DEVICE AND METHODS FOR PREPARATION OF PEPTIDES AND PROTEINS SAMPLES FROM SOLUTION
    2.
    发明申请
    DEVICE AND METHODS FOR PREPARATION OF PEPTIDES AND PROTEINS SAMPLES FROM SOLUTION 审中-公开
    用于从溶液中制备肽和蛋白样品的装置和方法

    公开(公告)号:US20100267939A1

    公开(公告)日:2010-10-21

    申请号:US12095643

    申请日:2006-12-06

    IPC分类号: C07K1/22

    摘要: Featured are devices, methods and kits for preparation of samples of peptides and proteins from a solution; more particularly to such devices and methods in which carbon nanotubes are utilized for sample preparation and/or purification of peptide and/or protein samples from a solution. A sample to be treated/processed can comprise proteins, peptides or any other molecule having an amine moiety that can be protonated under low pH, such as, but not limited to, pH 5. Such a sample also can contain contaminants such as salts, detergents, etc. that will be eliminated during the sample preparation/purification process of the present invention. The methods, devices and kits of the present invention advantageously provide for the concentration of the sample, removal of contaminants and ease of manipulation of small liquids without the concomitant loss of sample.

    摘要翻译: 特色是从溶液中制备肽和蛋白质样品的装置,方法和试剂盒; 更具体地涉及其中碳纳米管用于从溶液中制备和/或纯化肽和/或蛋白质样品的这种装置和方法。 待处理/加工的样品可以包含蛋白质,肽或具有胺部分的任何其它分子,其可以在低pH(例如但不限于)pH 5下被质子化。这样的样品还可以含有污染物,例如盐, 在本发明的样品制备/纯化过程中将被消除的洗涤剂等。 本发明的方法,装置和试剂盒有利地提供了样品的浓度,去除污染物和容易操作小液体而没有伴随的样品损失。