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公开(公告)号：US07925445B2
公开(公告)日：2011-04-12
申请号：US11004390
申请日：2004-12-03
申请人： John Francis Petrilla , Patrick T. Petruno , Daniel B. Roitman , Rong Zhou , Michael John Brosnan
发明人： John Francis Petrilla , Patrick T. Petruno , Daniel B. Roitman , Rong Zhou , Michael John Brosnan
IPC分类号： G01N33/48 , G01N33/543 , C12Q1/00 , A61B5/00
CPC分类号： G01N35/00732
摘要： A read-write assay system includes providing an assay device; and writing assay device information to the assay device for subsequent reading of the assay device information from the assay device; or performing an assay with the assay device and subsequent writing of the assay related information to the assay device or reading of assay related information from the assay device.
摘要翻译： 读写测定系统包括提供测定装置; 以及将测定装置信息写入测定装置，以便随后从测定装置读取测定装置信息; 或使用测定装置进行测定，然后将测定相关信息写入测定装置或从测定装置读取测定相关信息。
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公开(公告)号：US10041941B2
公开(公告)日：2018-08-07
申请号：US12410178
申请日：2009-03-24
IPC分类号： G01N33/558 , G01N33/58 , G01N21/77 , G01N35/00
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.
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公开(公告)号：US20090180928A1
公开(公告)日：2009-07-16
申请号：US12410178
申请日：2009-03-24
CPC分类号： G01N33/558 , G01N33/582 , G01N2021/7786 , G01N2035/00108
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.
摘要翻译： 在一个方面，分析测试条包括特异性结合目标分析物的测试标签和对目标分析物没有任何特异性结合亲和力并且具有与测试标记不同的光学特性的对照标记。 在另一方面，测定试片包括特异性结合目标分析物和至少一种对目标分析物没有任何特异性结合亲和力的非特异性结合标记的测试标记。 还描述了读取测定条带的系统和方法。
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公开(公告)号：US20090214383A1
公开(公告)日：2009-08-27
申请号：US12410167
申请日：2009-03-24
IPC分类号： G01N31/22
CPC分类号： G01N33/558 , G01N33/582 , G01N2021/7786 , G01N2035/00108
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.
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公开(公告)号：US20090180927A1
公开(公告)日：2009-07-16
申请号：US12409877
申请日：2009-03-24
申请人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
发明人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
IPC分类号： G01N31/22
CPC分类号： G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要： An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
摘要翻译： 测定试片包括流路，样品接收区，标签，包括感兴趣区域的检测区和至少一个位置标记。 所述至少一个位置标记相对于所述感兴趣区域对齐，使得所述至少一个位置标记的位置指示所述感兴趣区域的位置。 诊断测试系统包括从测试条的暴露区域获得光强度测量的读取器，以及数据分析器，其执行以下至少一个：（a）基于至少一个（a）识别从测试区域获得的光强度测量中的一个 测量从所述至少一个参考特征获得的，以及（b）基于从所述至少一个参考特征获得的至少一个测量值生成修改所述读取器的至少一个操作参数的控制信号。
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公开(公告)号：US10753931B2
公开(公告)日：2020-08-25
申请号：US12410182
申请日：2009-03-24
IPC分类号： G01N33/558 , G01N33/58 , G01N21/77 , G01N35/00
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.
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公开(公告)号：US09891217B2
公开(公告)日：2018-02-13
申请号：US12410167
申请日：2009-03-24
IPC分类号： G01N33/558 , G01N33/58 , G01N21/77 , G01N35/00
CPC分类号： G01N33/558 , G01N33/582 , G01N2021/7786 , G01N2035/00108
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.
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公开(公告)号：US09091631B2
公开(公告)日：2015-07-28
申请号：US13360081
申请日：2012-01-27
IPC分类号： G01N21/17 , G01N21/84 , G01N33/558
CPC分类号： G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要： In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements.
摘要翻译： 一方面，诊断测试系统包括壳体，读取器和数据分析器。 壳体包括用于接收测试条的端口。 读取器从暴露于光学检查的检测区域的区域的局部区域获得可分离的光强度测量值，其中每个局部区域的特征在于至少一个小于第一维度的表面尺寸。 数据分析器识别从至少一个测试区域获得的光强度测量结果中的一个，并从所识别的光强测量中计算至少一个参数。 在另一方面，读取器从检测区域的暴露表面区域的多个对应区域中的每一个获得相应的一组光强度测量值，并且数据分析器从至少一个光强度测量集合中计算至少一个参数 。
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公开(公告)号：US20120129272A1
公开(公告)日：2012-05-24
申请号：US13360081
申请日：2012-01-27
IPC分类号： G01N33/543
CPC分类号： G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要： In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements.
摘要翻译： 一方面，诊断测试系统包括壳体，读取器和数据分析器。 壳体包括用于接收测试条的端口。 读取器从暴露于光学检查的检测区域的区域的局部区域获得可分离的光强度测量值，其中每个局部区域的特征在于至少一个小于第一维度的表面尺寸。 数据分析器识别从至少一个测试区域获得的光强度测量结果中的一个，并从所识别的光强测量中计算至少一个参数。 在另一方面，读取器从检测区域的暴露表面区域的多个对应区域中的每一个获得相应的一组光强度测量值，并且数据分析器从至少一个光强度测量集合中计算至少一个参数 。
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公开(公告)号：US20090180925A1
公开(公告)日：2009-07-16
申请号：US12409861
申请日：2009-03-24
申请人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
发明人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
IPC分类号： G01N31/22
CPC分类号： G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要： An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
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