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    Medical prostheses having bundled and non-bundled regions
    3.
    发明授权
    Medical prostheses having bundled and non-bundled regions 有权

    公开(公告)号：US10265200B2

    公开(公告)日：2019-04-23

    申请号：US13814179

    申请日：2010-08-10

    申请人： Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    发明人： Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    IPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/89

    摘要： The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

    MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS
    4.
    发明申请
    MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS 审中-公开
    具有组合和非完整区域的医疗前景

    公开(公告)号：US20130211497A1

    公开(公告)日：2013-08-15

    申请号：US13814179

    申请日：2010-08-10

    申请人： Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    发明人： Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    IPC分类号： A61F2/82

    CPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/075 ,  A61F2250/0017 ,  A61F2250/0028

    摘要： The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

    摘要翻译： 本实施例提供具有相对低的传送轮廓的腔内假体，例如支架移植物。 在一个实施例中，假体包括膜和至少一个具有收缩和扩张状态的支架，其中支架联接到膜并且保持开放状态处于膨胀状态。 假体还可以包括沿着假体的长度和圆周布置在预定位置处的选择性地定向的轴向和/或周向纤维。 圆周和/或轴向纤维的增加的人口密度可以设置在其中至少一个支架部分附接到膜的区域中，或者在施加在内腔假体上的较高生理负荷的区域中。 沿着假体的长度和周长的预定位置选择性地定向轴向纤维和周向纤维，但不是沿着整个假体连续地定向，从而显着减少由于移植材料的减少导致的输送轮廓。

    S-shaped stent design
    6.
    发明授权
    S-shaped stent design 有权
    S形支架设计

    公开(公告)号：US07655033B2

    公开(公告)日：2010-02-02

    申请号：US11297913

    申请日：2005-12-08

    申请人： Neal E. Fearnot ,  Blayne A. Roeder ,  Alan R. Leewood ,  Jichao Sun

    发明人： Neal E. Fearnot ,  Blayne A. Roeder ,  Alan R. Leewood ,  Jichao Sun

    IPC分类号： A61F2/06

    CPC分类号： A61F2/82 ,  A61F2/91 ,  A61F2250/0037 ,  A61F2250/0039

    摘要： A variable curvature stent limb is disclosed herein. A stent derived from a plurality of these variable curvature stent limbs may be highly compressible, such that it is compatible with a low-profile delivery device. This stent may be useful over a wider range of body vessel diameters and may possess a greater fatigue life, since this stent may provide a more controlled constant radial force.

    摘要翻译： 本文公开了一种可变曲率支架肢体。 衍生自多个这些可变曲率支架肢体的支架可以是高度可压缩的，使得其与低调输送装置兼容。 该支架可以在更宽范围的体血管直径上有用，并且可以具有更大的疲劳寿命，因为该支架可以提供更受控制的恒定径向力。

    Method of promoting cell proliferation and ingrowth by injury to the native tissue
    8.
    发明授权
    Method of promoting cell proliferation and ingrowth by injury to the native tissue 有权
    通过损伤天然组织促进细胞增殖和向内生长的方法

    公开(公告)号：US07815687B2

    公开(公告)日：2010-10-19

    申请号：US12337163

    申请日：2008-12-17

    申请人： Clinton D. Bahler ,  Alan R. Leewood ,  Jichao Sun

    发明人： Clinton D. Bahler ,  Alan R. Leewood ,  Jichao Sun

    IPC分类号： A61F2/06 ,  A61F2/00

    CPC分类号： A61F2/91 ,  A61F2002/0086 ,  A61F2220/0008 ,  A61F2220/0016 ,  Y10S623/901

    摘要： The present invention relates to methods of treating tissue of the human body, specially, methods of promoting cell proliferation and ingrowth around implantable medical devices. The methods include inserting an apparatus comprising asperities adapted to injure native tissue at a desired anchoring location, injuring the native tissue at the desired anchoring location with the apparatus to initiate an injury response in the native tissue to thereby promote cell proliferation and ingrowth; and implanting the medical device at the treatment location.

    摘要翻译： 本发明涉及治疗人体组织的方法，特别是促进可植入医疗器械周围的细胞增殖和向内生长的方法。 所述方法包括插入装置，其包括适于在期望的锚固位置处伤害天然组织的凹凸，用设备在期望的锚定位置损伤天然组织以在天然组织中引发损伤反应，从而促进细胞增殖和向内生长; 以及将医疗装置植入治疗位置。