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公开(公告)号：US08491881B2
公开(公告)日：2013-07-23
申请号：US13460553
申请日：2012-04-30
IPC分类号： A61K31/74
CPC分类号： A61L26/0019 , A61K31/785 , A61L24/0021 , A61L24/043 , A61L24/06 , C08L35/04
摘要： A biological coating material that includes a polymerizable polyacrylate monomer; a volatile liquid; a polymer selected from a synthetic rubber, a natural rubber, and a thermoplastic elastomer. The biological liquid coating material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
摘要翻译： 一种生物涂料，包括可聚合的丙烯酸酯单体; 挥发性液体; 选自合成橡胶，天然橡胶和热塑性弹性体的聚合物。 生物液体涂覆材料形成薄膜形式的涂层或绷带，当施加并粘附到使用者的表面或皮肤时，该涂层或绷带可以阻止施用表面粘附到另一个表面。
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2.发明授权公开(公告)号：US08197803B2
公开(公告)日：2012-06-12
申请号：US12414708
申请日：2009-03-31
IPC分类号： A61K31/74
CPC分类号： A61L26/0019 , A61K31/785 , A61L24/0021 , A61L24/043 , A61L24/06 , C08L35/04
摘要： Liquid hemostatic coating materials comprise a cyanoacrylate monomer and a solvent system comprising a volatile, non-reactive liquid that is non-stinging and non-irritating to a user. The material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
摘要翻译： 液体止血涂层材料包括氰基丙烯酸酯单体和包含挥发性非反应性液体的溶剂系统，其对使用者是非刺激性且不刺激性的。 该材料形成薄膜形式的涂层或绷带，当涂覆和粘附到使用者的表面或皮肤时，该涂层或绷带可以阻止涂敷表面粘附到另一表面。
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公开(公告)号：US20120109036A1
公开(公告)日：2012-05-03
申请号：US13382227
申请日：2010-07-07
IPC分类号： A61L24/02 , A61M5/00 , A61M25/02 , C08F230/08 , A61F13/02
CPC分类号： C08F230/08 , A61F2013/00702 , A61L24/046 , C08L83/04 , C08L33/14
摘要： A silicone pressure sensitive adhesive with amphiphilic copolymers for maintaining adhesion in a moist environment. The amphiphilic copolymers for silicone adhesives include at least one silicone moiety and at least one hydrophilic segment. Such adhesives are applicable to securing medical devices to human skin.
摘要翻译： 具有两亲性共聚物的硅氧烷压敏粘合剂，用于在潮湿环境中保持粘合。 用于硅氧烷粘合剂的两亲性共聚物包括至少一个硅氧烷部分和至少一个亲水链段。 这种粘合剂适用于将医疗装置固定在人的皮肤上。
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公开(公告)号：US07641893B2
公开(公告)日：2010-01-05
申请号：US11465237
申请日：2006-08-17
IPC分类号： A61K31/765
CPC分类号： A61L26/0019 , A61K31/785 , A61L24/0021 , A61L24/043 , A61L24/06 , C08L35/04
摘要： Liquid hemostatic coating materials comprise a cyanoacrylate monomer and a solvent system comprising a volatile, non-reactive liquid that is non-stinging and non-irritating to a user. The material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
摘要翻译： 液体止血涂层材料包括氰基丙烯酸酯单体和包含挥发性非反应性液体的溶剂系统，其对使用者是非刺激性且不刺激性的。 该材料形成薄膜形式的涂层或绷带，当涂覆和粘附到使用者的表面或皮肤时，该涂层或绷带可以阻止涂敷表面粘附到另一表面。
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公开(公告)号：US20130150451A1
公开(公告)日：2013-06-13
申请号：US13313880
申请日：2011-12-07
CPC分类号： A01N47/44 , A61K31/155 , Y02A50/473 , A01N31/02 , A01N37/12
摘要： An antimicrobial composition with synergistic biocidal activity is described which comprises at least one antimicrobial polymeric biguanide and at least one antimicrobial vicinal diol, said vicinal diol comprises at least one monoalkyl glycol, monoalkyl glycerol, or monoacyl glycerol, to diminish or eliminate biofilm communities. Such synergistic interaction is effective in wound treatment, particularly for chronic wounds, burns and battlefield-induced wounds, as well as for disinfecting non-biological surfaces. The antimicrobial composition can also be prepared as viscous solutions or as gels. The antimicrobial composition may be added to a substrate and dried, such as to a catheter, or to a foam, or to a fiber wound dressing, or coated as a viscous solution or gel upon such devices, to provide controlled release antimicrobial activity.
摘要翻译： 描述了具有协同杀生物活性的抗微生物组合物，其包含至少一种抗微生物聚合双胍和至少一种抗微生物连位二醇，所述连位二醇包含至少一种单烷基二醇，单烷基甘油或单酰基甘油，以减少或消除生物膜群落。 这种协同相互作用在伤口治疗中是有效的，特别是对于慢性伤口，烧伤和战场引起的伤口以及用于消毒非生物表面。 抗微生物组合物也可以制备成粘稠溶液或凝胶。 抗微生物组合物可以加入到基质中并干燥，例如导管，或泡沫，或纤维伤口敷料，或在这种装置上作为粘性溶液或凝胶涂覆，以提供受控释放的抗微生物活性。
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公开(公告)号：US20120208974A1
公开(公告)日：2012-08-16
申请号：US13210038
申请日：2011-08-15
IPC分类号： C09J133/26 , C09J177/02
CPC分类号： C09J133/26 , C08F220/18 , C09J133/08 , C09J139/04 , C08F220/56
摘要： The present invention relates to amphiphilic pressure sensitive adhesives, specifically, pressure sensitive adhesives with amphiphilic copolymers which improve adhesion under moist environment. The amphiphilic copolymers comprise at least one hydrophobic acrylic monomer or oligomer and at least one hydrophilic or amphiphilic monomer or oligomer. The present invention also relates to the use of such adhesives in securing medical devices to human skin.
摘要翻译： 本发明涉及两亲压敏粘合剂，具体地说，涉及在潮湿环境下改善粘合性的两亲共聚物的压敏粘合剂。 两亲共聚物包含至少一种疏水性丙烯酸单体或低聚物和至少一种亲水或两亲性单体或低聚物。 本发明还涉及这种粘合剂在将医疗装置固定在人体皮肤上的用途。
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公开(公告)号：US20120276041A1
公开(公告)日：2012-11-01
申请号：US13460553
申请日：2012-04-30
IPC分类号： A61K31/785 , A61K31/80 , A61P7/04
CPC分类号： A61L26/0019 , A61K31/785 , A61L24/0021 , A61L24/043 , A61L24/06 , C08L35/04
摘要： A biological coating material that includes a polymerizable polyacrylate monomer; a volatile liquid; a polymer selected from a synthetic rubber, a natural rubber, and a thermoplastic elastomer. The biological liquid coating material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
摘要翻译： 一种生物涂料，包括可聚合的丙烯酸酯单体; 挥发性液体; 选自合成橡胶，天然橡胶和热塑性弹性体的聚合物。 生物液体涂覆材料形成薄膜形式的涂层或绷带，当施加并粘附到使用者的表面或皮肤时，该涂层或绷带可以阻止施用表面粘附到另一个表面。
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公开(公告)号：US10294317B2
公开(公告)日：2019-05-21
申请号：US13382227
申请日：2010-07-07
IPC分类号： A61F13/00 , A61L24/04 , C08L33/14 , C08L83/04 , C08F230/08
摘要： A silicone pressure sensitive adhesive with amphiphilic copolymers for maintaining adhesion in a moist environment. The amphiphilic copolymers for silicone adhesives include at least one silicone moiety and at least one hydrophilic segment. Such adhesives are applicable to securing medical devices to human skin.
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公开(公告)号：US07795326B2
公开(公告)日：2010-09-14
申请号：US11565453
申请日：2006-11-30
IPC分类号： A61F13/02
CPC分类号： A61L26/0009 , A61L15/26 , A61L24/0015 , A61L24/043 , A61L26/0019 , A61L26/0066 , A61L27/34 , A61L2300/404 , A61L2300/606 , C09D4/00 , Y02P20/544 , Y10S128/21 , C08L83/04
摘要： The liquid, polymer-containing coating materials of this invention comprise a polymer of a polymerizable, nitrogen-containing, hydrophilic monomer, which may give thermoresponsive properties, and which is copolymerized with a hydrophobic, polymerizable siloxy-containing monomer, in a solvent system of a volatile hydrophobic (non-polar) liquid that is non-stinging to a user. The material forms a coating or bandage in the form of a film when applied to a surface or the skin of a user.
摘要翻译： 本发明的含液体聚合物的涂料包含可聚合的含氮亲水性单体的聚合物，其可以产生热反应性，并且与含疏水性的可聚合的含甲硅烷氧基的单体共聚， 一种不刺激使用者的挥发性疏水（非极性）液体。 当施加到使用者的表面或皮肤时，该材料形成薄膜形式的涂层或绷带。
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10.发明授权公开(公告)号：US08828420B2
公开(公告)日：2014-09-09
申请号：US11611508
申请日：2006-12-15
IPC分类号： A61K9/00 , G02B1/04 , C08G77/388
CPC分类号： C08G77/388 , G02B1/043
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized siloxane prepolymer containing pendant cationic and polymerizable groups.
摘要翻译： 本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。 更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子无规共聚物。 这些性质包括用水提取聚合的医疗装置的能力。 这避免了使用本领域典型的有机溶剂。 聚合物组合物包含聚合的含有阳离子和可聚合基团的聚硅氧烷预聚物。
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