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公开(公告)号：US5522865A
公开(公告)日：1996-06-04
申请号：US322068
申请日：1994-10-12
CPC分类号： A61N1/36032 , A61N1/36185 , A61N1/37252 , H04R25/505 , H04R2460/03
摘要： A tissue stimulating system includes an external transmitter for transmitting a data signal to an implanted stimulator. The implanted stimulator includes a processor for generating stimulation signals for application to a plurality of tissue stimulating electrodes through respective isolated output channels. The implanted stimulator also includes a power supply that extracts a raw power signal from the data signal. A voltage downconverter generates at least four separate voltages from the extracted raw power signal by alternately connecting at least four capacitors in series across the raw power signal, thereby providing at least four output voltages, and then connecting the capacitors in parallel to transfer the charge stored thereon to a storage capacitor, which serves as the power source for portions of the stimulator. A selected one of the output voltages from the voltage downconverter is applied to an isolated refresh voltage capacitor in each output channel, where it controls a voltage controlled current source. The processor selectively monitors the electrodes and/or voltages generated in the stimulator and generates status indicating/measurement signals for transmission to the external transmitter. The external processor receives and processes the status indicating/measurement signals and uses the information therefrom to control the amount of power transmitted to the stimulator.
摘要翻译： 组织刺激系统包括用于将数据信号发送到植入的刺激器的外部发射器。 植入的刺激器包括用于通过相应的隔离输出通道产生刺激信号以用于多个组织刺激电极的处理器。 植入的刺激器还包括从数据信号中提取原始功率信号的电源。 电压下变频器通过在原始功率信号上交替地连接串联的至少四个电容器，从而提供至少四个输出电压，然后并联连接电容器以转移所存储的电荷，从而从提取的原始功率信号产生至少四个分离的电压 在其上用作用于刺激器的部分的电源的存储电容器。 来自电压下变频器的选择的一个输出电压被施加到每个输出通道中的隔离的刷新电压电容器，其中它控制电压控制的电流源。 处理器选择性地监视在刺激器中产生的电极和/或电压，并产生用于传输到外部发射器的状态指示/测量信号。 外部处理器接收并处理状态指示/测量信号，并使用其信息来控制发送到刺激器的功率量。
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公开(公告)号：US5776172A
公开(公告)日：1998-07-07
申请号：US450041
申请日：1995-05-25
CPC分类号： A61N1/36032 , A61N1/36185 , A61N1/37252 , H04R25/505 , H04R2460/03
摘要： An implantable cochlear stimulator (ICS) has eight output stages (212), each having a current source (212B) connected to a pair of electrodes, designated "A" and "B", through respective output coupling capacitors and an electrode switching matrix (212C). An indifferent electrode is connected to each output stage by way of an indifferent electrode switch (212D). The current source generates a precise stimulation current as a function of an analog control voltage. The analog control voltage, in turn, is generated by a logarithmic D/A converter. The D/A converter serially converts data words, received in a data frame from an external source, to respective analog control voltages that are applied sequentially to the current sources of each output stage. An output mode register (208) controls the switching matrix of each stage, as well as the indifferent electrode switch, to configure the electrodes for a desired stimulation configuration, e.g., bipolar stimulation (current flow between the pair of electrodes of the output stage), or monopolar stimulation (current flow between one of the electrodes of the output stage and the indifferent electrode). The voltage at the "A" and "B" electrode of each output stage may be selectively telemetered to the wearable system, as may the current flow through the indifferent electrode, thereby facilitating a measurement of the electrode impedance. The "A" and "B" electrodes of each output stage may be selectively shorted through a high or low resistance in order to discharge the output coupling capacitors.
摘要翻译： 植入式耳蜗刺激器（ICS）具有八个输出级（212），每个输出级通过相应的输出耦合电容和电极开关矩阵（212）连接到一对电极（A“和”B“）上， 212C）。 无电极通过无关电极开关（212D）连接到每个输出级。 电流源产生精确的刺激电流作为模拟控制电压的函数。 模拟控制电压又由对数D / A转换器产生。 D / A转换器将数据帧中从外部源接收的数据字串行地转换为顺序施加到每个输出级的当前源的相应模拟控制电压。 输出模式寄存器（208）控制每个级的开关矩阵以及无关电极开关，以将电极配置为期望的刺激配置，例如双极刺激（输出级的一对电极之间的电流） ，或单极刺激（电流在输出级的电极和无关电极之间）。 每个输出级的“A”和“B”电极处的电压可以选择性地遥测到可穿戴系统，电流可以通过无关电极，从而便于电极阻抗的测量。 每个输出级的“A”和“B”电极可以通过高电阻或低电阻选择性短路，以便放电输出耦合电容器。
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公开(公告)号：US5569307A
公开(公告)日：1996-10-29
申请号：US322066
申请日：1994-10-12
CPC分类号： A61N1/36032 , A61N1/36185 , A61N1/37252 , H04R25/505 , H04R2460/03
摘要： An external wearable processor (WP) of a cochlear stimulating system transmits a data signal to an implanted cochlear stimulator (ICS). The ICS is controlled through the data signal so that cochlear stimulation is provided by the ICS only after a determination is made that the WP is in proper signal contact therewith, and that the ICS is functioning properly. The ICS extracts a raw power signal from the data signal and generates different operating voltages from the extracted raw power signal. A detector generates a power bad signal whenever one of the operating voltages is less than a reference voltage. The ICS also detects and generates a carrier detect signal when the data signal is being received. Clock signals are generated within the ICS, and a phase locked loop (PLL) lock signal is generated when the clock signals are phase locked to the data signal. ICS circuitry further checks the parity of the incoming data signal and generates a parity alarm signal whenever a parity error is detected. A back telemetry carrier signal is transmitted from the ICS only when a prescribed combination of the carrier detect, PLL lock, power bad, and parity alarm signals exist. The back telemetry carrier signal, when received at the WP, is used as a handshake signal to signal the WP that the ICS is in proper signal communication with the WP, and that operation of the ICS can proceed.
摘要翻译： 耳蜗刺激系统的外部可穿戴处理器（WP）将数据信号传输到植入式耳蜗刺激器（ICS）。 通过数据信号控制ICS，使得只有在确定WP与其正确的信号接触之后，ICS才提供耳蜗刺激，并且ICS正常工作。 ICS从数据信号中提取原始功率信号，并从提取的原始功率信号中产生不同的工作电压。 每当工作电压之一小于参考电压时，检测器产生电力不良信号。 当接收到数据信号时，ICS还检测并产生载波检测信号。 在ICS内产生时钟信号，并且当时钟信号被锁相到数据信号时，产生锁相环（PLL）锁定信号。 ICS电路进一步检查输入数据信号的奇偶性，并且每当检测到奇偶校验错误时产生奇偶校验报警信号。 只有当载波检测，PLL锁定，电源不良和奇偶校验警报信号存在规定的组合时，才从ICS发送后向遥测载波信号。 背面遥测载波信号在WP接收时被用作握手信号，以向WP通知ICS与WP进行适当的信号通信，并且ICS的操作可以进行。
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公开(公告)号：US5938691A
公开(公告)日：1999-08-17
申请号：US103264
申请日：1998-06-23
CPC分类号： A61N1/3787 , A61N1/36032 , H04R25/505 , A61N1/37252 , H04R2460/03
摘要： A cochlea stimulation system includes a patient wearable system comprising an externally wearable signal processor (WP) and a headpiece in electronic communication with an implanted cochlear stimulator (ICS). The ICS comprises eight output stages each having two electrically isolated capacitor-coupled electrodes, designated "A" and "B", circuits for monitoring the voltages on these electrodes, and circuits for both transmitting status information to and receiving control information from the WP. Based upon information received from the WP, a processor within the ICS can control both the frequency and the widths of the output stimulation pulses applied to the electrodes and may select which electrodes to monitor. The ICS receives power and data signals telemetrically through the skin from the WP. To save power, the ICS may be "powered down" by the WP based upon the absence of audio information or "powered up" if audio is present. The WP communicates with the headpiece over a co-axial cable using one frequency for transmitting signals and a second different frequency for receiving signals.
摘要翻译： 耳蜗刺激系统包括患者穿戴式系统，其包括外部穿戴式信号处理器（WP）和与植入式耳蜗刺激器（ICS）电子通信的头盔。 ICS包括八个输出级，每个输出级具有两个电隔离的电容器耦合电极，标号为“A”和“B”，用于监视这些电极上的电压的电路，以及用于向WP发送状态信息和从WP接收控制信息的电路。 基于从WP接收的信息，ICS内的处理器可以控制施加到电极的输出刺激脉冲的频率和宽度，并且可以选择要监测哪些电极。 ICS通过WP的皮肤遥测地接收电力和数据信号。 为了节省电力，ICS可以基于没有音频信息或者如果存在音频“加电”，则由WP“掉电”。 WP通过同轴电缆与头戴式耳机通信使用一个频率传输信号和第二个不同的频率用于接收信号。
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5.发明授权Multichannel implantable cochlear stimulator having programmable bipolar, monopolar or multipolar electrode configurations 失效具有可编程双极，单极或多极电极配置的多通道植入式耳蜗刺激器
公开(公告)号：US5531774A
公开(公告)日：1996-07-02
申请号：US322065
申请日：1994-10-12
CPC分类号： A61N1/36032 , A61N1/36185 , A61N1/37252 , H04R25/505 , H04R2460/03
摘要： An implantable cochlear stimulator (ICS) has eight output stages (212), each having a programmable current source (212B) connected to a pair of electrodes, designated "A" and "B", through respective output coupling capacitors and an electrode switching matrix (212C). An indifferent electrode is connected to each output stage by way of an indifferent electrode switch (212D). An output mode register (208) controls the switching matrix of each stage, as well as the indifferent electrode switch, to configure the electrodes for: (1) bipolar stimulation (current flow between the pair of electrodes of the output stage), (2) monopolar A stimulation (current flow between the "A" electrode of the output stage and the indifferent electrode), (3) monopolar B stimulation (current flow between the "B" electrode of the output stage and the indifferent electrode), or (4) multipolar stimulation (current flow between the "A" or "B" electrode of one output stage and the "A" or "B" electrode of another output stage). The mode register is set by way of a command word, transmitted to the ICS from an external wearable system (10) as part of a data frame. The voltage at the "A" and "B" electrode of each output stage may be selectively telemetered to the wearable system, as may the current flow through the indifferent electrode, thereby facilitating a measurement of the electrode impedance. The "A" and "B" electrodes of each output stage may be selectively shorted through a high or low resistance in order to discharge the output coupling capacitors.
摘要翻译： 可植入人工耳蜗刺激器（ICS）具有八个输出级（212），每个输出级通过相应的输出耦合电容器和电极开关矩阵连接到一对电极（A“和”B“）上，每个具有可编程电流源（212B） （212℃）。 无电极通过无关电极开关（212D）连接到每个输出级。 输出模式寄存器（208）控制每个级的开关矩阵以及无关电极开关，以配置电极：（1）双极刺激（输出级的一对电极之间的电流），（2 ）单极A刺激（输出级“A”电极与无关电极之间的电流），（3）单极B刺激（输出级“B”电极与无关电极之间的电流）或（ 4）多极刺激（一个输出级的“A”或“B”电极与另一个输出级的“A”或“B”电极之间的电流）。 模式寄存器通过命令字设置，作为数据帧的一部分从外部可穿戴系统（10）发送到ICS。 每个输出级的“A”和“B”电极处的电压可以选择性地遥测到可穿戴系统，电流可以通过无关电极，从而便于电极阻抗的测量。 每个输出级的“A”和“B”电极可以通过高电阻或低电阻选择性短路，以便放电输出耦合电容器。
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公开(公告)号：US20080092911A1
公开(公告)日：2008-04-24
申请号：US10920570
申请日：2004-08-18
申请人： Joseph H. Schulman , John C. Gord , James H. Wolfe
发明人： Joseph H. Schulman , John C. Gord , James H. Wolfe
IPC分类号： A61B19/00
CPC分类号： A61N1/37288 , A61B5/0008 , A61B5/0028 , A61B5/0031 , A61B5/053 , A61B5/07 , A61B5/076 , A61B5/1071 , A61B5/145 , A61B5/14532 , A61B5/1473 , A61B2560/0209 , A61B2560/0219 , A61B2562/08 , A61F2/72 , A61F2002/5058 , A61F2002/704 , A61F2002/705 , A61N1/37205 , A61N1/3787
摘要： A system for monitoring temperature in a body, the system comprising at least one implantable device, wherein the implantable device(s) is operable to sense temperature in the body and to generate status signals based on the sensed temperature in the body. The system further comprising a system control unit for wirelessly communicating with the implantable device(s), and the system control unit comprising a signal receiver for receiving the status signals, and also a programmable controller for producing notification signals based on the received status signals. A notification unit can alternatively communicate with the system control unit or the implantable device(s) for disclosing the sensed body temperature based on the notification signals.
摘要翻译： 一种用于监测身体温度的系统，所述系统包括至少一个可植入装置，其中所述可植入装置可操作以感测身体中的温度并基于身体中感测的温度产生状态信号。 所述系统还包括用于与所述可植入装置进行无线通信的系统控制单元，所述系统控制单元包括用于接收状态信号的信号接收器，以及用于基于接收的状态信号产生通知信号的可编程控制器。 通知单元还可以与系统控制单元或可植入装置通信，用于基于通知信号公开感测体温。
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公开(公告)号：US06799070B2
公开(公告)日：2004-09-28
申请号：US10056848
申请日：2002-01-23
申请人： James H. Wolfe , John C. Gord , Joseph H. Schulman
发明人： James H. Wolfe , John C. Gord , Joseph H. Schulman
IPC分类号： A61N136
CPC分类号： A61N1/025 , A61N1/3706 , A61N1/378 , A61N1/3782 , A61N1/3981 , H02J7/345 , H02M3/07
摘要： Battery driven voltage control circuitry charges an output capacitor, which periodically supplies a current pulse. The circuitry converts battery voltage VBAT to a charging voltage VUPC based upon programmed parameters and the voltage VCOMPL at the capacitor. The circuitry includes a voltage converter for multiplying VBAT to produce VUPC. VCOMPL is sampled to determine its “droop” at the end of an output current pulse. If the droop is lower than a threshold, then the voltage converter increases the charging voltage. If the droop is above a threshold, then the voltage converter reduces the charging voltage. This feedback maintains the output voltage within an acceptable operating range to produce an efficacious output current pulse for stimulation without causing unproductive energy loss. In order to avoid premature depletion of battery energy, VUPC is compared with VCOMPL to determine the optimum clock rate to be used to convert VBAT to VUPC.
摘要翻译： 电池驱动电压控制电路对输出电容充电，周期性地提供电流脉冲。 该电路根据编程参数和电容器上的电压VCOMPL将电池电压VBAT转换为充电电压VUPC。 该电路包括用于乘以VBAT以产生VUPC的电压转换器。 VCOMPL被采样以确定其在输出电流脉冲结束时的“下降”。 如果下降低于阈值，则电压转换器增加充电电压。 如果下降高于阈值，则电压转换器降低充电电压。 该反馈将输出电压维持在可接受的工作范围内，以产生用于刺激的有效输出电流脉冲，而不会导致非生产性能量损失。 为了避免电池能量过早耗尽，VUPC与VCOMPL进行比较，以确定用于将VBAT转换为VUPC的最佳时钟速率。
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公开(公告)号：US08555894B2
公开(公告)日：2013-10-15
申请号：US10920570
申请日：2004-08-18
申请人： Joseph H. Schulman , John C. Gord , James H. Wolfe
发明人： Joseph H. Schulman , John C. Gord , James H. Wolfe
IPC分类号： A61B19/00
CPC分类号： A61N1/37288 , A61B5/0008 , A61B5/0028 , A61B5/0031 , A61B5/053 , A61B5/07 , A61B5/076 , A61B5/1071 , A61B5/145 , A61B5/14532 , A61B5/1473 , A61B2560/0209 , A61B2560/0219 , A61B2562/08 , A61F2/72 , A61F2002/5058 , A61F2002/704 , A61F2002/705 , A61N1/37205 , A61N1/3787
摘要： A system for monitoring temperature in a body, the system comprising at least one implantable device, wherein the implantable device(s) is operable to sense temperature in the body and to generate status signals based on the sensed temperature in the body. The system further comprising a system control unit for wirelessly communicating with the implantable device(s), and the system control unit comprising a signal receiver for receiving the status signals, and also a programmable controller for producing notification signals based on the received status signals. A notification unit can alternatively communicate with the system control unit or the implantable device(s) for disclosing the sensed body temperature based on the notification signals.
摘要翻译： 一种用于监测身体温度的系统，所述系统包括至少一个可植入装置，其中所述可植入装置可操作以感测身体中的温度并基于身体中感测的温度产生状态信号。 所述系统还包括用于与所述可植入装置进行无线通信的系统控制单元，所述系统控制单元包括用于接收状态信号的信号接收器，以及用于基于接收的状态信号产生通知信号的可编程控制器。 通知单元还可以与系统控制单元或可植入装置通信，用于基于通知信号公开感测体温。
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9.发明授权
公开(公告)号：US5626629A
公开(公告)日：1997-05-06
申请号：US456141
申请日：1995-05-31
CPC分类号： H04R25/70 , A61N1/36032 , H04R25/505
摘要： A method and apparatus for fitting an auditory stimulation system involve, in one embodiment, coupling a programmer unit to an implanted unit implanted in the patient; prompting and/or assisting the operator to make and enter an objective or other measurement; receiving the objective measurements into the programmer unit; and determining an estimated threshold stimulation current for an electrode channel of the implanted unit as a function of the objective measurement. In another embodiment, the method and apparatus involve coupling a programmer unit to an implanted unit implanted in the patient; stimulating the patient with a speech signal; and displaying, in real time, a graphical representation of the speech signal using the programmer unit.
摘要翻译： 在一个实施例中，用于装配听觉刺激系统的方法和装置涉及将编程器单元耦合到植入患者体内的植入单元; 提示和/或协助操作人员进行目标或其他测量; 将客观测量结果接收到编程器单元中; 以及根据所述客观测量确定所述植入单元的电极通道的估计阈值刺激电流。 在另一个实施例中，所述方法和装置包括将编程器单元耦合到植入患者体内的植入单元; 用语音信号刺激患者; 并且使用编程器单元实时地显示语音信号的图形表示。
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