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公开(公告)号：US06183696B2
公开(公告)日：2001-02-06
申请号：US09009990
申请日：1998-01-21
申请人： Jerry Elkind , Richard A. Carr , Jose Melendez
发明人： Jerry Elkind , Richard A. Carr , Jose Melendez
IPC分类号： G01N2117
CPC分类号： G01N21/553 , G01N21/05
摘要： A miniaturized sensor (100) that improves the confidence measure of a given sample reading by directing the flow of sample to the sensor/sample interface (117) and thus bringing the sample reliably in contact with the sensor's biosensing film. An inlet flow channel (105) extending from the bottom (125) of the sensor (100) to the sensing surface (120). The inlet channel (105) guides the sample to a cavity 115 formed at a housing surface (120) where it interacts with the film deposit (117). An outlet channel (110) extends from the cavity (115) to the bottom surface (125) and directs the sample outside the device. The light source (58), detector array (68) and interface (54) can be added to the structure providing a fully integrated miniaturized sensor. Various well known methods of manufacturing may be used including mill casting, split molding and double mold processes.
摘要翻译： 一种小型化传感器（100），其通过将样本流引导到传感器/样品界面（117），从而使样品可靠地与传感器的生物传感膜接触来改善给定样品读数的置信度。 从所述传感器（100）的底部（125）延伸到所述感测表面（120）的入口流动通道（105）。 入口通道（105）将样品引导到形成在其与膜沉积物（117）相互作用的壳体表面（120）处的空腔115。 出口通道（110）从空腔（115）延伸到底表面（125）并将样品引导到设备外部。 可以将光源（58），检测器阵列（68）和接口（54）添加到提供完全集成的小型化传感器的结构中。 可以使用各种众所周知的制造方法，包括轧制，分模和双模工艺。
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公开(公告)号：US6024923A
公开(公告)日：2000-02-15
申请号：US313466
申请日：1999-05-17
申请人： Jose Melendez , Richard A. Carr , Diane Arbuthnot
发明人： Jose Melendez , Richard A. Carr , Diane Arbuthnot
CPC分类号： G01N21/645 , G01N21/6428 , G01N2201/022
摘要： An integrated biochemical sensor (200) for detecting the presence of one or more specific samples (240) having a device platform (355) with a light absorbing upper surface and input/output pins (375) is disclosed. An encapsulating housing (357) provides an optical transmissive enclosure which covers the platform (355) and has a layer of fluorescence chemistry on its outer surface (360). The fluorophore is chosen for its molecular properties in the presence of the sample analyte (240). The detector (370), light sources (365, 367, 407, 409) are all coupled to the platform (355) and encapsulated within the housing (357). A filter (375) element is used to block out unwanted light and increase the detector's (370) ability to resolve wanted emission light.
摘要翻译： 公开了一种用于检测具有光吸收上表面和输入/输出销（375）的装置平台（355）的一个或多个特定样品（240）的存在的集成生物化学传感器（200）。 封装壳体（357）提供覆盖平台（355）并且在其外表面（360）上具有一层荧光化学物质的透光外壳。 在样品分析物（240）的存在下，选择荧光团的分子性质。 检测器（370），光源（365,367,407,409）都耦合到平台（355）并且封装在壳体（357）内。 滤光器（375）元件用于阻挡不需要的光，并增加检测器（370）解决所需发射光的能力。
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公开(公告)号：US5922285A
公开(公告)日：1999-07-13
申请号：US942090
申请日：1997-10-01
CPC分类号： G01N21/645 , G01N21/6428 , G01N2201/022
摘要： An integrated biochemical sensor (200) for detecting the presence of one or more specific samples (240) having a device platform (355) with a light absorbing upper surface and input/output pins (375) is disclosed. An encapsulating housing (357) provides an optical transmissive enclosure which covers the platform (355) and has a layer of fluorescence chemistry on its outer surface (360). The fluorophore is chosen for its molecular properties in the presence of the sample analyte (240). The detector (370), light sources (365, 367, 407, 409) are all coupled to the platform (355) and encapsulated within the housing (357). A filter (375) element is used to block out unwanted light and increase the detector's (370) ability to resolve wanted emission light.
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公开(公告)号：US07730944B2
公开(公告)日：2010-06-08
申请号：US11933242
申请日：2007-10-31
IPC分类号： E21B49/00
CPC分类号： E21B47/1025 , E21B34/10 , E21B49/008 , Y10T29/49826
摘要： A multi-functional completion tool which may be lowered into a wellbore coupled to a length of tubing, and then utilized to test various lengths of the tubing at pressure. The tool may also function as a positive plug and may also be used to set the packer, and is also useable as a tubing self-filling tool. Various retention elements are disposed within the tool and configured to release at predetermined pressures, or within predetermined ranges of pressure, thereby transforming the tool from a first configuration to a second configuration depending on the desired function. The tool may also contain a pressure-regulating assembly for regulating the differential pressure across the assembly. The tool may also include an indicator assembly for confirming that the tool has entered a plugging configuration, typically by altering a pressure within the tubing, such alteration being detectible at a surface location.
摘要翻译： 一种多功能完井工具，其可以下降到与一段管道相连的井筒中，然后用于在压力下测试管道的各种长度。 该工具还可以用作积极的塞子并且也可用于设置封隔器，并且也可用作管道自填充工具。 各种保持元件设置在工具内并且构造成在预定压力或预定压力范围内释放，从而根据期望的功能将工具从第一构型转变成第二构型。 该工具还可以包含用于调节整个组件上的压差的压力调节组件。 该工具还可以包括用于确认工具已经进入堵塞构型的指示器组件，通常通过改变管道内的压力，这种变化在表面位置是可检测的。
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公开(公告)号：US08606344B2
公开(公告)日：2013-12-10
申请号：US12433597
申请日：2009-04-30
申请人： John Michael DiMaio , James Watson , Jose Melendez , Roma Moza , Harry Tibbals
发明人： John Michael DiMaio , James Watson , Jose Melendez , Roma Moza , Harry Tibbals
IPC分类号： A61B5/00
CPC分类号： A61G7/1025 , A61B5/00 , A61B5/0059 , A61B5/0077 , A61B5/447 , A61B5/6887 , A61B5/704 , A61B6/04 , A61B6/56 , A61B2576/00 , A61G7/015 , A61G7/05769 , A61G2210/20 , G01N21/8851 , G06F19/00 , G16H40/63
摘要： The present invention includes an integrated system and methods for patient treatment, the system includes a hospital bed; a plurality of patient diagnostic and treatment devices connected to a network, wherein each of the devices can communicate to a network and exchange information with the network about the care of a patient; and a processor accessible adjacent to the bed and connected to the network to integrate information obtained from the devices through the network with one or more additional sources of information databases, wherein the processor can communicate to one or more patient treatment devices either directly or via the network and the processor directs the one or more patient treatment devices to change the treatment of the patient.
摘要翻译： 本发明包括用于患者治疗的综合系统和方法，所述系统包括医院病床; 连接到网络的多个患者诊断和治疗设备，其中每个设备可以与网络通信并且与网络交换关于患者护理的信息; 以及处理器，其可与所述床相邻并且连接到所述网络，以将通过所述网络从所述设备获得的信息与一个或多个附加的信息数据源集成，其中所述处理器可以直接地或经由所述网络与一个或多个患者治疗设备通信 网络并且处理器引导一个或多个患者治疗装置改变患者的治疗。
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公开(公告)号：US07203425B1
公开(公告)日：2007-04-10
申请号：US09620943
申请日：2000-07-21
申请人： Robert Keller , Jose Melendez
发明人： Robert Keller , Jose Melendez
IPC分类号： H04B10/00
CPC分类号： H04B10/1143 , H04B10/40
摘要： An optical, line-of-sight modem. The modem includes a micro-mirror assembly including a micro-mirror and including an actuator for providing rotational movement to the micro-mirror, the micro-mirror being controllable by predetermined control signals. The modem includes a source of electronic data signals, and a source of light having a narrow beam of light directed at the micro-mirror. Means are provided for converting the electronic data signals to optical signals modulating the beam of light. Means are also provided for controlling the micro-mirror so as to maintain the micro-mirror in a predetermined position for data communication.
摘要翻译： 光学视距调制解调器。 调制解调器包括微反射镜组件，其包括微镜并且包括用于向微镜提供旋转运动的致动器，微镜可由预定的控制信号控制。 调制解调器包括电子数据信号源和具有指向微镜的窄光束的光源。 提供了用于将电子数据信号转换成调制光束的光信号的装置。 还提供了用于控制微反射镜以便将微反射镜保持在用于数据通信的预定位置的装置。
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公开(公告)号：US20090275808A1
公开(公告)日：2009-11-05
申请号：US12433597
申请日：2009-04-30
申请人： John Michael DiMaio , James Watson , Jose Melendez , Roma Moza , Harry Tibbals
发明人： John Michael DiMaio , James Watson , Jose Melendez , Roma Moza , Harry Tibbals
CPC分类号： A61G7/1025 , A61B5/00 , A61B5/0059 , A61B5/0077 , A61B5/447 , A61B5/6887 , A61B5/704 , A61B6/04 , A61B6/56 , A61B2576/00 , A61G7/015 , A61G7/05769 , A61G2210/20 , G01N21/8851 , G06F19/00 , G16H40/63
摘要： The present invention includes an integrated system and methods for patient treatment, the system includes a hospital bed; a plurality of patient diagnostic and treatment devices connected to a network, wherein each of the devices can communicate to a network and exchange information with the network about the care of a patient; and a processor accessible adjacent to the bed and connected to the network to integrate information obtained from the devices through the network with one or more additional sources of information databases, wherein the processor can communicate to one or more patient treatment devices either directly or via the network and the processor directs the one or more patient treatment devices to change the treatment of the patient.
摘要翻译： 本发明包括用于患者治疗的综合系统和方法，该系统包括医院病床; 连接到网络的多个患者诊断和治疗设备，其中每个设备可以与网络通信并且与网络交换关于患者护理的信息; 以及处理器，其可与所述床相邻并且连接到所述网络，以将通过所述网络从所述设备获得的信息与一个或多个附加的信息数据源集成，其中所述处理器可以直接地或经由所述网络与一个或多个患者治疗设备通信 网络并且处理器引导一个或多个患者治疗装置改变患者的治疗。
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公开(公告)号：US08838211B2
公开(公告)日：2014-09-16
申请号：US12433639
申请日：2009-04-30
申请人： Jose Melendez , James Watson , John Michael DiMaio , Roma Moza
发明人： Jose Melendez , James Watson , John Michael DiMaio , Roma Moza
CPC分类号： A61G7/1025 , A61B5/00 , A61B5/0059 , A61B5/0077 , A61B5/445 , A61B5/447 , A61B5/6887 , A61B6/04 , A61B6/56 , A61B2576/00 , A61G7/015 , A61G2210/20 , G01N21/8851 , G06F19/00 , G16H40/63
摘要： The present invention is a multi-wavelength diagnostic imager. In one embodiment, the present invention includes an apparatus and method for noninvasive evaluation of a target versus a non-target, comprising: one or more light sources having at least one emission spectra directed at the target wherein the position, orientation and intensity of light sources is varied to control near-surface reflectance and are directed at less than the entire target; and one or more detectors positioned to capture light reflected from the target into two or more spatial images of the target at two or more times, wherein the spatial images are used to distinguish between the target and the non-target.
摘要翻译： 本发明是多波长诊断成像器。 在一个实施例中，本发明包括用于非侵入性评估靶与非靶的装置和方法，包括：一个或多个光源，其具有指向靶的至少一个发射光谱，其中光的位置，取向和强度 来源变化以控制近地表反射率并且指向小于整个目标; 以及一个或多个检测器，定位成将来自目标反射的光在两次或更多次捕获到目标的两个或更多个空间图像中，其中，空间图像用于区分目标和非目标。
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公开(公告)号：US20140090173A1
公开(公告)日：2014-04-03
申请号：US14098242
申请日：2013-12-05
申请人： John Michael DiMaio , James Watson , Jose Melendez , Roma Moza , Harry Tibbals
发明人： John Michael DiMaio , James Watson , Jose Melendez , Roma Moza , Harry Tibbals
CPC分类号： A61G7/1025 , A61B5/00 , A61B5/0059 , A61B5/0077 , A61B5/0555 , A61B5/447 , A61B5/6887 , A61B5/704 , A61B6/04 , A61B6/56 , A61B2576/00 , A61G7/015 , A61G7/05769 , A61G2210/20 , G01N21/8851 , G16H40/63
摘要： The present invention includes an integrated system and methods for patient treatment, the system includes a hospital bed; a plurality of patient diagnostic and treatment devices connected to a network, wherein each of the devices can communicate to a network and exchange information with the network about the care of a patient; and a processor accessible adjacent to the bed and connected to the network to integrate information obtained from the devices through the network with one or more additional sources of information databases, wherein the processor can communicate to one or more patient treatment devices either directly or via the network and the processor directs the one or more patient treatment devices to change the treatment of the patient.
摘要翻译： 本发明包括用于患者治疗的综合系统和方法，所述系统包括医院病床; 连接到网络的多个患者诊断和治疗设备，其中每个设备可以与网络通信并且与网络交换关于患者护理的信息; 以及处理器，其可与所述床相邻并且连接到所述网络，以将通过所述网络从所述设备获得的信息与一个或多个附加的信息数据源集成，其中所述处理器可以直接地或经由所述网络与一个或多个患者治疗设备通信 网络并且处理器引导一个或多个患者治疗装置改变患者的治疗。
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公开(公告)号：US20090275841A1
公开(公告)日：2009-11-05
申请号：US12433639
申请日：2009-04-30
申请人： Jose Melendez , James Watson , John Michael DiMaio , Roma Moza
发明人： Jose Melendez , James Watson , John Michael DiMaio , Roma Moza
IPC分类号： A61B6/00
CPC分类号： A61G7/1025 , A61B5/00 , A61B5/0059 , A61B5/0077 , A61B5/445 , A61B5/447 , A61B5/6887 , A61B6/04 , A61B6/56 , A61B2576/00 , A61G7/015 , A61G2210/20 , G01N21/8851 , G06F19/00 , G16H40/63
摘要： The present invention is a multi-wavelength diagnostic imager. In one embodiment, the present invention includes an apparatus and method for noninvasive evaluation of a target versus a non-target, comprising: one or more light sources having at least one emission spectra directed at the target wherein the position, orientation and intensity of light sources is varied to control near-surface reflectance and are directed at less than the entire target; and one or more detectors positioned to capture light reflected from the target into two or more spatial images of the target at two or more times, wherein the spatial images are used to distinguish between the target and the non-target.
摘要翻译： 本发明是多波长诊断成像器。 在一个实施例中，本发明包括用于非侵入性评估靶与非靶的装置和方法，包括：一个或多个光源，其具有指向靶的至少一个发射光谱，其中光的位置，取向和强度 来源变化以控制近地表反射率并且指向小于整个目标; 以及一个或多个检测器，定位成将来自目标反射的光在两次或更多次捕获到目标的两个或更多个空间图像中，其中，空间图像用于区分目标和非目标。
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