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    Intraluminal medical devices in combination with therapeutic agents
    8.
    发明授权
    Intraluminal medical devices in combination with therapeutic agents 有权
    管腔内医疗器械与治疗剂组合

    公开(公告)号：US08747881B2

    公开(公告)日：2014-06-10

    申请号：US11131720

    申请日：2005-05-18

    申请人： Robert Falotico ,  Pallassana Narayanan

    发明人： Robert Falotico ,  Pallassana Narayanan

    IPC分类号： A61F13/00 ,  A61F2/00 ,  A61F2/06

    CPC分类号： A61F2/06 ,  A61F2/07 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/434 ,  A61L2300/602 ,  C08L27/16 ,  C08L27/20

    摘要： Medical devices may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.

    摘要翻译： 可以涂覆医疗装置以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物，药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 此外，这些治疗药物，药剂和/或化合物可用于促进愈合，包括血块的形成。 此外，可以使用各种聚合物组合来控制来自可植入医疗装置的治疗药物，药剂和/或化合物的洗脱速率。

    Antithrombotic coating for drug eluting medical devices
    10.
    发明授权
    Antithrombotic coating for drug eluting medical devices 有权
    用于药物洗脱医疗器械的抗血栓涂层

    公开(公告)号：US07947302B2

    公开(公告)日：2011-05-24

    申请号：US12334849

    申请日：2008-12-15

    申请人： Robert Falotico ,  Jonathon Z. Zhao

    发明人： Robert Falotico ,  Jonathon Z. Zhao

    IPC分类号： A61F2/06 ,  A61K47/32

    CPC分类号： A61L33/0029 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/61

    摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

    摘要翻译： 可以涂覆医疗装置，特别是可植入医疗装置，以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物，药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 这些治疗药物，药剂或化合物还可以进一步减少生物体对将生物体引入医疗装置的反应。 此外，这些治疗药物，药剂和/或化合物可用于促进愈合，包括血块的形成。 可以使用各种材料和涂覆方法来将药物，试剂或化合物维持在医疗装置上，直到输送和定位。