公开(公告)号：US4613708A

公开(公告)日：1986-09-23

申请号：US467648

申请日：1983-02-18

申请人： Jean Riess ,  Francois Jeanneaux ,  Maurice Le Blanc ,  Andre Lantz

发明人： Jean Riess ,  Francois Jeanneaux ,  Maurice Le Blanc ,  Andre Lantz

IPC分类号： A61K31/02 ,  A61K9/107 ,  A61P7/08 ,  C07C17/00 ,  C07C17/25 ,  C07C17/278 ,  C07C21/18 ,  C07C67/00

CPC分类号： C07C21/18 ,  C07C17/25 ,  C07C17/278 ,  Y10S514/832 ,  Y10S514/833

摘要： This invention concerns new branched perfluoroalkylated ethenes, their preparation and their use, in the form of aqueous emulsions, as oxygen carriers, and in particular as blood substitutes or as perfusion agents for the preservation of organs before transplant.

摘要翻译： 本发明涉及新的支化全氟烷基化乙烯，它们的制备方法及其用途，以水性乳液的形式，作为氧载体，特别是作为血液代用品或用于在移植前保存器官的灌注剂。

公开(公告)号：US3983179A

公开(公告)日：1976-09-28

申请号：US544817

申请日：1975-01-28

申请人： Jean Riess ,  Georges Santini ,  Maurice Le Blanc

发明人： Jean Riess ,  Georges Santini ,  Maurice Le Blanc

IPC分类号： C07C17/00 ,  C07C17/26 ,  C07C17/281 ,  C07C21/18 ,  C07C21/19 ,  C07C67/00 ,  C07C21/20

CPC分类号： C07C21/19 ,  C07C17/269 ,  C07C17/281 ,  Y10S514/832

摘要： A polyfluorinated butadiene having the formula ##EQU1## wherein n and m are integers from 1 to 10 and n=m or n.noteq.m, is prepared by reductive coupling, exemplarily with copper, of the corresponding 1,2-bis(perfluoroalkyl)iodoethylene having the formula CF.sub.3 (CF.sub.2).sub.n CH = CI--(CF.sub.2).sub.m CF.sub.3. This iodoethylene is conveniently prepared by a simple addition reaction between a perfluoroalkyl iodide and a perfluoroalkyl acetylene. The perfluoralkylated butadienes are useful as transporters of dissolved gas, particularly of oxygen as in blood substitutes.

摘要翻译： 具有式CF 3（CF 2）n CHCH（CF 2）n CF 3 ANGLE CC ANGLE CF 3（CF 2）m（CF 2）m CF 3的多氟丁二烯，其中n和m是1至10的整数，n = m或n。备注m通过还原 具有式CF 3（CF 2）n CH = Cl - （CF 2）m CF 3的相应的1,2-双（全氟烷基）碘乙烯与铜例子的偶联。 该碘乙烯通过全氟烷基碘和全氟烷基乙炔之间的简单加成反应方便地制备。 全氟烷基化的丁二烯可用作溶解气体，特别是氧气的转运体，如在血液代用品中。

公开(公告)号：US4985550A

公开(公告)日：1991-01-15

申请号：US78626

申请日：1987-07-28

申请人： Brigitte Charpiot ,  Jacques Greiner ,  Maurice Le Blanc ,  Alexandre Manfredi ,  Jean Riess ,  Leila Zarif

发明人： Brigitte Charpiot ,  Jacques Greiner ,  Maurice Le Blanc ,  Alexandre Manfredi ,  Jean Riess ,  Leila Zarif

IPC分类号： B01F17/38 ,  A61K9/00 ,  A61K31/16 ,  A61K31/215 ,  A61K31/34 ,  A61K31/341 ,  A61K31/35 ,  A61K31/357 ,  A61K31/70 ,  A61K31/7024 ,  A61K31/7028 ,  A61K49/00 ,  A61P7/08 ,  B01F17/00 ,  B01F17/42 ,  B01F17/56 ,  C07C43/178 ,  C07C69/63 ,  C07C233/18 ,  C07D307/20 ,  C07D317/22 ,  C07D493/04 ,  C07H13/04 ,  C07H13/06 ,  C07H15/04 ,  C07H15/10 ,  C11D1/00

CPC分类号： A61K9/0026 ,  B01F17/0035 ,  B01F17/0042 ,  B01F17/0057 ,  C07C43/178 ,  C07C43/1787 ,  C07D307/20 ,  C07D493/04 ,  C07H13/04 ,  C07H15/04 ,  C07H15/10 ,  C11D1/004 ,  Y10S514/832 ,  Y10S514/908

摘要： Compounds having a polyhydroxylated hydrophilic moiety, a highly fluorinated moiety and a functional junction group linking said moieties together, wherein said hydrophilic moiety is derived from a polyol or an aminopolyol, and wherein said highly fluorinated moiety consists of a fluorocarbon group wherein at lest 50% of the atoms bonded to the carbon skeleton are fluorine atoms, the other atoms bonded to the carbon skeleton being hydrogen, chlorine or bromine atoms, said highly fluorinated moiety containing at least 4 fluorine atoms; as well as the internal ethers and ketals thereof; process for their preparation; and a compositions containing said compounds as surfactants, together with non polar compounds, for use as gas carriers.