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1.发明授权Preparation of preserved, non-infectious control cell for use in the identification of a disease through blood testing 失效制备用于通过血液检测鉴定疾病的保存的非感染性对照细胞
公开(公告)号：US5763204A
公开(公告)日：1998-06-09
申请号：US644993
申请日：1996-05-28
IPC分类号： G01N33/96 , G01N33/53 , G01N33/555 , G01N33/567
CPC分类号： G01N33/96 , G01N2496/05
摘要： Preparation of non-infectious control cells from normal, non-infectious, non-disease altered blood by depletion or augmentation of one or more cell types found in normal blood to reflect a specific disease state. The control cells so produced are preserved and thereafter reconstituted for use in immunological assays.
摘要翻译： 通过消耗或增加正常血液中发现的一种或多种细胞类型从正常的非传染性非疾病改变的血液制备非感染性对照细胞以反映特定疾病状态。 保存如此产生的对照细胞，然后重构用于免疫测定。
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2.发明授权Preserved, non-infectious control cell for use in the identification of a disease through blood testing 失效用于通过血液检测鉴定疾病的保存的非感染性对照细胞
公开(公告)号：US5342754A
公开(公告)日：1994-08-30
申请号：US944678
申请日：1992-09-14
IPC分类号： G01N33/49 , A01N1/02 , C12N5/08 , C12N5/10 , C12Q1/64 , G01N33/53 , G01N33/569 , G01N33/96 , G01N31/00
CPC分类号： G01N33/96 , G01N2496/05 , Y10T436/101666
摘要： The invention describes the preparation of non-infectious control cells from normal, non-infectious, non-disease altered blood by depletion or augmentation of one or more cell types found in normal blood to reflect a specific disease state. The control cells so produced are preserved and thereafter reconstituted for use in immunological assays.
摘要翻译： 本发明描述了通过在正常血液中发现的一种或多种细胞类型的消耗或增加来反映正常的，非传染性的非疾病改变的血液中非感染性对照细胞的制备以反映特定的疾病状态。 保存如此产生的对照细胞，然后重构用于免疫测定。
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3.发明授权Preserved, non-infectious control cells prepared by the modulation or modification of normal leukocytes 失效通过调节或修饰正常白细胞制备的保存的非传染性对照细胞
公开(公告)号：US5861311A
公开(公告)日：1999-01-19
申请号：US681731
申请日：1996-07-29
IPC分类号： G01N33/49 , C12N5/08 , G01N1/00 , G01N1/28 , G01N1/42 , G01N15/14 , G01N33/483 , G01N33/50 , G01N33/53 , G01N33/569 , C12N5/00 , G01N31/00 , G01N33/567
CPC分类号： G01N33/56972 , G01N1/42 , G01N33/5005 , G01N2001/2893 , Y10T436/101666
摘要： The invention describes the preparation of preserved, non-infectious control cells. The control cells are prepared by modification, activation or otherwise changing selected normal leukocyte cells, tissue culture cells or zenogenic transplants in immunosuppressed animals to have characteristics of abnormal cells or by the addition of cells from an established cell line, which has been similarly modified or activated, to a normal leukocyte population. The preferred method of preserving the control cells is by lyophilization using an isotonic 10% trehalose solution.
摘要翻译： 本发明描述了保存的非感染性对照细胞的制备。 控制细胞通过修饰，活化或以其它方式改变免疫抑制动物中选定的正常白细胞细胞，组织培养细胞或天青移植来制备，以具有异常细胞的特征或通过从建立的细胞系添加已经类似地修饰的细胞系的细胞 激活，正常白细胞群体。 保存对照细胞的优选方法是使用等渗10％海藻糖溶液冻干。
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4.发明授权Preserved, non-infectious control cells prepared by the modulation or modification of cultured cells 失效通过调节或修饰培养细胞制备的保存的非传染性对照细胞
公开(公告)号：US5622855A
公开(公告)日：1997-04-22
申请号：US378840
申请日：1995-04-10
IPC分类号： G01N33/49 , C12N5/08 , G01N1/00 , G01N1/28 , G01N1/42 , G01N15/14 , G01N33/483 , G01N33/50 , G01N33/53 , G01N33/569 , A01N1/02 , G01N31/00
CPC分类号： G01N33/56972 , G01N1/42 , G01N33/5005 , G01N2001/2893 , Y10T436/101666
摘要： The invention describes the preparation of preserved, non-infectious control cells. The control cells are prepared by modification, activation or otherwise changing selected normal leukocyte cells, tissue culture cells or zenogenic transplants in immunosuppressed animals to have characteristics of abnormal cells or by the addition of cells from an established cell line, which have been similarly modified or activated, to a normal leukocyte population. The preferred method of preserving the control cells is by lyophilization using an isotonic 10% trehalose solution.
摘要翻译： 本发明描述了保存的非感染性对照细胞的制备。 控制细胞是通过修饰，活化或以其它方式改变免疫抑制动物中的选择的正常白细胞细胞，组织培养细胞或天青移植来制备的，以具有异常细胞的特征或通过添加来自建立的细胞系的细胞，其已被类似地修饰或 激活，正常白细胞群体。 保存对照细胞的优选方法是使用等渗10％海藻糖溶液冻干。
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5.发明授权Preserved, non-infectious control cells prepared by the modulation or modification of normal cells 失效通过调节或修饰正常细胞制备的保存的非感染性对照细胞
公开(公告)号：US5409826A
公开(公告)日：1995-04-25
申请号：US73937
申请日：1993-06-08
IPC分类号： G01N33/49 , C12N5/08 , G01N1/00 , G01N1/28 , G01N1/42 , G01N15/14 , G01N33/483 , G01N33/50 , G01N33/53 , G01N33/569 , A01N1/02 , G01N31/00
CPC分类号： G01N33/56972 , G01N1/42 , G01N33/5005 , G01N2001/2893 , Y10T436/101666
摘要： The invention describes the preparation of preserved, non-infectious control cells. The control cells are prepared by modification, activation or otherwise changing selected normal leukocyte cells, tissue culture cells or zenogenic transplants in immunosuppressed animals to have characteristics of abnormal cells or by the addition of cells from an established cell line, which has been similarly modified or activated, to a normal leukocyte population. The preferred method of preserving the control cells is by lyophilization using an isotonic 10% trehalose solution.
摘要翻译： 本发明描述了保存的非感染性对照细胞的制备。 控制细胞通过修饰，活化或以其它方式改变免疫抑制动物中选定的正常白细胞细胞，组织培养细胞或天青移植而制备，以具有异常细胞的特征或通过从建立的细胞系添加已经类似地修饰的细胞系的细胞， 激活，正常白细胞群体。 保存对照细胞的优选方法是使用等渗10％海藻糖溶液冻干。
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