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公开(公告)号：US5534018A
公开(公告)日：1996-07-09
申请号：US346661
申请日：1994-11-30
申请人： John D. Wahlstrand , Daniel J. Baxter , R. Michael Ecker , Daniel R. Greeninger , Charles G. Yerich
发明人： John D. Wahlstrand , Daniel J. Baxter , R. Michael Ecker , Daniel R. Greeninger , Charles G. Yerich
CPC分类号： A61N1/3706 , A61N2001/083
摘要： A method and apparatus for determining the availability of unipolar and/or bipolar pacing/sensing paths in a body-implantable cardiac pacing system. In one embodiment, a pacemaker system includes impedance monitoring circuitry for periodically measuring impedance between pairs of electrodes that are potentially available for pacing and/or sensing. This impedance monitoring circuitry includes circuitry for delivering excitation pulses between pairs of potentially available electrodes (including the pacemaker canister in the case of unipolar pacing or sensing), and for monitoring the current and voltage between those pairs of electrodes during delivery of an excitation pulse. Availability of a pair of electrodes for pacing and/or sensing is indicated if the impedance between a pair of electrodes is found to lie within a predetermined range. Detection of availability of a particular pair of electrodes is used initially as an indication that the pacing system has been implanted, and is also used to distinguish between unipolar and bipolar leads in the pacing system.
摘要翻译： 一种用于确定体内植入式心脏起搏系统中单极和/或双极起搏/感测路径的可用性的方法和装置。 在一个实施例中，起搏器系统包括用于周期性地测量潜在可用于起搏和/或感测的电极对之间的阻抗的阻抗监测电路。 该阻抗监测电路包括用于在潜在可用电极对（包括单极起搏或感测的情况下包括起搏器罐）之间传递激励脉冲的电路，以及用于在激励脉冲传送期间监测这些电极对之间的电流和电压。 如果发现一对电极之间的阻抗位于预定范围内，则指示用于起搏和/或感测的一对电极的可用性。 最初使用特定对电极的可用性的检测作为起搏系统已植入的指示，并且还用于区分起搏系统中的单极和双极引线。
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公开(公告)号：US5271395A
公开(公告)日：1993-12-21
申请号：US870062
申请日：1992-04-17
CPC分类号： A61N1/36585
摘要： A rate-responsive cardiac pacemaker comprising a minute ventilation circuit and an activity circuit. The minute ventilation circuit computes a first target pacing rate as a function of measurements of the patient's pleural blood impedance, and the activity circuit computes a second target pacing rate as a function of measured levels of patient activity. A rate control function establishes a rate-responsive pacing rate based on the first and second target pacing rates. The minute ventilation circuit delta-modulates an analog impedance waveform and maintains short-term and long-term weighted averages of delta-modulator output counts. Variations in the difference between the short-term and long-term weighted average values are determinative of the first target pacing rate. Variations in an activity sensor output signal are determinative of the second target pacing rate. Physician-programmable parameters for the pacemaker include selection of a rate-response setting, upper and lower pacing rate limits, and rate-smoothing attack and decay settings.
摘要翻译： 一种速率响应心脏起搏器，包括微通风回路和活动电路。 分钟通气电路根据患者胸膜血阻抗的测量值来计算第一目标起搏速率，并且活动电路根据测量的患者活动水平计算第二目标起搏速率。 速率控制功能基于第一和第二目标起搏速率建立速率响应起搏速率。 分钟通风电路对模拟阻抗波形进行delta调制，并维持Δ调制器输出计数的短期和长期加权平均值。 短期和长期加权平均值差异的变化是第一个目标起搏率的决定因素。 活动传感器输出信号的变化是第二目标起搏速率的决定因素。 心脏起搏器的医师可编程参数包括选择速率响应设置，上限和下限起搏速率限制以及速率平滑攻击和衰减设置。
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公开(公告)号：US20080183225A1
公开(公告)日：2008-07-31
申请号：US11669378
申请日：2007-01-31
申请人： Thomas H. Adamski , Daniel R. Greeninger , John C. Mertz , Christopher C. Stancer , James Strom
发明人： Thomas H. Adamski , Daniel R. Greeninger , John C. Mertz , Christopher C. Stancer , James Strom
IPC分类号： A61N1/05
CPC分类号： A61N1/375 , A61B5/0422 , A61B2560/0468 , A61N1/0504 , A61N1/3702 , A61N1/3756
摘要： Apparatus and method according to the disclosure relate to a mechanically and electrically coupling a plurality of electrodes to major opposing surface portions of an implantable medical device (IMD). The surface portions can comprise major opposing surfaces of a connector module of the IMD and/or substantially planar metallic surfaces of the IMD. The electrodes provide a subcutaneous cardiac activity sensing device via the plurality of electrodes which can be used in conjunction with one or more electrodes disposed in an insulative shroud coupled to the peripheral, minor surfaces of the IMD.
摘要翻译： 根据本公开的装置和方法涉及将多个电极机械地和电耦合到可植入医疗装置（IMD）的主要相对表面部分。 表面部分可以包括IMD的连接器模块的主要相对表面和/或IMD的基本平坦的金属表面。 电极通过多个电极提供皮下心脏活动感测装置，其可以与设置在耦合到IMD的周边的次表面的绝缘罩中的一个或多个电极结合使用。
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4.发明授权公开(公告)号：US06804552B2
公开(公告)日：2004-10-12
申请号：US10004025
申请日：2001-10-31
IPC分类号： A61N100
CPC分类号： A61N1/37 , A61N1/368 , A61N1/3718 , A61N1/3912 , A61N1/3956
摘要： An improved switching system for use with an implantable medical device (IMD) is described. The system utilizes Micro-Electrical-Mechanical system (MEMs) switches in place of one or more switches formerly implemented using transistor networks. Any type of switching circuit used within an IMD may be implemented using this technology. For example, MEMs switches may be utilized in a circuit for selectably delivering electrical stimulation to a patient, and/or in a circuit for providing surge protection. The fabrication of the MEMs switches may be performed using one or more separate tubs or wells on a silicon substrate to isolate switching circuitry from other IMD circuitry.
摘要翻译： 描述了一种用于可植入医疗装置（IMD）的改进的切换系统。 该系统采用微机电系统（MEM）开关代替先前使用晶体管网络实现的一个或多个开关。 可以使用该技术来实现在IMD内使用的任何类型的开关电路。 例如，可以在电路中使用MEM开关，以可选择地向患者输送电刺激，和/或在用于提供浪涌保护的电路中。 可以使用硅衬底上的一个或多个单独的桶或阱来执行MEM开关的制造，以将开关电路与其他IMD电路隔离开来。
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公开(公告)号：US06438422B1
公开(公告)日：2002-08-20
申请号：US09467288
申请日：1999-12-20
IPC分类号： A61N1362
CPC分类号： G06F1/324 , A61N1/025 , A61N1/3605 , A61N1/362 , A61N1/378 , G06F1/3203 , G06F1/3296 , H03K19/0019 , Y02D10/126 , Y02D10/172
摘要： A system for minimizing power dissipation within an implantable medical device through use of adiabatic logic is disclosed. The system includes a first and a second sub-circuit of the implantable medical device. An electrical connection interconnects the first and the second sub-circuits, the electrical connection including a capacitive element. Circuitry, which charges the capacitive element of the electrical connection to generate a ramp logic signal, is connected to the capacitive element. The ramp logic signal includes a frequency of less than 500 kilohertz, thereby creating a low frequency, low power system which reduces energy dissipation to the surrounding environment.
摘要翻译： 公开了一种通过使用绝热逻辑来最小化可植入医疗装置内的功率耗散的系统。 该系统包括可植入医疗装置的第一和第二子电路。 电连接将第一和第二子电路互连，电连接包括电容元件。 将电连接的电容元件充电以产生斜坡逻辑信号的电路连接到电容元件。 斜坡逻辑信号包括小于500千赫的频率，从而产生低频，低功率系统，从而减少对周围环境的能量耗散。
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6.发明授权Interrogation of an implantable medical device using broadcast audible sound communication 失效使用广播声音通信的可植入医疗设备的询问公开(公告)号：US06370433B1
公开(公告)日：2002-04-09
申请号：US09491205
申请日：2000-01-25
IPC分类号： A61N136
CPC分类号： A61N1/3727 , A61N1/37217 , A61N1/37223
摘要： Methods and apparatus for communication of implantable medical device (IMD) information, including interrogation of programmed parameter values, operating modes and conditions of operation, confirmation of programmed changes thereof, interrogation of data stored in the IMD, and patient warnings or other messages by RF transmission of audible sounds generated by the IMD are disclosed. The IMD includes an RF transmitter that broadcasts or transmits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The broadcast radio signal is received, and the audible sounds are demodulated and reproduced by a radio receiver as voiced statements or musical is tones that convey human understandable messages comprising IMD information generated during programming and interrogation sessions and warnings or status messages to the patient at other times.
摘要翻译： 用于通信植入式医疗装置（IMD）信息的方法和装置，包括询问编程的参数值，操作模式和操作条件，确定其编程的变化，询问存储在IMD中的数据，以及通过RF的患者警告或其他消息 公开了由IMD产生的可听见的声音的传输。 IMD包括RF发射器，其广播或发送与编程或询问操作算法相关的模拟存储器中存储的有声语音或音调的声音或发音，或警告触发事件。 广播无线电信号被接收，并且可听见的声音被无线电接收机解调和再现，因为语音或音乐是将编程和询问会话期间生成的包含IMD信息的人可理解的消息和警告或状态消息传递给患者的音调 次
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7.发明授权Broadcast audible sound communication of programming change in an implantable medical device 失效广播可植入式医疗设备中的编程改变的声音通信公开(公告)号：US06216038B1
公开(公告)日：2001-04-10
申请号：US09491395
申请日：2000-01-25
IPC分类号： A61N136
CPC分类号： A61N1/3727 , A61N1/37217 , A61N1/37223 , A61N1/37258 , Y10S128/903
摘要： Methods and apparatus for communication of implantable medical device (IMD) information, including interrogation of programmed parameter values, operating modes and conditions of operation, confirmation of programmed changes thereof, interrogation of data stored in the IMD, and patient warnings or other messages by RF transmission of audible sounds generated by the IMD are disclosed. The IMD includes an RF transmitter that broadcasts or transmits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The broadcast radio signal is received, and the audible sounds are demodulated and reproduced by a radio receiver as voiced statements or musical tones that convey human understandable messages comprising IMD information generated during programming and interrogation sessions and warnings or status messages to the patient at other.
摘要翻译： 用于通信植入式医疗装置（IMD）信息的方法和装置，包括询问编程的参数值，操作模式和操作条件，确定其编程的变化，询问存储在IMD中的数据，以及通过RF的患者警告或其他消息 公开了由IMD产生的可听见的声音的传输。 IMD包括RF发射器，其广播或发送与编程或询问操作算法相关的模拟存储器中存储的有声语音或音调的声音或发音，或警告触发事件。 广播无线电信号被接收，并且声音由无线电接收机解调和再现，作为语音或乐音，其将可编程和询问会话期间生成的包含IMD信息的人可理解的消息和警告或状态消息传达给患者。
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公开(公告)号：US6082367A
公开(公告)日：2000-07-04
申请号：US69559
申请日：1998-04-29
CPC分类号： A61N1/37258
摘要： Methods and apparatus for communication of implantable medical device (IMD) information, including confirmation of programming and programmed parameter values, operating modes and programmed changes thereof and data stored in the IMD, by emission of audible sounds by the IMD are disclosed. The IMD includes an audio transducer that emits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The audible sounds can comprise the sole uplink transmission or may augment the contemporaneous uplink RF transmission of stored data, and/or programmed operating modes and parameters and/or device operations and states in an interrogation or during programming. To conserve energy, the audible sounds accompanying interrogation and programming of the IMD are at a low volume that preferably cannot be heard without use of an external audio amplifier or stethoscope. Voiced statements warning of battery energy depletion or imminent delivery of a therapy are emitted at a higher volume that is sufficient to be heard by the patient, so that the patient can take appropriate action. The volume of audible sounds confirming programmed changes made by a patient using a limited function programmer or magnet is also increased so that the patient can hear them.
摘要翻译： 公开了通过IMD发出可听见的声音来传送植入式医疗装置（IMD）信息的方法和装置，包括编程和编程参数值的确认，操作模式及编程改变以及存储在IMD中的数据。 IMD包括音频换能器，其发射可听声音，包括存储在与编程或询问操作算法相关的模拟存储器中的语音或音调，或者到警告触发事件。 可听见的声音可以包括唯一的上行链路传输，或者可以在询问中或在编程期间增加存储数据的同时期上行链路RF传输和/或编程的操作模式和参数和/或设备操作和状态。 为了节省能量，伴随着IMD的询问和编程的可听见的声音处于较低的音量，最好在不使用外部音频放大器或听诊器的情况下听不到声音。 电池能量消耗或治疗即将发送的声明声明以足以由患者听到的较高音量发出，以便患者能够采取适当的动作。 使用有限功能的编程器或磁铁确认病人进行的编程改变的可听见声音的音量也增加，以便患者可以听到它们的声音。
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9.发明申请TISSUE INGROWTH ENHANCEMENT FOR SHROUD-BASED PLATE ELECTRODES CONFIGURED FOR CHRONIC IMPLANTATION 审中-公开用于慢性植入配置的基于硅酸盐的电极组织的组织生长增强公开(公告)号：US20080183089A1
公开(公告)日：2008-07-31
申请号：US11669442
申请日：2007-01-31
IPC分类号： A61B5/042
CPC分类号： A61B5/042 , A61B2562/02 , A61N1/05 , A61N1/08
摘要： Apparatus and method according to the disclosure relate to substantially planar cardiac-sensing electrodes and a shroud member utilizing protruding surface features such as one or more discrete and/or elongated projections, bumps, bosses and the like. For example, the exposed exterior surface of an electrode includes one or more protruding features that promote flow of body fluids therearound and potentially reduce tissue encapsulation.
摘要翻译： 根据本公开的装置和方法涉及基本上平面的心脏感测电极和利用突出表面特征（例如一个或多个离散和/或伸长的突起，凸起，凸起等）的护罩构件。 例如，电极的暴露的外表面包括一个或多个突出特征，其促使周围的体液流动并潜在地减少组织包封。
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10.发明授权Feedthrough assembly for implantable medical devices and methods for providing same 有权用于可植入医疗器械的馈通组件及其提供方法
公开(公告)号：US6052623A
公开(公告)日：2000-04-18
申请号：US201059
申请日：1998-11-30
IPC分类号： A61N1/375
CPC分类号： A61N1/3754
摘要： A feedthrough assembly for an implantable medical device includes one or more electrically conductive pins extending through apertures in a case of the medical device with the electrically conductive pins being insulated from the case. The feedthrough assembly further includes a printed circuit board having a diode protection circuit mounted thereon. The printed circuit board forms at least a part of electrically conductive paths for connection of the electrically conductive pins to a medical device circuit assembly mounted within the case. The printed circuit board further provides for electrical connection of the diode protection circuit mounted thereon between the electrically conductive pins and the case.
摘要翻译： 用于可植入医疗装置的馈通组件包括在医疗装置的壳体中延伸穿过孔的一个或多个导电销，其中导电销与壳体绝缘。 馈通组件还包括其上安装有二极管保护电路的印刷电路板。 印刷电路板形成用于将导电针连接到安装在壳体内的医疗装置电路组件的导电路径的至少一部分。 印刷电路板还提供安装在其上的二极管保护电路在导电引脚和外壳之间的电连接。
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