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    COATED MEDICAL DEVICES AND METHODS
    1.
    发明申请
    COATED MEDICAL DEVICES AND METHODS 审中-公开
    涂层医疗器械及方法

    公开(公告)号：US20120116503A1

    公开(公告)日：2012-05-10

    申请号：US13383567

    申请日：2010-07-13

    Applicant: David D. Grewe ,  Kenneth Haselby ,  Keith Milner

    Inventor： David D. Grewe ,  Kenneth Haselby ,  Keith Milner

    IPC: A61F2/82 ,  B23P11/00 ,  B23P25/00

    CPC classification number: A61L31/14 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/075 ,  A61L31/082 ,  Y10T29/49826 ,  Y10T29/49885

    Abstract: The invention relates to medical device systems that include a delivery instrument comprising a sheath having an abluminal surface and a luminal surface; a radially-expandable frame disposed at least partially within the sheath, the frame having an abluminal surface at least partially in contact with the luminal surface of the sheath, and a luminal surface defining a sub-stantially cylindrical lumen; and a fine powder coating disposed on at least one of the abluminal surface of the frame and the luminal surface of the sheath. The invention also relates to methods of manufacturing, loading, and delivering the coated medical devices.

    Abstract translation: 本发明涉及医疗装置系统，其包括输送器械，该输送器械包括具有腔内表面和腔表面的护套; 至少部分地设置在所述护套内的可径向扩张的框架，所述框架具有至少部分地与所述护套的所述管腔表面接触的腔内表面，以及限定基本上圆柱形的管腔的管腔表面; 以及细粉末涂层，其设置在框架的外侧表面和护套的管腔表面中的至少一个上。 本发明还涉及制造，加载和递送涂覆的医疗装置的方法。

    Medical prostheses having bundled and non-bundled regions
    2.
    发明授权
    Medical prostheses having bundled and non-bundled regions 有权

    公开(公告)号：US10265200B2

    公开(公告)日：2019-04-23

    申请号：US13814179

    申请日：2010-08-10

    Applicant: Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    Inventor： Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    IPC: A61F2/82 ,  A61F2/07 ,  A61F2/89

    Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

    Magnetically Actuated Gating Devices, Systems, Kits, and Methods
    3.
    发明申请
    Magnetically Actuated Gating Devices, Systems, Kits, and Methods 审中-公开
    磁驱动门控器件，系统，套件和方法

    公开(公告)号：US20160113654A1

    公开(公告)日：2016-04-28

    申请号：US14924188

    申请日：2015-10-27

    Applicant: Jarin Kratzberg ,  Keith Milner ,  Sara Sherman ,  Adam Shields

    Inventor： Jarin Kratzberg ,  Keith Milner ,  Sara Sherman ,  Adam Shields

    IPC: A61B17/122

    CPC classification number: A61B17/122 ,  A61B17/132 ,  A61B2017/00411 ,  A61B2017/00876

    Abstract: Magnetically actuated gating devices, magnetically actuated gating systems, magnetically actuated gating kits, and methods of treatment using a magnetically actuated gating device are described herein. An example embodiment of a magnetically actuated gating device comprises a housing, a rotatable member, a compression member, and a membrane. The rotatable member has a first magnetic field that is configured to interact with a second magnetic field produced by an external element to move the rotatable member between a first position and a second position.

    Abstract translation: 本文描述了磁致动门控装置，磁力驱动门控系统，磁力驱动的门控套件和使用磁力驱动的门控装置的处理方法。 磁力驱动的门控装置的示例性实施例包括壳体，可旋转构件，压缩构件和膜。 可旋转构件具有第一磁场，其被配置为与由外部元件产生的第二磁场相互作用以在第一位置和第二位置之间移动可旋转构件。

    ENDOLUMINAL PROSTHESIS
    4.
    发明申请
    ENDOLUMINAL PROSTHESIS 审中-公开
    内分泌疾病

    公开(公告)号：US20140081386A1

    公开(公告)日：2014-03-20

    申请号：US13618356

    申请日：2012-09-14

    Applicant: Kenneth A. Haselby ,  Keith Milner ,  Shruti Mishra ,  Sara M. Sherman

    Inventor： Kenneth A. Haselby ,  Keith Milner ,  Shruti Mishra ,  Sara M. Sherman

    IPC: A61F2/06 ,  B29C47/06

    CPC classification number: A61F2/07 ,  A61F2/915 ,  A61F2002/072 ,  A61F2002/91575 ,  A61F2240/001 ,  A61F2250/0036

    Abstract: An endoluminal prosthesis for placement within a body vessel may include a tubular support structure including a proximal end segment, a distal end segment, an intermediate segment positioned between the proximal end segment and the distal end segment, a lumen extending longitudinally within the support structure, a luminal surface, and an abluminal surface opposite the luminal surface. The prosthesis may include a first layer of nonwoven electrospun fibers positioned on the luminal surface of the support structure. The prosthesis may include a second layer of nonwoven electrospun fibers positioned on the abluminal surface of the support structure. At least one of the proximal end segment or the distal end segment of the support structure may be encapsulated within a covering including the first layer of nonwoven electrospun fibers and the second layer of nonwoven electrospun fibers. The intermediate segment of the support structure may be unencapsulated within the covering.

    Abstract translation: 用于放置在体容器内的腔内假体可以包括管状支撑结构，其包括近端段，远端段，位于近端段和远端段之间的中间段，在支撑结构内纵向延伸的腔， 管腔表面和与腔表面相对的腹膜表面。 假体可以包括位于支撑结构的腔表面上的第一非织造电纺纤维层。 假体可以包括位于支撑结构的外侧表面上的第二非织造电纺纤维层。 支撑结构的近端段或远端段中的至少一个可以封装在包括非织造电纺纤维的第一层和非织造电纺纤维的第二层的覆盖物内。 支撑结构的中间段可以在封套内未被包封。

    MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS
    5.
    发明申请
    MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS 审中-公开
    具有组合和非完整区域的医疗前景

    公开(公告)号：US20130211497A1

    公开(公告)日：2013-08-15

    申请号：US13814179

    申请日：2010-08-10

    Applicant: Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    Inventor： Steven J. Charlebois ,  William Kurt Dierking ,  Matthew S. Huser ,  Keith Milner ,  Jichao Sun

    IPC: A61F2/82

    CPC classification number: A61F2/82 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/075 ,  A61F2250/0017 ,  A61F2250/0028

    Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

    Abstract translation: 本实施例提供具有相对低的传送轮廓的腔内假体，例如支架移植物。 在一个实施例中，假体包括膜和至少一个具有收缩和扩张状态的支架，其中支架联接到膜并且保持开放状态处于膨胀状态。 假体还可以包括沿着假体的长度和圆周布置在预定位置处的选择性地定向的轴向和/或周向纤维。 圆周和/或轴向纤维的增加的人口密度可以设置在其中至少一个支架部分附接到膜的区域中，或者在施加在内腔假体上的较高生理负荷的区域中。 沿着假体的长度和周长的预定位置选择性地定向轴向纤维和周向纤维，但不是沿着整个假体连续地定向，从而显着减少由于移植材料的减少导致的输送轮廓。

    Anti-adhesive surface treatments
    9.
    发明申请
    Anti-adhesive surface treatments 审中-公开
    防粘表面处理

    公开(公告)号：US20050228491A1

    公开(公告)日：2005-10-13

    申请号：US11103302

    申请日：2005-04-11

    Applicant: Alan Snyder ,  Christopher Siedlecki ,  Keith Milner

    Inventor： Alan Snyder ,  Christopher Siedlecki ,  Keith Milner

    IPC: A61F2/00 ,  A61F2/02 ,  A61F2/06 ,  B29C33/40

    CPC classification number: A61F2/0077 ,  A61F2/06 ,  A61F2002/009 ,  B29C33/405

    Abstract: A surface providing reduced adhesion to formed elements, having an element dimension such as formed element diameter, has a plurality of topographic features. The topographic features have a feature dimension less than the dimension of the formed element so as to reduce the accessible area of the surface available to the formed element for adhesion to the surface. The topographic features may include protrusions, such as pillars.

    Abstract translation: 提供具有诸如成形元件直径的元件尺寸的成形元件降低的粘合力的表面具有多个地形特征。 地形特征具有小于所形成元件的尺寸的特征尺寸，以便减少所形成的元件可用于粘附到表面的表面的可访问区域。 地形特征可以包括突起，例如柱。

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