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1.发明授权Method and apparatus for selecting an optimal electrode configuration of a medical electrical lead having a multiple electrode array 有权用于选择具有多个电极阵列的医用电线的最佳电极配置的方法和装置公开(公告)号：US06978178B2
公开(公告)日：2005-12-20
申请号：US10137248
申请日：2002-04-30
CPC分类号： A61N1/3686 , A61B5/04085 , A61B5/7217 , A61N1/05 , A61N1/056 , A61N1/0573 , A61N1/36185 , A61N1/3704
摘要： An electrical medical lead is provided having two or more electrodes, electrically insulated from each other and electrically coupled to individually insulated filars in a multi-filar coiled conductor. When the lead is used with a medical device equipped with a switch matrix, electrodes are selected individually or simultaneously to serve as an anode or cathode in any unipolar, bipolar or multi-polar configuration for delivering stimulation and/or sensing signals in excitable tissue. In one embodiment, a tip electrode array is expandable for improving electrode contact with targeted tissue and stabilizing lead position.
摘要翻译： 提供具有两个或更多个电极的电气医疗引线，其彼此电绝缘并且电耦合到多线圈状导体中的单独绝缘的丝状体。 当引线与配备有开关矩阵的医疗设备一起使用时，电极被单独或同时选择用作任何单极，双极或多极配置的阳极或阴极，用于在可兴奋组织中传递刺激和/或感测信号。 在一个实施例中，尖端电极阵列是可扩展的，用于改善与靶组织的电极接触和稳定引线位置。
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公开(公告)号：US08838254B2
公开(公告)日：2014-09-16
申请号：US12872352
申请日：2010-08-31
CPC分类号： A61N1/37 , A61B5/0031 , A61N1/086 , A61N1/3688 , A61N1/3718 , A61N1/37247 , G06F19/00 , G16H40/63
摘要： This disclosure describes techniques for configuring an IMD into the exposure operating mode. Prior to a medical procedure that generates a disruptive energy field, such as an MRI scan, an electronic prescription is configured to indicate that the IMD is authorized for the medical procedure that includes a disruptive energy field. The electronic prescription includes one or more designated bits within a storage element of the IMD. When the patient in which the IMD is implanted arrives for the medical procedure, a user (such as an MRI operator) interacts with a telemetry device to determine whether the electronic prescription is configured. Upon determining that the electronic prescription is configured, the IMD transitions into the exposure operating mode designed for operation in the disruptive energy field. In this manner, the electronic prescription confirms to the user that that the IMD has been checked for suitability for operation during the medical procedure.
摘要翻译： 本公开描述了将IMD配置到曝光操作模式中的技术。 在产生诸如MRI扫描的破坏性能量场的医疗过程之前，电子处方被配置为指示IMD被授权用于包括破坏性能量场的医疗程序。 电子处方包括在IMD的存储元件内的一个或多个指定位。 当植入IMD的患者到达医疗程序时，用户（例如MRI操作者）与遥测装置进行交互以确定电子处方是否被配置。 在确定电子处方被配置后，IMD转变为设计用于在破坏性能量场中操作的曝光操作模式。 以这种方式，电子处方向用户确认已经检查了IMD是否适合在医疗过程中操作。
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公开(公告)号：US20110196447A1
公开(公告)日：2011-08-11
申请号：US12872352
申请日：2010-08-31
IPC分类号： A61N1/08
CPC分类号： A61N1/37 , A61B5/0031 , A61N1/086 , A61N1/3688 , A61N1/3718 , A61N1/37247 , G06F19/00 , G16H40/63
摘要： This disclosure describes techniques for configuring an IMD into the exposure operating mode. Prior to a medical procedure that generates a disruptive energy field, such as an MRI scan, an electronic prescription is configured to indicate that the IMD is authorized for the medical procedure that includes a disruptive energy field. The electronic prescription includes one or more designated bits within a storage element of the IMD. When the patient in which the IMD is implanted arrives for the medical procedure, a user (such as an MRI operator) interacts with a telemetry device to determine whether the electronic prescription is configured. Upon determining that the electronic prescription is configured, the IMD transitions into the exposure operating mode designed for operation in the disruptive energy field. In this manner, the electronic prescription confirms to the user that that the IMD has been checked for suitability for operation during the medical procedure.
摘要翻译： 本公开描述了将IMD配置到曝光操作模式中的技术。 在产生诸如MRI扫描的破坏性能量场的医疗过程之前，电子处方被配置为指示IMD被授权用于包括破坏性能量场的医疗程序。 电子处方包括在IMD的存储元件内的一个或多个指定位。 当植入IMD的患者到达医疗程序时，用户（例如MRI操作者）与遥测装置进行交互以确定电子处方是否被配置。 在确定电子处方被配置后，IMD转变为设计用于在破坏性能量场中操作的曝光操作模式。 以这种方式，电子处方向用户确认已经检查了IMD是否适合在医疗过程中操作。
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公开(公告)号：US07233825B2
公开(公告)日：2007-06-19
申请号：US10367299
申请日：2003-02-15
申请人： David J. Jorgenson , Christopher M. Manrodt , Robert M. Ecker , Lawrence C. McClure , Charles H. Malmskog
发明人： David J. Jorgenson , Christopher M. Manrodt , Robert M. Ecker , Lawrence C. McClure , Charles H. Malmskog
IPC分类号： A61N1/36
CPC分类号： A61N1/3706 , A61N1/3718 , A61N2001/083
摘要： In an implantable medical device having an electrical lead coupled to tissue of a user and a circuit for measuring the impedance of the lead, a method and apparatus for responding to impedance variations in the lead which includes measuring the impedance of the lead while monitoring physiologic parameters of the user, detecting the presence or absence of electromagnetic interference, and if the impedance of the lead is out-of-range, determining whether the electromagnetic interference exceeds a predetermined value, and if the electromagnetic interference exceeds a predetermined value, administering a therapy to the tissue of the user.
摘要翻译： 在具有耦合到用户的组织的电引线和用于测量引线的阻抗的电路的可植入医疗设备中，一种用于响应引线中的阻抗变化的方法和装置，其包括在监测生理参数的同时测量引线的阻抗 检测电磁干扰的存在或不存在，并且如果引线的阻抗超出范围，则确定电磁干扰是否超过预定值，并且如果电磁干扰超过预定值，则施用治疗 到使用者的纸巾。
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公开(公告)号：US20110196450A1
公开(公告)日：2011-08-11
申请号：US12872375
申请日：2010-08-31
IPC分类号： A61N1/08
CPC分类号： A61N1/37 , A61B5/0031 , A61N1/086 , A61N1/3688 , A61N1/3718 , A61N1/37247 , G16H40/63
摘要： This disclosure describes techniques for configuring an IMD into the exposure operating mode. Prior to a medical procedure that generates a disruptive energy field, such as an MRI scan, an electronic prescription is configured to indicate that the IMD is authorized for the medical procedure that includes a disruptive energy field. The electronic prescription includes one or more designated bits within a storage element of the IMD. When the patient in which the IMD is implanted arrives for the medical procedure, a user (such as an MRI operator) interacts with a telemetry device to determine whether the electronic prescription is configured. Upon determining that the electronic prescription is configured, the IMD transitions into the exposure operating mode designed for operation in the disruptive energy field. In this manner, the electronic prescription confirms to the user that that the IMD has been checked for suitability for operation during the medical procedure.
摘要翻译： 本公开描述了将IMD配置到曝光操作模式中的技术。 在产生诸如MRI扫描的破坏性能量场的医疗过程之前，电子处方被配置为指示IMD被授权用于包括破坏性能量场的医疗程序。 电子处方包括在IMD的存储元件内的一个或多个指定位。 当植入IMD的患者到达医疗程序时，用户（例如MRI操作者）与遥测装置进行交互以确定电子处方是否被配置。 在确定电子处方被配置后，IMD转变为设计用于在破坏性能量场中操作的曝光操作模式。 以这种方式，电子处方向用户确认已经检查了IMD是否适合在医疗过程中操作。
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6.发明授权Method and apparatus for rate-responsive cardiac pacing using header mounted pressure wave transducer 失效使用头部安装压力波传感器的速率响应心脏起搏方法和装置公开(公告)号：US06208900B1
公开(公告)日：2001-03-27
申请号：US08623477
申请日：1996-03-28
IPC分类号： A61N1362
CPC分类号： A61N1/36542 , A61N1/3702
摘要： In a pacemaker, a method and apparatus for providing rate response in proportion to the patient's metabolic demand for cardiac output as determined in response to the patient's breathing rate or respiratory minute ventilation or contraction strength, optionally augmented by the patient's activity level. An implantable pulse generator (IPG) has one or more pacing leads having a proximal end coupled to the IPG and a distal end in contact with a patient's heart. A pressure wave transducer mounted in the IPG in relation to the proximal end of the pacing lead senses pressure waves transmitted from the distal end of the pacing lead to the proximal end thereof. The pressure waves originate from disturbances imparted to the lead by heart contractions and breathing. A further isolated, reference sensor is also incorporated into the IPG in a similar fashion. An activity signal processor is coupled to the pressure wave or reference sensor for providing a patient activity physiologic signal. A respiration signal processor is coupled to said pressure wave and reference transducers for nulling out common mode noise and providing physiologic respiration rate and/or respiratory minute ventilation signals. A contraction strength signal processor is coupled to said pressure wave and reference transducers for nulling out common mode noise and providing physiologic contraction strength signals. Pacing rate control circuitry is responsive to one or more of the physiologic signals for setting the pacing rate to meed the metabolic demand.
摘要翻译： 在起搏器中，一种方法和装置，用于根据患者的呼吸频率或呼吸分钟通气或收缩强度确定的与患者的心输出量的代谢需求成比例地提供速率响应，可选地由患者的活动水平增加。 植入式脉冲发生器（IPG）具有一个或多个起搏引线，其具有耦合到IPG的近端和与患者心脏接触的远端。 安装在IPG中的相对于起搏引线的近端的压力波换能器感测从起搏引线的远端传递到其近端的压力波。 压力波起源于通过心脏收缩和呼吸引起的引起的干扰。 另一个隔离的参考传感器也以类似的方式并入到IPG中。 活动信号处理器耦合到压力波或参考传感器，以提供患者活动生理信号。 呼吸信号处理器耦合到所述压力波和参考换能器，用于消除共模噪声并提供生理呼吸速率和/或呼吸分钟通气信号。 收缩强度信号处理器耦合到所述压力波和参考换能器，用于消除共模噪声并提供生理收缩强度信号。 起搏速率控制电路响应于一个或多个生理信号，用于将起搏速率设定为代谢需求。
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公开(公告)号：US5899927A
公开(公告)日：1999-05-04
申请号：US953092
申请日：1997-10-17
IPC分类号： A61B5/0215 , A61B5/08 , A61N1/365 , A61N1/37 , A61B5/00
CPC分类号： A61N1/3702 , A61N1/36514
摘要： In an implanted medical device, a method and apparatus for detecting pressure waves caused by movement of a body organ, muscle group, limb or the like and transmitted through a catheter or lead body to the implanted medical device employing a pressure wave transducer mounted in relation to the proximal end of the catheter or lead to detect the transmitted pressure waves. The system may also include a reference transducer having the same pressure wave response characteristics as the pressure wave transducer but isolated from the proximal connector end for providing a reference signal including common mode pressure wave noise that both transducers are simultaneously subjected to. The pressure wave signal and the reference signal are preferably amplified, bandpass filtered to the body pressure wave of interest and stored, telemetered out or used to trigger a device operation. The pressure and reference wave transducers preferably are piezoelectric crystal transducers or accelerometers in direct or indirect mechanical contact with the proximal connector end of the catheter and is encapsulated from the body within a device connector assembly. Preferably, the catheter is a lead extending into direct or indirect contact with the patient's heart. Cardiac pressure waves and respiration pressure waves are both transmitted proximally through the lead body to the pressure wave transducer. Pressure wave signals may be derived in parallel to detect particular characteristics of the cardiac and/or respiratory cycle to provide timing signal(s) for controlling the device operations.
摘要翻译： 在植入式医疗装置中，一种用于检测由身体器官，肌肉群，肢体等的运动引起的透射通过导管或引线体引起的植入医疗装置的压力波的方法和装置，所述压力波换能器安装在关系上 到导管的近端或导致检测传输的压力波。 该系统还可以包括具有与压力波传感器相同的压力波响应特性但与近端连接器端隔离的参考换能器，用于提供包括两个换能器同时经受的共模压力波噪声的参考信号。 压力波信号和参考信号优选被放大，带通滤波到感兴趣的体压波，并被存储，遥测或用于触发装置操作。 压力和参考波传感器优选地是与导管的近端连接器端直接或间接机械接触的压电晶体换能器或加速度计，并且在设备连接器组件内从主体封装。 优选地，导管是延伸成与患者心脏直接或间接接触的导线。 心脏压力波和呼吸压力波都通过引导体向近端传递到压力波传感器。 可以并行导出压力波信号以检测心脏和/或呼吸周期的特定特征，以提供用于控制装置操作的定时信号。
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8.发明授权Verification of capture using pressure waves transmitted through a pacing lead 失效使用通过起搏引线传输的压力波进行捕获验证
公开(公告)号：US5702427A
公开(公告)日：1997-12-30
申请号：US623443
申请日：1996-03-28
CPC分类号： A61N1/3702 , A61N1/36542 , A61N1/3712 , A61N1/36578
摘要： A capture verification system for a cardiac pacemaker comprising an implantable pulse generator (IPG) and one or more pacing leads having a proximal end coupled to the IPG and a distal end in contact with a patient's heart. The capture verification system employs a pressure wave sensor mounted in the IPG in relation to the proximal end of the pacing lead for sensing pressure waves transmitted from the distal end of the pacing lead to the proximal end thereof. The pressure waves include characteristic sounds of heart contraction and/or distal end lead motion caused by the contraction motion of the patient's heart that are transmitted along the lead body to the active sensor. A further isolated, reference sensor is also incorporated into the IPG in a similar fashion. Signal processors are coupled to the pressure wave and reference sensors for nulling out common mode noise.
摘要翻译： 一种用于心脏起搏器的捕获验证系统，包括可植入脉冲发生器（IPG）和一个或多个起搏引线，其具有耦合到IPG的近端和与患者心脏接触的远端。 捕获验证系统使用安装在IPG中的压力波传感器相对于起搏引线的近端，用于感测从起搏引线的远端传递到其近端的压力波。 压力波包括由沿着引导体传递到有源传感器的患者心脏的收缩运动引起的心脏收缩和/或远端引导运动的特征性声音。 另一个隔离的参考传感器也以类似的方式并入到IPG中。 信号处理器耦合到压力波和参考传感器，以消除共模噪声。
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公开(公告)号：US5350407A
公开(公告)日：1994-09-27
申请号：US998962
申请日：1992-12-30
CPC分类号： A61N1/37252 , A61N1/375 , A61N2001/37294
摘要： A method and apparatus for selectively controlling an oscillator-driven implantable stimulator to operate either in a quiescent state, in response to a command from an external communicating device, or in an active state in response either to removal of an activation pin or to an activating command from an external communicating device. Upon completion of manufacture of the stimulator, and before being placed on a shelf to await implantation in a patient, the activation pin is inserted into the stimulator and the external communicating device is triggered to send a deactivating command to the stimulator. The stimulator responds by generally disabling current sources to stimulator circuits, while maintaining current sources to a wake up circuit of the stimulator that is associated with communication operations. The stimulator is activated by subsequently transmitting an activating command from an external communicating device to the implantable stimulator, or by removing the activation pin.
摘要翻译： 一种用于响应于来自外部通信设备的命令或响应于移除激活引脚或激活的激活状态而选择性地控制振荡器驱动的可植入刺激器在静止状态下操作的方法和装置 命令从外部通信设备。 在完成刺激器的制造之后，并且在被放置在架子上以等待患者植入之前，激活销被插入到刺激器中，并且外部通信装置被触发以向激励器发送去激活命令。 刺激器通常将电流源禁用于刺激器电路，同时将电流源保持到与通信操作相关联的刺激器的唤醒电路。 刺激器通过随后从外部通信装置传送到可植入刺激器的激活命令或通过移除激活销来激活。
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