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    Substance with lipo-oligosaccharide structure capable of acting as plant-specific symbiotic signals, processes for producing them and their applications
    7.
    发明授权
    Substance with lipo-oligosaccharide structure capable of acting as plant-specific symbiotic signals, processes for producing them and their applications 失效
    具有能够作为植物特异性共生信号的脂寡糖结构的物质，其生产方法及其应用

    公开(公告)号：US5549718A

    公开(公告)日：1996-08-27

    申请号：US315491

    申请日：1994-09-30

    申请人： Patrice Lerouge ,  Philippe Roche ,  Catherine Faucher ,  Fabienne Maillet ,  Jean Denarie ,  Jean-Claude Prome ,  Georges Truchet

    发明人： Patrice Lerouge ,  Philippe Roche ,  Catherine Faucher ,  Fabienne Maillet ,  Jean Denarie ,  Jean-Claude Prome ,  Georges Truchet

    IPC分类号： C07H13/06 ,  C12P19/04 ,  A01C1/06 ,  A01H3/04 ,  C12R1/41

    CPC分类号： C07H13/06 ,  C12P19/04 ,  Y10S435/878

    摘要： An essentially pure substance has a structure of a Nod factor or one of its analogues. The Nod factor is characterized by the fact that its biosynthesis is controlled by at least one nodulation gene (nodA,B,C) common to the Rhizobiaceae, in particular to the genera Rhizobium, Bradyrhizobium, Sinorhizobium and Azorhizobium. This substance consists of a lipo-oligosaccharide which is not a derivative of the exopolysaccharides and which has the general formula (I). In formula (I), the Nod factor of which it has the structure is a plant-specific symbiotic signal and is capable of enhancing the capacity of the bacteria of infect the host plant with which it is associated and/or of accelerating the formation of nodules on the host plant with which it is associated and/or of inducing the transcription of symbiotic genes of the leguminoseae. Applications to the treatment of plants and as an active therapeutic agent in humans and animals. G stands for a hexosamine variously substituted, for example by an acetyl group on the nitrogen, a sulphate group, an acetyl group and/or an ether group on oxygen R.sub.1, R.sub.2, R.sub.3, R.sub.5, R.sub.6, R.sub.7, which may be identical or different, stand for H, CH.sub.3 CO--, C.sub.x H.sub.y CO-- where X is a whole number between 0 and 17 and Y is a whole number between 1 and 35, or any other acyl group, for example a carbamyl groups, R.sub.4 stands for a saturated or mono-, di or tri-unsaturated aliphatic chain containing at least 12 carbon atoms and n is a whole number between 1 and 4.

    摘要翻译： 基本上纯的物质具有Nod因子或其类似物之一的结构。 Nod因子的特征在于其生物合成由根瘤菌科共同的至少一个结瘤基因（nodA，B，C）控制，特别是根瘤菌属，Bradyrhizobium，Sinorhizobium和Azorhizobium属。 该物质由不是外多糖的衍生物的脂寡糖组成，具有通式（I）。 在式（I）中，其具有结构的节点因子是植物特异性共生信号，并且能够增强感染与其相关的宿主植物的细菌的能力和/或加速形成 与其相关的宿主植物上的结节和/或诱导豆科的共生基因的转录。 用于治疗植物和作为人类和动物中的活性治疗剂的应用。 G代表各种取代的己糖胺，例如在氧R1，R2，R3，R5，R6，R7上的氮上的乙酰基，硫酸根基团，乙酰基和/或醚基，其可以是相同的或 不同的是，代表H，CH 3 CO-，C x H y CO-，其中X是0和17之间的整数，Y是1和35之间的整数，或任何其它酰基，例如氨基甲酰基，R4代表饱和或 含有至少12个碳原子的单，二或三不饱和脂肪族链，n是1至4之间的整数。