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    MEDICAL DEVICES HAVING A COATING FOR ELECTROMAGNETICALLY-CONTROLLED RELEASE OF THERAPEUTIC AGENTS
    1.
    发明申请
    MEDICAL DEVICES HAVING A COATING FOR ELECTROMAGNETICALLY-CONTROLLED RELEASE OF THERAPEUTIC AGENTS 审中-公开
    具有用于电磁控制释放治疗剂的涂层的医疗装置

    公开(公告)号：US20100047313A1

    公开(公告)日：2010-02-25

    申请号：US12544577

    申请日：2009-08-20

    Applicant: Tom PRIEBE ,  Umang ANAND ,  Lance GIBSON ,  Les CLAPP ,  Michael KUEHLING

    Inventor： Tom PRIEBE ,  Umang ANAND ,  Lance GIBSON ,  Les CLAPP ,  Michael KUEHLING

    IPC: A61F2/04 ,  A61K31/337 ,  A61P7/00

    CPC classification number: A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/606 ,  C08L101/12

    Abstract: Medical devices having a coating comprising an ionic polymer for electromagnetically-controlled release of a therapeutic agent. Release of the therapeutic agent from the coating is facilitated or modulated by the application of an electromagnetic field to the medical device. Exposure to the electromagnetic field may cause the release of the therapeutic agent in various ways, including electrochemical changes in the ionic polymer, structural changes in the coating and/or ionic polymers, changes in the permeability of the coating, changes in the orientation of the ionic polymers, or motion of the ionic polymers. Also disclosed are methods for delivering a therapeutic agent using electromagnetic fields.

    Abstract translation: 具有包含用于电磁控制释放治疗剂的离子聚合物的涂层的医疗装置。 通过向医疗装置施加电磁场来促进或调节治疗剂从涂层的释放。 暴露于电磁场可能导致治疗剂以各种方式释放，包括离子聚合物的电化学变化，涂层和/或离子聚合物的结构变化，涂层渗透性的变化， 离子聚合物或离子聚合物的运动。 还公开了使用电磁场递送治疗剂的方法。

    Porous, lubricated mixing tube for abrasive, fluid jet
    7.
    发明授权
    Porous, lubricated mixing tube for abrasive, fluid jet 失效
    多孔润滑混合管用于磨料，流体喷射

    公开(公告)号：US06837775B2

    公开(公告)日：2005-01-04

    申请号：US10010663

    申请日：2001-12-06

    Applicant: Umang Anand ,  Joseph Katz

    Inventor： Umang Anand ,  Joseph Katz

    IPC: B24C1/04 ,  B24C5/04 ,  B24B1/00

    CPC classification number: B24C5/04 ,  B24C1/045

    Abstract: An abrasive, fluid jet cutting apparatus, and its method of construction and operation, are disclosed that reduce the wear and erosion problems typically experienced in the cutting jet's mixing tube. This improved fluid jet cutting apparatus comprises (a) a chamber having an inlet for receiving a pressurized fluid jet, a port for receiving a flow of abrasive particles which are entrained into the fluid jet, and an exit through which the fluid jet and entrained abrasives exit the chamber, (b) a mixing tube having an entry port for receiving said fluid jet and entrained abrasives, an inner wall for directing the flow of said fluid jet and entrained abrasives, and an outlet port through which said fluid jet and entrained abrasives exit said tube, wherein the tube entry port is proximate the chamber exit, (c) a lubricating fluid reservoir that surrounds at least a portion of the outer wall of the mixing tube, (d) wherein at least a portion of the mixing tube wall is porous, and (e) wherein the lubricating fluid passes from the lubricating reservoir and through the porous wall to lubricate at least a portion of the surface of the mixing tube wall so as to resist erosion of the tube wall when the fluid jet and entrained abrasives flow through the mixing tube.

    Porous, lubricated nozzle for abrasive fluid suspension jet
    9.
    发明授权
    Porous, lubricated nozzle for abrasive fluid suspension jet 失效
    用于研磨液悬浮喷嘴的多孔润滑喷嘴

    公开(公告)号：US06688947B2

    公开(公告)日：2004-02-10

    申请号：US10067591

    申请日：2002-02-05

    Applicant: Umang Anand ,  Joseph Katz

    Inventor： Umang Anand ,  Joseph Katz

    IPC: B24B100

    CPC classification number: B24C1/045 ,  Y10T83/0591 ,  Y10T137/0469

    Abstract: A nozzle apparatus for use with an abrasive fluid jet cutting system, and its method of construction and operation, are disclosed that reduce the wear and erosion problems typically experienced in the cutting jet's nozzle. This improved nozzle apparatus comprises (a) a nozzle having an entry port for receiving a slurry consisting of a carrier fluid and abrasive particles, an inner wall for directing the flow of the slurry, and an outlet port through which the slurry exits the nozzle, (b) wherein at least a portion of the nozzle wall is porous, and (c) a lubricating fluid chamber that surrounds the porous portion of the outer wall of the nozzle, the chamber having a port where a lubricating fluid enters the chamber, with the chamber port connecting to an input pipe which connects to a filter for filtering contaminants that might clog the pores of the porous portion of the nozzle. The nozzle operates by having the lubricating fluid pass from the lubricating reservoir and through the porous wall to lubricate at least a portion of the surface of the nozzle inner wall so as to resist erosion of the wall, as well as result in an abrasive slurry jet with improved coherence and cutting efficiency.

    Abstract translation: 公开了一种用于磨料流体射流切割系统的喷嘴装置及其结构和操作方法，其减少了切割喷嘴喷嘴中通常经历的磨损和侵蚀问题。 这种改进的喷嘴装置包括（a）喷嘴，其具有用于接收由载体流体和磨料颗粒组成的浆料的入口，用于引导浆料流动的内壁和浆料离开喷嘴的出口， （b）其中所述喷嘴壁的至少一部分是多孔的，以及（c）围绕所述喷嘴的外壁的多孔部分的润滑流体室，所述室具有润滑流体进入所述室的端口， 连接到输入管的室口连接到过滤器，用于过滤可能堵塞喷嘴的多孔部分的孔的污染物。 喷嘴通过使润滑流体从润滑储存器通过并穿过多孔壁以润滑喷嘴内壁的表面的至少一部分以便抵抗壁的侵蚀，并且导致磨料浆料喷射 具有改进的一致性和切割效率。

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