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    Radiation centering catheters
    1.
    发明授权
    Radiation centering catheters 失效
    辐射定心导管

    公开(公告)号：US06224535B1

    公开(公告)日：2001-05-01

    申请号：US09024666

    申请日：1998-02-17

    申请人： Jessica G. Chiu ,  Eric D. Peterson

    发明人： Jessica G. Chiu ,  Eric D. Peterson

    IPC分类号： A61N500

    CPC分类号： A61N5/1002 ,  A61M25/10 ,  A61N2005/1003

    摘要： The invention is directed to a radiation delivery catheter assembly for maintaining patency of a body lumen for a period of time sufficient to allow delivery of a radiation source to the body lumen. The catheter utilizes an inflatable region which maintains and centers the catheter in the body lumen. The catheter may include a perfusion lumen for supplying oxygenated blood to tissue located downstream from the catheter when the inflatable region is expanded in the body lumen. The inflatable region can be made up of a plurality of balloon segments which help center the radiation source, even if placed on a curved section of the body lumen. Embodiments of the invention include a catheter design which utilizes “rapid exchange” features and a dual therapeutic catheter which is capable of dilating a stenosed region of the body lumen prior to the administration of the radiation treatment. A two-piece protective sheath is used to protect the radiation source from bodily fluids.

    摘要翻译： 本发明涉及一种辐射递送导管组件，用于维持体腔通畅一段足以使辐射源传送至体腔的时间。 该导管使用可将导管保持并居中在体腔内的可充气区域。 当可膨胀区域在体腔内扩张时，导管可包括用于将氧合血液供应到位于导管下游的组织的灌注腔。 可膨胀区域可以由多个气囊段组成，即使放置在体腔的弯曲部分上也有助于使辐射源居中。 本发明的实施例包括利用“快速交换”特征的导管设计和能够在施用放射治疗之前扩张体腔的狭窄区域的双重治疗导管。 使用两片保护套来保护辐射源免受体液的伤害。

    Radiopaque marker for a catheter and method of making
    2.
    发明授权
    Radiopaque marker for a catheter and method of making 有权
    导管的不透射线标记和制作方法

    公开(公告)号：US06761708B1

    公开(公告)日：2004-07-13

    申请号：US09703518

    申请日：2000-10-31

    申请人： Jessica G. Chiu ,  Arlene S. Yang

    发明人： Jessica G. Chiu ,  Arlene S. Yang

    IPC分类号： A61M2500

    CPC分类号： A61M25/0009 ,  A61M25/0108 ,  A61M2025/1079

    摘要： A catheter having a radiopaque marker and a method of forming the radiopaque marker on the catheter component. One embodiment of the invention is directed to a method of making a radiopaque marker on a catheter component comprising depositing a first layer of radiopaque material onto at least a section of the catheter component, which in a presently preferred embodiment is deposited by thin film deposition, and electroplating a second layer of radiopaque material onto an outer surface of the first layer of radiopaque material. In one embodiment of the invention, a catheter component has a radiopaque marker comprising a first layer of radiopaque material, and a second layer of radiopaque material on the first layer having a thickness greater than the thickness of the first layer. In another embodiment of the invention, a first layer of radiopaque material comprises a blend of polymeric material and radiopaque material and a second layer of radiopaque material is electroplated onto the blended first layer. The radiopaque marker of the invention may be on a variety of catheter components including a catheter shaft or a balloon on a balloon catheter.

    摘要翻译： 具有不透射线标记的导管和在导管部件上形成不透射线标记的方法。 本发明的一个实施例涉及一种在导管部件上制造不透射线的标记的方法，包括将第一层不透射线材料沉积在导管部件的至少一部分上，在目前优选的实施例中，通过薄膜沉积沉积， 并将第二层不透射线材料电镀在第一层不透射线材料的外表面上。 在本发明的一个实施例中，导管部件具有包括第一层不透射线材料的不透射线标记，第一层上的第二层不透射线材料的厚度大于第一层的厚度。 在本发明的另一个实施例中，第一层不透射线材料包括聚合材料和不透射线材料的共混物，并且第二层不透射线材料电镀在混合的第一层上。 本发明的不透射线标记可以在各种导管部件上，包括导管轴或球囊导管上的球囊。

    Radiation delivery catheter with a spring wire centering mechanism
    5.
    发明授权
    Radiation delivery catheter with a spring wire centering mechanism 失效
    具有弹簧丝定心机构的辐射输送导管

    公开(公告)号：US6159139A

    公开(公告)日：2000-12-12

    申请号：US24078

    申请日：1998-02-17

    申请人： Jessica G. Chiu

    发明人： Jessica G. Chiu

    IPC分类号： A61F2/958 ,  A61M36/04 ,  A61N5/10 ,  A61M25/10 ,  A61M29/00

    CPC分类号： A61M25/10 ,  A61N5/1002 ,  A61M2025/1047 ,  A61N2005/1003

    摘要： The invention is directed to a radiation delivery catheter assembly having blood perfusion capability suitable for maintaining patency of a body lumen for a period of time sufficient to allow delivery of a radiation source to the body lumen. The catheter assembly includes a spring wire centering mechanism which can be deployed between a retracted and expanded position. In the expanded position, the spring wire centering mechanism contacts a portion of the body lumen and centers a radiation source within the body lumen. In one particular embodiment, movable structural elements (spring wire legs) contact and center the adjacent portion of the catheter body within the body lumen when placed in the expanded position. In the retracted position, the spring wire mechanism is collapsed to a small profile to enable the catheter assembly to reach small diameter body lumens, such as distal coronary arteries. The spring wire centering mechanism is deployed between the retracted and expanded positions utilizing a retractable sheath which extends over the catheter body in a coaxial arrangement. This retractable sheath is movable along the length of the elongated catheter body and is designed to cover the spring wire centering mechanism to maintain it in the retracted position until the mechanism is to be deployed within the body lumen. When the retractable sheath is retracted to expose the spring wire centering mechanism, the resiliency of the spring wire legs moves the mechanism back to the expanded position.

    摘要翻译： 本发明涉及具有适于维持体腔通畅一段时间的血液灌注能力的辐射递送导管组件，该时间长度足以使辐射源传送到体腔。 导管组件包括弹簧丝定心机构，其可以在缩回位置和展开位置之间展开。 在扩展位置，弹簧导线定心机构接触体腔的一部分并使体腔内的辐射源居中。 在一个特定实施例中，当放置在扩张位置时，可移动结构元件（弹簧线腿）在导管主体的相邻部分内接触并居中。 在缩回位置，弹簧丝机构折叠成小的轮廓，以使得导管组件能够到达小直径体腔，例如冠状动脉远端。 弹簧丝定心机构利用可同轴布置在导管主体上延伸的可缩回护套来展开在缩回位置和扩展位置之间。 该伸缩护套可沿着细长的导管主体的长度移动，并被设计成覆盖弹簧丝定心机构以将其保持在缩回的位置，直到该机构被展开在体腔中。 当伸缩护套缩回以暴露弹簧丝定心机构时，弹簧丝腿的弹性使机构回到扩展位置。