent temperature sensor is shown and described. The catheter includes a lumen, a fiber-optic cable that extends through the lumen. A distal end of the fiber-optic cable is coated with a fluorescent material and a proximal end of the fiber-optic cable is connected to a console. The console includes a light source for transmitting light through the fiber-optic cable for exciting the fluorescent material. The console further includes a photo multiplier tube for converting light emitted by the excited fluorescent material to a plurality of analogue voltage signals. The console further includes a digital oscilloscope linked to the photo multiplier tube for converting the plurality of analogue voltage signals to at least one digital signal. The console further includes a processor linked to the digital oscilloscope for converting the at least one digital signal to a temperature value for the distal end of the fiber-optic cable.

    摘要翻译： 显示和描述具有荧光温度传感器的导管。 导管包括内腔，延伸穿过内腔的光纤电缆。 光纤电缆的远端涂覆有荧光材料，光纤电缆的近端连接到控制台。 控制台包括用于通过光纤电缆传输光以激发荧光材料的光源。 控制台还包括一个用于将由激发的荧光材料发射的光转换成多个模拟电压信号的光电倍增管。 控制台还包括连接到光电倍增管的数字示波器，用于将多个模拟电压信号转换成至少一个数字信号。 控制台还包括连接到数字示波器的处理器，用于将至少一个数字信号转换为光纤电缆的远端的温度值。

    Aspirating balloon catheter for treating vulnerable plaque
    6.
    发明授权
    Aspirating balloon catheter for treating vulnerable plaque 有权
    用于治疗易损斑块的吸气球导管

    公开(公告)号：US07189250B2

    公开(公告)日：2007-03-13

    申请号：US10044277

    申请日：2002-01-10

    申请人： Eric M. DoBrava ,  Jaydeep Y. Kokate

    发明人： Eric M. DoBrava ,  Jaydeep Y. Kokate

    IPC分类号： A61M29/00

    CPC分类号： A61M25/104 ,  A61B17/22 ,  A61B17/320708 ,  A61B2017/22079 ,  A61B2017/22081 ,  A61B2217/005 ,  A61M2025/1013 ,  A61M2025/1072 ,  A61M2025/1075 ,  A61M2025/109

    摘要： Devices and methods for extracting core material contained in plaque deposits inside a blood vessel are presented. A device in accordance with one embodiment of the invention includes a catheter having an elongate shaft, a collection array of a plurality of collection lumens disposed about the distal portion of the elongate shaft, a means for radially extending and/or collapsing the collection array, and a suction means for extracting material from the lumen of the blood vessel. A method in accordance with one embodiment of the present invention includes the steps of inserting the distal portion of the catheter into a lumen of the blood vessel, positioning the distal end of the collection array proximate plaque deposits, extending the collection array to rupture the plaque deposits and urging core material therefrom, and extracting the material using a suction means fluidly coupled to the proximal end of the collection array.

    摘要翻译： 提出了用于提取包含在血管内的斑块沉积物中的核心材​​料的装置和方法。 根据本发明的一个实施例的装置包括具有细长轴的导管，围绕细长轴的远端部分设置的多个收集腔的收集阵列，用于径向延伸和/或收缩收集阵列的装置， 以及用于从血管的内腔提取物质的抽吸装置。 根据本发明的一个实施例的方法包括以下步骤：将导管的远端部分插入血管的内腔，将收集阵列的远端靠近斑块沉积物，延伸收集阵列以破裂斑块 沉积和推动芯材，并且使用流体耦合到收集阵列的近端的抽吸装置提取材料。

    pH measuring balloon
    7.
    发明授权
    pH measuring balloon 有权
    pH测量气球

    公开(公告)号：US06999807B2

    公开(公告)日：2006-02-14

    申请号：US10349674

    申请日：2003-01-23

    申请人： Scott R. Smith ,  Jaydeep Y. Kokate ,  Leonard B. Richardson ,  Eric M. Dobrava

    发明人： Scott R. Smith ,  Jaydeep Y. Kokate ,  Leonard B. Richardson ,  Eric M. Dobrava

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14539 ,  A61B5/1459

    摘要： The present invention relates to devices and methods for measuring the pH of blood in the vicinity of a vulnerable plaque. A balloon including an opto-electric device may be positioned proximate a vulnerable plaque. The balloon can be inflated to partially occlude blood flow enabling interaction between lipid laden blood and pH-sensitive material either within the balloon or on the wall(s) of the balloon. The selected pH-sensitive material is one whose optical properties change as a function of the pH of blood in the vasculature. An opto-electric device may be used for measuring the optical property and/or the change in the optical characteristics of the pH-sensitive compound.

    摘要翻译： 本发明涉及用于测量易损斑块附近血液pH值的装置和方法。 包括光电装置的气囊可以位于易损斑块附近。 气囊可以被充气以部分阻塞血液流动，从而能够在球囊内或气球的壁上与脂质负载血液和pH敏感材料之间的相互作用。 选择的pH敏感材料是其光学性质随脉管系统中血液pH值变化的物质。 可以使用光电装置来测量pH敏感化合物的光学特性和/或光学特性的变化。

    Catheters with fluorescent temperature sensors
    8.
    发明授权
    Catheters with fluorescent temperature sensors 有权
    带荧光温度传感器的导管

    公开(公告)号：US06890307B2

    公开(公告)日：2005-05-10

    申请号：US10043051

    申请日：2002-01-09

    申请人： Jaydeep Y. Kokate ,  Eric M. Dobrava ,  Scott R. Smith

    发明人： Jaydeep Y. Kokate ,  Eric M. Dobrava ,  Scott R. Smith

    IPC分类号： A61B5/00 ,  A61B5/01

    CPC分类号： A61B5/01 ,  A61B5/6853 ,  A61B5/6859 ,  A61B5/6885

    摘要： A catheter with a fluorescent temperature sensor is shown and described. The catheter includes a lumen, a fiber-optic cable that extends through the lumen. A distal end of the fiber-optic cable is coated with a fluorescent material and a proximal end of the fiber-optic cable is connected to a console. The console includes a light source for transmitting light through the fiber-optic cable for exciting the fluorescent material. The console further includes a photo multiplier tube for converting light emitted by the excited fluorescent material to a plurality of analog voltage signals. The console further includes a digital oscilloscope linked to the photo multiplier tube for converting the plurality of analog voltage signals to at least one digital signal. The console further includes a processor linked to the digital oscilloscope for converting the at least one digital signal to a temperature value for the distal end of the fiber-optic cable.

    摘要翻译： 显示和描述具有荧光温度传感器的导管。 导管包括内腔，延伸穿过内腔的光纤电缆。 光纤电缆的远端涂覆有荧光材料，光纤电缆的近端连接到控制台。 控制台包括用于通过光纤电缆传输光以激发荧光材料的光源。 控制台还包括用于将由激发的荧光材料发射的光转换成多个模拟电压信号的光电倍增管。 控制台还包括连接到光电倍增管的数字示波器，用于将多个模拟电压信号转换成至少一个数字信号。 控制台还包括连接到数字示波器的处理器，用于将至少一个数字信号转换为光纤电缆的远端的温度值。

    Aspirating devices for removal of thrombus/lipid from a body lumen
    9.
    发明授权
    Aspirating devices for removal of thrombus/lipid from a body lumen 有权
    用于从体腔去除血栓/脂质的抽吸装置

    公开(公告)号：US06790196B2

    公开(公告)日：2004-09-14

    申请号：US10025670

    申请日：2001-12-18

    申请人： Jaydeep Y. Kokate ,  Eric M. DoBrava

    发明人： Jaydeep Y. Kokate ,  Eric M. DoBrava

    IPC分类号： A61M100

    CPC分类号： A61M25/1011 ,  A61B17/22 ,  A61B2017/22054 ,  A61B2017/22082 ,  A61B2217/005 ,  A61M2025/1052

    摘要： Methods and devices for treating vulnerable plaque deposits within a blood vessel, having an inner surface and one or more plaque deposits containing a core material are disclosed. A device in accordance with an exemplary embodiment of the present invention includes an elongate shaft having a proximal end and a distal end, a balloon disposed about the elongate shaft for engaging one or more plaque deposits and extracting the core material therefrom, a first venturi section disposed proximally of the balloon, and a second venturi section disposed distally of the balloon. An exemplary method in accordance with the present invention may include the steps of inserting a distal portion of the catheter into a lumen of the blood vessel, positioning the balloon proximate a plaque deposit, inflating the balloon, creating a first stream of fluid proximally of the balloon, collecting the first stream of fluid proximally of the balloon, creating a second stream of fluid distally of the balloon, and collecting the second stream of fluid distally of the balloon.

    摘要翻译： 公开了一种用于治疗血管内的易损斑块沉积物的方法和装置，其具有内表面和一个或多个含有核心材料的斑块沉积物。 根据本发明的示例性实施例的装置包括具有近端和远端的细长轴，围绕细长轴设置的气囊，用于接合一个或多个斑块沉积物并从其中提取芯材料;第一文丘里管部分 设置在气囊的近侧，以及设置在气囊的远侧的第二文丘里管部分。 根据本发明的示例性方法可以包括以下步骤：将导管的远端部分插入血管的内腔，将球囊定位在斑块沉积物附近，使气囊膨胀，从而产生第一流体流 气球，收集气囊近端的第一流体流，产生气囊的远端的第二流体流，并收集气囊的远端的第二流体流。