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公开(公告)号：US6096036A
公开(公告)日：2000-08-01
申请号：US72962
申请日：1998-05-05
CPC分类号： B82Y15/00 , A61M25/0041 , A61B2017/00053 , A61B2017/00057 , A61B2017/00243 , A61B2017/00867 , A61M2025/0161 , A61M25/0147 , A61M25/0152 , A61N1/056
摘要： A catheter has a stylet formed of a shape-retentive and resilient material having a preformed curved shape at its distal end resulting in the catheter sheath having the preformed curved shape. The catheter sheath has a plurality of electrodes at its distal end for contacting selected biological tissue for imparting ablation energy thereto. The catheter sheath also has an axially mounted tendon for causing deflection of the distal end. The stylet material permits straightening the catheter sheath during insertion into the patient and advancing the electrodes to the target tissue. Upon removal of the straightening forces, such as by entry into a chamber of the heart, the stylet material resumes its preformed curved distal shape thereby forcing the catheter distal end with the electrodes into the same preformed curved shape. The operator may place the curved distal end into contact with the target tissue and axially move the tendon as desired to gain greater control over the bend in the distal end of the catheter sheath to adjust the radius of curvature of the distal end to obtain greater contact of the electrodes with the heart tissue. Preferably, the stylet is formed of nitinol.
摘要翻译： 导管具有由形状保持性和弹性材料形成的探针，其在其远端处具有预成型的弯曲形状，导致导管护套具有预成型的弯曲形状。 导管鞘在其远端具有多个电极，用于接触选定的生物组织以向其施加消融能量。 导管护套还具有轴向安装的腱，用于引起远端的偏转。 探针材料允许在插入患者期间矫正导管鞘，并将电极推进到靶组织。 在去除矫直力时，例如通过进入心脏室，探针材料恢复其预先形成的弯曲远端形状，从而迫使导管远端与电极形成相同的预成形弯曲形状。 操作者可以将弯曲的远端放置成与目标组织接触，并根据需要轴向移动肌腱以获得对导管套管远端的弯曲部的更大控制，以调节远端的曲率半径以获得更大的接触 的电极与心脏组织。 探针最好由镍钛诺形成。
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2.发明授权公开(公告)号：US06869414B2
公开(公告)日：2005-03-22
申请号：US10105087
申请日：2002-03-22
CPC分类号： A61M25/0147 , A61M25/0041 , A61M25/0138 , A61M25/0152 , A61M2025/0161 , A61M2025/0163
摘要： A catheter employs a pre-formed distal end and a proximal deflection mechanism for steering the catheter. A shaped member extends from a shaped region of the catheter sheath to at least a portion of an anchor region. A steering ribbon extends from a proximal region of the sheath and passes within at least a portion of the anchor region. A distal end of the steering ribbon is joined with a proximal portion of the shaped member. At least one steering tendon is disposed within the sheath and has a first end attached at the anchor region and a second end located at the proximal region of the sheath. Movement of the steering tendon in a proximal direction causes the deflection region to deflect relative to the longitudinal axis of the catheter while the shape of shaped region of the sheath is substantially maintained.
摘要翻译： 导管采用预先形成的远端和用于转导导管的近端偏转机构。 成形构件从导管护套的成形区域延伸到锚定区域的至少一部分。 转向带从护套的近侧区域延伸并且在锚定区域的至少一部分内通过。 转向带的远端与成形构件的近端部分连接。 至少一个转向筋设置在护套内并且具有附接在锚定区域处的第一端和位于护套的近侧区域处的第二端。 转向腱在近端方向的移动导致偏转区域相对于导管的纵向轴线偏转，同时护套的成形区域的形状基本上保持。
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公开(公告)号：US06648875B2
公开(公告)日：2003-11-18
申请号：US09849325
申请日：2001-05-04
IPC分类号： A61M25098
CPC分类号： A61M25/0136
摘要： A catheter handle includes a steering controller to be used in conjunction with a steerable catheter shaft, and a steering tendon tensioning device. The operator deflects the profile of a distal-end region of the catheter by rotating the steering controller. Spring devices located on the steering tendons maintain the steering tendons in tension during manipulation of the steering controller. A locking device locks the steering controller in place relative to the handle.
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公开(公告)号：US06270496B1
公开(公告)日：2001-08-07
申请号：US09516280
申请日：2000-03-01
IPC分类号： A61B1818
CPC分类号： B82Y15/00 , A61B2017/00053 , A61B2017/00057 , A61B2017/00243 , A61B2017/00867 , A61M25/0041 , A61M25/0147 , A61M25/0152 , A61M2025/0161 , A61N1/056
摘要： A catheter has a stylet formed of a shape-retentive and resilient material having a preformed curved shape at its distal end resulting in the catheter sheath having the preformed curved shape. The catheter sheath has a plurality of electrodes at its distal end for contacting selected biological tissue for imparting ablation energy thereto. The catheter sheath also has an axially mounted tendon for causing deflection of the distal end. The stylet material permits straightening the catheter sheath during insertion into the patient and advancing the electrodes to the target tissue. Upon removal of the straightening forces, such as by entry into a chamber of the heart, the stylet material resumes its preformed curved distal shape thereby forcing the catheter distal end with the electrodes into the same preformed curved shape. The operator may place the curved distal end into contact with the target tissue and axially move the tendon as desired to gain greater control over the bend in the distal end of the catheter sheath to adjust the radius of curvature of the distal end to obtain greater contact of the electrodes with the heart tissue. Preferably, the stylet is formed of nitinol.
摘要翻译： 导管具有由形状保持性和弹性材料形成的探针，其在其远端处具有预成型的弯曲形状，导致导管护套具有预成型的弯曲形状。 导管鞘在其远端具有多个电极，用于接触选定的生物组织以向其施加消融能量。 导管护套还具有轴向安装的腱，用于引起远端的偏转。 探针材料允许在插入患者期间矫正导管鞘，并将电极推进到靶组织。 在去除矫直力时，例如通过进入心脏室，探针材料恢复其预先形成的弯曲远端形状，从而迫使导管远端与电极形成相同的预成形弯曲形状。 操作者可以将弯曲的远端放置成与目标组织接触，并根据需要轴向移动肌腱以获得对导管套管远端的弯曲部的更大控制，以调节远端的曲率半径以获得更大的接触 的电极与心脏组织。 探针最好由镍钛诺形成。
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公开(公告)号：US6146381A
公开(公告)日：2000-11-14
申请号：US73395
申请日：1998-05-05
CPC分类号： A61M25/0041 , A61B2017/00053 , A61B2017/00243 , A61B2017/00867 , A61M25/0147 , A61M25/0152 , A61N1/056
摘要： A catheter having a preformed distal shape for positioning a plurality of electrodes at a selected biological site includes a sheath having a preformed bend in the distal end region to distribute axial forces applied, in the distal direction, to the distal end region over a surface area of the distal end region proximal the distal tip. Also included in the catheter sheath is a stylet formed of a material capable of retaining a shape with the distal end of the stylet shaped in the preformed bend. Preferably, the preformed bend is approximately 45 degrees. Axial forces applied to the catheter are deflected to cause bowing of the catheter so that a larger surface area of the catheter contacts the tissue, rather than the smaller surface area of the distal tip. In other aspects, the portion of the sheath coincident with the preformed bend has a lower durometer, the stylet is more flexible by having a reduced diameter and the electrodes are located proximal to the preformed bend.
摘要翻译： 具有用于在选定的生物部位定位多个电极的预形成的远端形状的导管包括在远端区域中具有预成型弯曲的护套，用于将远端方向上施加的轴向力分布在表面区域上的远端区域 的远端区域。 还包括在导管鞘中的探针是由能够保持形状的材料形成的探针，所述探针的形状与预成形弯曲部中形状的探针的远端相连。 优选地，预成形弯曲部约为45度。 施加到导管的轴向力被偏转以引起导管弯曲，使得导管的较大表面积接触组织，而不是远端尖端的较小表面积。 在其他方面，护套与预成形弯曲部重合的部分具有较低的硬度，通过具有减小的直径并且电极位于预先形成的弯曲部的近侧，探针更灵活。
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6.发明授权公开(公告)号：US07419477B2
公开(公告)日：2008-09-02
申请号：US10855544
申请日：2004-05-27
CPC分类号： A61M25/0147 , A61M25/0041 , A61M25/0138 , A61M25/0152 , A61M2025/0161 , A61M2025/0163
摘要： Methods of using a catheter involve providing a sheath comprising a proximal region, a deflection region, a distal-end region including a shapeable region, an anchor region defined between the deflection region and the shapeable region, and a longitudinal axis. The method also involves imparting a pre-established shape to the shapeable region. The method further involves applying axial force in a proximal direction at the anchor region so as to cause the deflection region to deflect relative to the longitudinal axis while the pre-established shape imparted to the shapeable region of the sheath is substantially maintained.
摘要翻译： 使用导管的方法包括提供包括近端区域，偏转区域，包括可形成区域的远端区域，限定在偏转区域和可成形区域之间的锚定区域以及纵向轴线的护套。 该方法还涉及将可建立的形状赋予可塑区域。 该方法还包括在锚定区域处沿近端方向施加轴向力，以使得偏转区域相对于纵向轴线偏转，同时基本上保持赋予护套的可塑区域的预先确定的形状。
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公开(公告)号：US06605086B2
公开(公告)日：2003-08-12
申请号：US09848114
申请日：2001-05-02
IPC分类号： A61B1818
CPC分类号： A61M25/0144 , A61M25/0147 , A61M2025/015
摘要： A catheter includes a steering mechanism for manipulating the distal end of the catheter to obtain a plurality of deflection profiles, and a torque transfer system at the distal portion to enhance torque transfer from the handle to the distal tip. The steering mechanism includes two steering tendons. The steering tendons are attached to the distal-end region of the catheter. The steering tendons may be located approximately angularly aligned, thus causing the deflection profiles to be unidirectional. Alternatively, the steering tendons may be located angularly separated from each other, thus causing the deflection profiles to be bidirectional. In other aspects, the torque transfer system includes a flat ribbon within the relatively flexible distal-end region to enhance torque transfer through the distal-end region of the catheter.
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公开(公告)号：US06585718B2
公开(公告)日：2003-07-01
申请号：US09848087
申请日：2001-05-02
IPC分类号： A61B100
CPC分类号： A61M25/0138 , A61B18/1492 , A61B2017/003 , A61B2018/00577 , A61M25/0141 , A61M25/0144 , A61M25/0147 , A61M2025/015
摘要： A catheter includes a steering mechanism for manipulating the distal end of the catheter to obtain a plurality of deflection profiles, a torque transfer system to enhance torque transfer from the handle to the distal tip, and a support system to reduce undesirable deformation of the distal-end region during steering. The torque transfer system includes a flat ribbon within the relatively flexible distal-end region to enhance torque transfer through the distal-end region of the catheter. The support system includes a compression cage and longitudinal struts that are located within the distal-end region of the catheter. The support system can support axial loads and deflect laterally in the direction of the steering, thereby reducing the amount of stretching and compression of the catheter sheath within the deflecting region.
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9.发明申请RADIOPAQUE INTRALUMINAL STENTS COMPRISING COBALT-BASED ALLOYS CONTAINING ONE OR MORE PLATINUM GROUP METALS, REFRACTORY METALS, OR COMBINATIONS THEREOF 有权包含含有一种或多种铂族金属，碱金属或其组合的基于钴的合金的放射性体系公开(公告)号：US20130204353A1
公开(公告)日：2013-08-08
申请号：US13830404
申请日：2013-03-14
申请人： Pamela A. Kramer-Brown , Kayla L. Calvert , John A. Simpson , Stephen D. Pacetti , Austin M. Leach
发明人： Pamela A. Kramer-Brown , Kayla L. Calvert , John A. Simpson , Stephen D. Pacetti , Austin M. Leach
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/06 , A61F2250/0098 , A61L31/022 , A61L31/18 , C22C1/0433 , C22C19/05 , C22C19/07 , C22C27/00 , C22C27/04 , C22C27/06
摘要： Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, precious metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Refractory metals include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, and precious metals include silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute at least partially for nickel, such that the alloy exhibits reduced nickel content, or is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.
摘要翻译： 实施例涉及由包含钴，铬和一种或多种铂族金属，难熔金属，贵金属或其组合的钴基合金形成的不透射线的可植入结构（例如，支架）。 铂族金属包括铂，钯，钌，铑，锇和铱。 耐火金属包括锆，铌，铑，钼，铪，钽，钨，铼，贵金属包括银和金。 在一个实施方案中，所述一种或多种包括的铂族或难熔金属至少部分地代替镍，使得该合金显示出降低的镍含量或基本上不含镍。 与包括更大量的镍的类似合金相比，支架表现出改善的射线不透性。
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公开(公告)号：US08403885B2
公开(公告)日：2013-03-26
申请号：US11958106
申请日：2007-12-17
申请人： Ramon Arana , Daniel Brown , Curt A. Novak , Justin K. Mann , John A. Simpson , Bruce M. Wilson , Leonard D. Barbod
发明人： Ramon Arana , Daniel Brown , Curt A. Novak , Justin K. Mann , John A. Simpson , Bruce M. Wilson , Leonard D. Barbod
IPC分类号： A61M25/10
CPC分类号： A61M25/1027 , A61M25/0054 , A61M25/0069 , A61M25/1006 , A61M25/1034 , A61M25/104 , A61M2025/1061 , A61M2025/1093 , A61M2205/32 , B29C65/48 , B29C66/10 , B29L2031/7543
摘要： A catheter having shaft segments which are joined together by a strong bond providing a low profile shaft section with a flexibility transition and/or a compositional transition. A balloon catheter embodying features of the invention has a distal tip member and a coupling band member surrounding a junction of an inner tubular member of the shaft, and has a gradual change in bending stiffness along a distal end section of the shaft which extends distally from a location within the balloon interior. Another catheter embodying features of the invention has shaft segments joined together by a diagonal seam.
摘要翻译： 一种具有轴段的导管，其通过强结合连接在一起，提供具有柔性转变和/或组成转变的低轮廓轴部分。 体现本发明特征的气囊导管具有远侧末端构件和围绕轴的内部管状构件的接合处的联接带构件，并且沿着轴的远端部分沿着远端延伸的弯曲刚度逐渐变化 气球内部的一个位置。 体现本发明特征的另一导管具有通过对角接缝连接在一起的轴段。
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