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11 条记录 (耗时 0.016 秒)

    Lithium ion-selective membrane electrode
    1.
    发明授权
    Lithium ion-selective membrane electrode 失效
    锂离子选择性膜电极

    公开(公告)号：US4770759A

    公开(公告)日：1988-09-13

    申请号：US883108

    申请日：1986-07-08

    申请人： Chung C. Young ,  John Hiti

    发明人： Chung C. Young ,  John Hiti

    IPC分类号： G01N27/333 ,  G01N27/46

    CPC分类号： G01N27/3335

    摘要： An electrode for determining the lithium content of a liquid sample to be tested, has a membrane containing a lithium ion selective compound and a plasticizer, the improvement wherein the plasticizer is a liquid, lipophilic dialkyl phthalate compound or a liquid phenyl phenyl ether compound that has a strong electron withdrawing group at an ortho position on one of the phenyl rings. The ion selective compound has the formula: ##STR1## wherein A is an alkyl group having between 8 and 16 carbon atoms, B is an alkyl group having between 1 and 4 carbon atoms, and each C and D is, independently, a hydrogen atom or an alkyl group having between 1 and 16 carbon atoms, provided that both C and D are not alkyl groups having greater than 4 carbon atoms.

    摘要翻译： 用于测定待测试液体样品的锂含量的电极具有含有锂离子选择性化合物和增塑剂的膜，改进之处在于，增塑剂是液体，亲油性邻苯二甲酸二烷基酯化合物或液体苯基苯基醚化合物，其具有 在一个苯环上的邻位的强吸电子基团。 离子选择性化合物具有下式：其中A是具有8至16个碳原子的烷基，B是具有1至4个碳原子的烷基，并且每个C和D独立地是氢原子 或具有1至16个碳原子的烷基，条件是C和D都不是具有大于4个碳原子的烷基。

    Magnesium electrode
    2.
    发明授权
    Magnesium electrode 失效
    镁电极

    公开(公告)号：US5350518A

    公开(公告)日：1994-09-27

    申请号：US105340

    申请日：1993-08-11

    申请人： John Hiti ,  Chung C. Young

    发明人： John Hiti ,  Chung C. Young

    IPC分类号： G01N27/333 ,  B01D71/06

    CPC分类号： G01N27/3335

    摘要： The magnesium ion content of a sample is determined by contacting the sample with a magnesium ion selective membrane including a 1,10-phenanthroline having an H group at positions 2 and 9. Examples of preferred 1,10-phenanthrolines include 4,7-diphenyl-1,10-phenanthroline, N-dodecyl-N-methyl-1,10-phenanthroline-4-carboxamide, 4-undecyl-1,10-phenanthroline, 4,7-diundecyl-1,10-phenanthroline and 5-nonyl-1,10-phenanthroline-4-carboxylate.

    摘要翻译： 样品的镁离子含量通过使样品与含有1和2的9位具有H基的1,10-菲咯啉的镁离子选择性膜接触来确定。优选的1,10-菲咯啉的实例包括4,7-二苯基 -1,10-菲咯啉，N-十二烷基-N-甲基-1,10-菲咯啉-4-甲酰胺，4-十一烷基-1,10-菲咯啉，4,7-二十一烷基-1,10-菲咯啉和5-壬基 -1,10-菲咯啉-4-羧酸酯。

    Apparatus and control kit for analyzing blood sample values including hematocrit
    5.
    发明授权
    Apparatus and control kit for analyzing blood sample values including hematocrit 失效
    用于分析血液样本值（包括血细胞比容）的仪器和控制组件

    公开(公告)号：US4686479A

    公开(公告)日：1987-08-11

    申请号：US757573

    申请日：1985-07-22

    申请人： Chung C. Young ,  Robert L. Coleman ,  Sheila M. Sullivan ,  John F. Grimes ,  Ferdnand Baumeister ,  Robert MacIndoe ,  Lou Catalano ,  Pat Coppola ,  Fred Spaziani ,  Guy Rodomista ,  James E. Fowler

    发明人： Chung C. Young ,  Robert L. Coleman ,  Sheila M. Sullivan ,  John F. Grimes ,  Ferdnand Baumeister ,  Robert MacIndoe ,  Lou Catalano ,  Pat Coppola ,  Fred Spaziani ,  Guy Rodomista ,  James E. Fowler

    IPC分类号： G01N27/06 ,  G01N33/483 ,  G01N33/487 ,  G01N33/49 ,  G01N27/02

    CPC分类号： G01N33/4915

    摘要： Hematocrit level of a blood sample is measured by flowing the sample along a liquid flow path and using electrodes in the flow path to obtain electrical signals representative of the sample's electrical conductivity and of the concentration of an ion species in the path, either before or after the sample measurement. Electrical signals are obtained for standardizing solution conductivity and ion species concentration. A tentative sample hematocrit value is derived from the sample and standardizing conductivity signals. Then the tentative hematocrit value is corrected with reference to the sample and standardizing ion concentration signals and to the known standardizing solution ion concentration value. A control solution of the ion species at known concentration is used for evaluating the hematocrit detection apparatus; the solution also includes an ion activity enhancing agent. A removable septum assembly is used in a blood sample component measuring apparatus in which at least two standardizing solutions are introduced into the flow path. The septum assembly comprises: (a) chamber-defining members, which define a plurality of chambers, the members being permanently attached to each other; and (b) flexible septa positioned between the chambers, each septum having a slit, the slits being aligned to sealably receive therethrough an elongated probe connected to a flush fluid and each remaining chamber being connected to a standardizing fluid introducing lines, the septum assembly being removably attached as a unit to the apparatus which includes means for releasably attaching the septum assembly in position to receive the probe through the slits.

    摘要翻译： 血液样品的血细胞比容水平通过沿着液体流动路径流动样品并使用流动路径中的电极来测量，以获得代表样品的电导率的电信号，以及在路径之前或之后的离子种类的浓度 样品测量。 获得电信号用于标准化溶液电导率和离子种类浓度。 从样品中导出临时样品血细胞比容值，并标准化电导率信号。 然后参照样品和标准化离子浓度信号以及已知的标准溶液离子浓度值校正临时血细胞比容值。 已知浓度的离子种类的对照溶液用于评价血细胞比容检测装置; 该溶液还包括离子活性增强剂。 在血液样品成分测量装置中使用可移除的隔膜组件，其中至少两个标准化溶液被引入到流动路径中。 隔膜组件包括：（a）室限定构件，其限定多个室，所述构件永久地彼此附接; 并且（b）位于所述室之间的柔性隔垫，每个隔膜具有狭缝，所述狭缝对准以可密封地容纳其中连接到冲洗流体的细长探针，并且每个剩余室连接到标准化流体引入管线，所述隔膜组件 可移除地附接到装置上，该装置包括用于将隔膜组件可释放地附接到适当位置以接收穿过狭缝的探针的装置。

    Method for measuring calcium
    7.
    发明授权
    Method for measuring calcium 失效
    钙测量方法

    公开(公告)号：US4724216A

    公开(公告)日：1988-02-09

    申请号：US796194

    申请日：1985-11-08

    申请人： Chung C. Young ,  Linda M. Mulholland

    发明人： Chung C. Young ,  Linda M. Mulholland

    IPC分类号： G01N33/84 ,  G01N33/20

    CPC分类号： G01N33/84 ,  Y10T436/107497 ,  Y10T436/25375

    摘要： A releasing reagent for releasing, as ionized calcium, protein-bound calcium in a biological sample for measurement of the ionized calcium, together with any ionized calcium originally present in the sample, using a calcium ion specific electrode, the releasing reagent including monochlorocoacetate salt, formate salt, and formic acid, in concentrations sufficient to render the pH of the sample, when mixed with the reagent, in the range of 4.0 to 5.5. Also disclosed is a method of measuring calcium in a liquid sample using such a releasing reagent.

    摘要翻译： 一种释放试剂，用于使用钙离子特异性电极释放生物样品中用于测量离子化钙的离子钙，蛋白质结合钙以及原样存在于样品中的任何离子钙，所述释放试剂包括一氯氯乙酸盐， 甲酸盐和甲酸，其浓度足以使样品的pH与试剂混合时在4.0至5.5的范围内。 还公开了使用这种释放试剂测量液体样品中的钙的方法。

    Potassium ion-selective membrane electrode
    8.
    发明授权
    Potassium ion-selective membrane electrode 失效
    钾离子选择性膜电极

    公开(公告)号：US4361473A

    公开(公告)日：1982-11-30

    申请号：US315919

    申请日：1981-10-28

    申请人： Chung C. Young ,  John P. Willis

    发明人： Chung C. Young ,  John P. Willis

    IPC分类号： C07D323/00 ,  G01N27/333 ,  G01N27/30

    CPC分类号： G01N27/3335

    摘要： In an electrode for determining the potassium ion content of a liquid sample to be tested, the electrode including a membrane having incorporated therein an ion selective component, the improvement in which the ion specific component is a compound of the formula: ##STR1## wherein each R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, and R.sub.8 is hydrogen or an alkyl group containing between one and about 20 carbon atoms, p is 0 or 1, n is one or more, and, each s and r, independently, is 1, 2, or 3, provided that, when p is 1, n is 8 or more.

    摘要翻译： 在用于测定待测试的液体样品的钾离子含量的电极中，所述电极包括其中并入有离子选择性组分的膜，其中离子特异性组分是下式化合物的改进：其中每个 R 1，R 2，R 3，R 4，R 5，R 6，R 7和R 8为氢或含有1至约20个碳原子的烷基，p为0或1，n为一个或多个， 独立地，为1,2或3，条件是当p为1时，n为8以上。

    Measurement of carbon dioxide in blood
    9.
    发明授权
    Measurement of carbon dioxide in blood 失效
    测量血液中的二氧化碳

    公开(公告)号：US5633169A

    公开(公告)日：1997-05-27

    申请号：US549028

    申请日：1995-10-27

    申请人： Chung C. Young ,  Jeffrey Chien

    发明人： Chung C. Young ,  Jeffrey Chien

    IPC分类号： G01N33/487 ,  G01N33/49 ,  G01N33/50

    CPC分类号： G01N33/4925 ,  Y10T436/25625

    摘要： A method of determining the total carbon dioxide concentration in plasma (TCO.sub.2 plasma) directly from a whole blood sample involves adjusting total carbon dioxide concentration measured in the whole blood sample (TCO.sub.2 whole blood) using a volume dilution factor (VDF) to give a value that is equivalent to TCO.sub.2 plasma.

    摘要翻译： 直接从全血样品中测定血浆中总二氧化碳浓度（TCO2血浆）的方法包括使用体积稀释因子（VDF）调整全血样品（TCO2全血）中测量的总二氧化碳浓度，以得到值 相当于TCO2等离子体。

    Apparatus for determining the concentration of water soluble species in biological fluid
    10.
    发明授权
    Apparatus for determining the concentration of water soluble species in biological fluid 失效
    用于测定生物液体中水溶性物质浓度的装置

    公开(公告)号：US5118473A

    公开(公告)日：1992-06-02

    申请号：US604124

    申请日：1990-10-26

    申请人： Robert L. Coleman ,  Chung C. Young

    发明人： Robert L. Coleman ,  Chung C. Young

    IPC分类号： G01N27/416 ,  G01N33/48 ,  G01N33/84

    CPC分类号： G01N33/84 ,  G01N33/48 ,  G01N33/492 ,  Y10S436/805 ,  Y10S436/806

    摘要： An apparatus for correcting an initial measurement of the concentration of a first water soluble species dissolved in a water-based component of a biological fluid that also includes a second water soluble species and a volume occupying component, the initial measurement having been taken using an original sample of the fluid that had been diluted by an amount of additional aqueous solution to form a diluted sample is disclosed; the concentration of the second water soluble species is measured in an undiluted sample of the biological fluid to obtain a direct concentration and is measured using a diluted sample of the fluid to obtain an indirect concentration, and the initial measurement of concentration of the first species is adjusted based on a combination of the direct and indirect concentration determination of the second species. The apparatus includes a first measurement device, which may be a colorimeter or amperometer, for measuring the diluted first species concentration; a second measurement device, which may be an indirect potentiometer, for measuring the diluted second species concentration; a third measurement device, which may be an ion selective electrode, for measuring the undiluted second species concentration; in particular embodiments, additional measurement devices, which may be a gas sensor and a spectrophotometer, for measuring the concentration of species which may complex with second species, and a computer connected to the various measurement devices.

    摘要翻译： 用于校正溶解在生物流体的水性成分中的第一水溶性物质的浓度的初始测定装置，该第一水溶性物质也包括第二水溶性物质和体积占据成分，初始测定是使用原始的 公开了已经用一定量的附加水溶液稀释以形成稀释样品的流体样品; 在未稀释的生物流体样品中测量第二水溶性物质的浓度以获得直接浓度，并使用稀释的流体样品测量以获得间接浓度，并且第一种类的浓度的初始测量为 基于第二物种的直接和间接浓度测定的组合进行调整。 该装置包括第一测量装置，其可以是色度计或电流计，用于测量稀释的第一种类浓度; 第二测量装置，其可以是用于测量稀释的第二种类浓度的间接电位计; 第三测量装置，其可以是离子选择性电极，用于测量未稀释的第二种类浓度; 在特定实施例中，附加测量装置可以是气体传感器和分光光度计，用于测量可能与第二种物质复合的物质的浓度，以及连接到各种测量装置的计算机。