专利检索 ap:("Jean-Christophe CARRY" OR "Gilles DOERFLINGER" OR "Antony BIGOT" OR "Dominique BARBALAT-DAMOUR" OR "Francois CLERC" OR "Arielle GENEVOIS-BORELLA" OR "Baptiste RONAN" OR "Herve MINOUX" OR "Claude BARBERIS" OR "Yves JANIN") AND inv:"Francois CLERC" 第 1 页

1.

发明申请
Substituted Thieno[2,3-c]pyrazoles, Process for Preparing Them, Compositions Containing Them, and Use Thereof 失效
标题翻译：取代噻吩并[2,3-c]吡唑，其制备方法，含有它们的组合物及其用途

公开(公告)号：US20080058402A1

公开(公告)日：2008-03-06

申请号：US11752612

申请日：2007-05-23

申请人： Jean-Christophe CARRY , Gilles DOERFLINGER , Antony BIGOT , Dominique BARBALAT-DAMOUR , Francois CLERC , Arielle GENEVOIS-BORELLA , Baptiste RONAN , Herve MINOUX , Claude BARBERIS , Yves JANIN

发明人： Jean-Christophe CARRY , Gilles DOERFLINGER , Antony BIGOT , Dominique BARBALAT-DAMOUR , Francois CLERC , Arielle GENEVOIS-BORELLA , Baptiste RONAN , Herve MINOUX , Claude BARBERIS , Yves JANIN

IPC分类号： A61K31/4162 , A61P35/00 , C07D487/04 , C12N9/99

CPC分类号： C07D495/04

摘要： Compounds of formula (I), wherein R1 and R3 have the meanings given in the description, said compounds being in all isomeric forms; and salts thereof; processes for the preparation of the compounds and intermediates; compositions containing them, and the use thereof as medicaments, particularly as anti-cancer agents.

摘要翻译： 式（I）化合物，其中R1和R3具有本说明书中给出的含义，所述化合物为所有异构体形式; 及其盐; 制备化合物和中间体的方法; 含有它们的组合物及其作为药物的用途，特别是作为抗癌剂。

2.

发明申请
Hydrazinocarbonyl-thieno[2,3-C]pyrazoles, Process for Preparing Them, Compositions Containing Them and Use Thereof 有权
标题翻译：肼基 - 噻吩并[2,3-C]吡唑，其制备方法，含有它们的组合物及其用途

公开(公告)号：US20080146542A1

公开(公告)日：2008-06-19

申请号：US11846669

申请日：2007-08-29

申请人： Claude BARBERIS , Jean-Christophe CARRY , Gilles DOERFLINGER , Dominique BARBALAT-DAMOUR , Francois CLERC , Herve MINOUX

发明人： Claude BARBERIS , Jean-Christophe CARRY , Gilles DOERFLINGER , Dominique BARBALAT-DAMOUR , Francois CLERC , Herve MINOUX

IPC分类号： A61K31/553 , C07D267/10 , C07D403/14 , A61K31/497 , A61P35/02 , A61P27/06 , A61P17/06 , A61K31/4162 , A61K31/551 , C07D487/04

CPC分类号： C07D495/04

摘要： The present invention concerns hydrazinocarbonyl-thieno[2,3-c]pyrazoles of formula (I): wherein R1, R3, R4, are R5 are as defined in the disclosure; their preparation method, compositions containing the same and their use for the treatment of pathological conditions, in particular as anticancer agents.

摘要翻译： 本发明涉及式（I）的肼基羰基 - 噻吩并[2,3-c]吡唑：其中R 1，R 3，R 4，R 5如本公开所定义; 其制备方法，含有该组合物的组合物及其用于治疗病理状况的用途，特别是作为抗癌剂。

3.

发明申请
1,4-Dihydropyridine-Fused Heterocycles, Process for Preparing the Same, Use and Compositions Containing Them 有权
标题翻译： 1,4-二氢吡啶稠合杂环，其制备方法，含有它们的用途和组合物

公开(公告)号：US20080261969A1

公开(公告)日：2008-10-23

申请号：US12014516

申请日：2008-01-15

申请人： Jacques MAUGER , Anil NAIR , Nina MA , Kirsten BJERGARDE , Bruno FILOCHE-ROMME , Odile ANGOUILLANT-BONIFACE , Serge MIGNANI , Jean-Christophe CARRY , Francois CLERC , Herve MINOUX , Laurent SCHIO , Cecile COMBEAU

发明人： Jacques MAUGER , Anil NAIR , Nina MA , Kirsten BJERGARDE , Bruno FILOCHE-ROMME , Odile ANGOUILLANT-BONIFACE , Serge MIGNANI , Jean-Christophe CARRY , Francois CLERC , Herve MINOUX , Laurent SCHIO , Cecile COMBEAU

IPC分类号： A61K31/5377 , C07D471/12 , A61K31/4353 , C07D471/02 , A61P35/00 , A61K31/519 , C07D295/00

CPC分类号： C07D471/04 , C07D471/14

摘要： This invention relates to compounds of formula (I) to processes for the preparation of such compounds, to pharmaceutical compositions comprising such compounds, and to methods of treatment comprising administering of such compounds.

摘要翻译： 本发明涉及式（I）化合物，其用于制备这些化合物的方法，包含这些化合物的药物组合物，以及涉及治疗方法，包括施用这些化合物。

4.

发明申请
PYRAZOLYLBENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND USE THEREOF 有权
标题翻译：吡唑并苯并咪唑衍生物，包含它们的组合物及其用途

公开(公告)号：US20090197866A1

公开(公告)日：2009-08-06

申请号：US12338176

申请日：2008-12-18

申请人： Marie-Pierre CHERRIER , Eric PARMANTIER , Herve MINOUX , Francois CLERC , Odile ANGOUILLANT-BONIFACE , Maurice BROLLO , Laurent SCHIO

发明人： Marie-Pierre CHERRIER , Eric PARMANTIER , Herve MINOUX , Francois CLERC , Odile ANGOUILLANT-BONIFACE , Maurice BROLLO , Laurent SCHIO

IPC分类号： A61K31/553 , C07D413/14 , A61K31/5377 , A61P35/00

CPC分类号： C07D403/04 , C07D235/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14

摘要： The disclosure relates to compounds of formula (I): wherein R1, R2, R3, R4, and R5 are as defined in the disclosure, to the compositions containing them and to the use thereof as medicaments, in particular as anticancer agents. The disclosure also relates to the process for preparing the compounds of formula (I) and to reaction intermediates.

摘要翻译： 本公开涉及式（I）的化合物：其中R 1，R 2，R 3，R 4和R 5如本公开所定义，含有它们的组合物及其作为药物，特别是作为抗癌剂的用途。本公开还涉及制备式（I）化合物和反应中间体的方法。

5.

发明申请
Novel Benzimidazole and Benzothiazole Derivatives, Method for Preparing Same, Use Thereof as Drugs, Pharmaceutical Compositions and Novel Use Especially as c-MET Inhibitors 失效
标题翻译：新型苯并咪唑和苯并噻唑衍生物，其制备方法，用途为药物，药物组合物和新型用途，特别是作为c-MET抑制剂

公开(公告)号：US20080194555A1

公开(公告)日：2008-08-14

申请号：US12054719

申请日：2008-03-25

申请人： Conception NEMECEK , Francois CLERC

发明人： Conception NEMECEK , Francois CLERC

IPC分类号： A61K31/5377 , C07D235/30 , C07D417/12 , A61K31/4184

CPC分类号： C07D235/30 , C07D277/82

摘要： This invention relates to benzimidazole and benzothiazole compounds of formula (I) to methods of preparing such compounds, pharmaceutical compositions comprising such compounds, and to methods of treatment comprising administering of such compounds.

摘要翻译： 本发明涉及式（I）的苯并咪唑和苯并噻唑化合物与制备这些化合物的方法，包含这些化合物的药物组合物以及包括给予这些化合物的治疗方法。