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公开(公告)号：US07439821B2
公开(公告)日：2008-10-21
申请号：US11228751
申请日：2005-09-16
申请人： Joseph H. Schulman , John C. Gord
发明人： Joseph H. Schulman , John C. Gord
CPC分类号： H02J1/08 , H02M3/33569 , H02M3/337
摘要： A DC to DC transmission system includes at least three conductors between a source and a sink, a first switch which alternately connects each conductor to the source, a second switch which alternately connects each conductor to the sink. The switches are synchronized such that one conductor is alternately coupled between the same polarity side of the source and sink and another conductor is alternately coupled between the other polarity side of the source and sink. The alternating connection between the conductors and source and sink may be undertaken at a wide range of frequencies.
摘要翻译： DC至DC传输系统包括在源和宿之间的至少三个导体，将每个导体交替地连接到源的第一开关，将每个导体交替地连接到水槽的第二开关。 开关是同步的，使得一个导体交替地耦合在源极和漏极的相同极性侧之间，另一个导体交替地耦合在源极和漏极的另一个极性侧之间。 导体和源极和吸收器之间的交替连接可以在宽的频率范围内进行。
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公开(公告)号：US07079881B2
公开(公告)日：2006-07-18
申请号：US10288038
申请日：2002-11-04
IPC分类号： A61N5/00
CPC分类号： A61N1/36585 , A61B5/0031 , A61B5/14532 , A61B5/14546 , A61B5/14865 , A61B5/4839 , A61B2560/0219 , A61M5/1723 , A61N1/05 , A61N1/372 , A61N1/3754 , H01L23/3107 , H01L29/0657 , H01L2924/0002 , H01L2924/19041 , H01L2924/00
摘要： An implantable substrate sensor has electronic circuitry and electrodes formed on opposite sides of a substrate. A protective coating covers the substrate, effectively hermetically sealing the electronic circuitry under the coating. Exposed areas of the electrodes are selectively left uncovered by the protective coating, thereby allowing such electrodes to be exposed to body tissue and fluids when the sensor is implanted in living tissue. The substrate on which the electronic circuitry and electrodes are formed is the same substrate or “chip” on which an integrated circuit (IC) is formed, which integrated circuit contains the desired electronic circuitry. Such approach eliminates the need for an hermetically sealed lid or cover to cover hybrid electronic circuitry, and allows the sensor to be made much thinner than would otherwise be possible. In one embodiment, two such substrate sensors may be placed back-to-back, with the electrodes facing outward. As required, capacitors that form part of the sensor's electronic circuits are formed on the substrate by placing metalization layers and a dielectric in vacant areas of the substrate surface.
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3.发明授权Multi-mode crystal oscillator system selectively configurable to minimize power consumption or noise generation 有权多模式晶体振荡器系统可选择配置以最小化功耗或产生噪声公开(公告)号：US06959217B2
公开(公告)日：2005-10-25
申请号：US10280841
申请日：2002-10-24
申请人： Gregory Jay DelMain , John C. Gord , Paul DeRocco
发明人： Gregory Jay DelMain , John C. Gord , Paul DeRocco
CPC分类号： A61N1/08 , H03L7/00 , Y10S323/911
摘要： The present invention is directed to a multi-mode crystal oscillator system selectively configurable to minimize power consumption or noise generation. Such a system is particularly applicable to the communication system of an implantable device, e.g., the microstimulator/sensor device described in U.S. Pat. Nos. 6,164,284 and 6,185,452. In such devices, their small size limits the size of the battery contained within and thus makes it essential to minimize power consumption. Additionally, the small size and battery capacity result in a limited transmission power. Furthermore, the small size limits the antenna efficiency which makes it desirable to limit any noise generation to maximize the signal-to-noise level of the resulting receive signal. Accordingly, embodiments of the present invention alternatively supply power to the oscillator in either a first mode that minimizes power consumption or a second mode that minimizes noise generation.
摘要翻译： 本发明涉及一种多模式晶体振荡器系统，其选择性地可配置以最小化功率消耗或产生噪声。 这样的系统特别适用于可植入装置的通信系统，例如美国专利No. 6,164,284和6,185,452号。 在这样的设备中，它们的小尺寸限制了包含在其中的电池的尺寸，并且因此使得最小化功率消耗成为必要。 此外，小尺寸和电池容量导致有限的发射功率。 此外，小尺寸限制了天线效率，这使得期望限制任何噪声产生以使得到的接收信号的信噪比水平最大化。 因此，本发明的实施例可以以最小化功耗的第一模式或使噪声产生最小化的第二模式向振荡器供电。
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公开(公告)号：US06809507B2
公开(公告)日：2004-10-26
申请号：US10034338
申请日：2001-12-28
申请人： Wayne A. Morgan , David Choy , John C. Gord , Rajiv Shah
发明人： Wayne A. Morgan , David Choy , John C. Gord , Rajiv Shah
IPC分类号： G01N2700
摘要： An electronic circuit for sensing an output of a sensor having at least one electrode pair and circuitry for obtaining and processing the sensor output. The electrode pair may be laid out such that one electrode is wrapped around the other electrode in a U-shaped fashion. The electronic circuitry may include, among other things, a line interface for interfacing with input/output lines, a rectifier in parallel with the line interface, a counter connected to the line interface and a data converter connected to the counter and the electrode pair. The data converter may be a current-to-frequency converter. In addition, the rectifier may derive power for the electronic circuit from communication pulses received on the input/output lines.
摘要翻译： 一种用于感测具有至少一个电极对的传感器的输出和用于获得和处理传感器输出的电路的电子电路。 可以布置电极对，使得一个电极以U形方式缠绕在另一个电极周围。 电子电路可以包括用于与输入/输出线接口的线路接口，与线路接口并联的整流器，连接到线路接口的计数器和连接到计数器和电极对的数据转换器。 数据转换器可以是电流 - 频率转换器。 此外，整流器可以从输入/输出线上接收的通信脉冲导出电子电路的功率。
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5.发明授权Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods 有权使用具有预定义的接收听觉周期的遥测系统的动态医疗装置和方法公开(公告)号：US06733446B2
公开(公告)日：2004-05-11
申请号：US09768042
申请日：2001-01-22
IPC分类号： A01B500
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： An implanted medical device (e.g. infusion pump) and an external device communicate with one another via telemetry messages that are receivable only during windows or listening periods. Each listening period is open for a prescribed period of time and is spaced from successive listening periods by an interval. The prescribed period of time is typically kept small to minimize power consumption. To increase likelihood of successful communication, the window may be forced to an open state, by use of an attention signal, in anticipation of an incoming message. To further minimize power consumption, it is desirable to minimize use of extended attention signals, which is accomplished by the transmitter maintaining an estimate of listening period start times and attempting to send messages only during listening periods. In the communication device, the estimate is updated as a result of information obtained with the reception of each message from the medical device.
摘要翻译： 植入式医疗装置（例如输液泵）和外部装置通过仅在窗口或收听期间可接收的遥测信息相互通信。 每个聆听期间开放一段规定的时间段，并且与连续的收听周期间隔一段间隔。 规定的时间段通常保持较小以最小化功耗。 为了增加成功通信的可能性，可以通过使用注意信号将窗口强制为打开状态，以预期传入的消息。 为了进一步最小化功率消耗，期望最小化延长的关注信号的使用，其由发射机维持听觉周期开始时间的估计并且仅在收听期间尝试发送消息来实现。 在通信装置中，作为来自医疗装置的每个消息的接收获得的信息的结果，更新估计。
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公开(公告)号：US06564807B1
公开(公告)日：2003-05-20
申请号：US09677384
申请日：2000-09-30
IPC分类号： A61B1900
CPC分类号： A61N1/37211 , A61B5/0031 , A61B5/053 , A61B5/07 , A61B5/145 , A61B5/14532 , A61B5/4519 , A61B5/4528 , A61B2560/0219 , A61B2562/08 , A61F2/72 , A61F2002/5058 , A61F2002/704 , A61F2002/705 , A61N1/37205 , A61N1/37252 , A61N1/37288 , A61N1/3787
摘要： A system for monitoring and/or affecting parameters of a patient's body and more particularly to such a system comprised of a system control unit (SCU) and one or more other devices, preferably battery-powered, implanted in the patient's body, i.e., within the envelope defined by the patient's skin. Each such implanted device is configured to be monitored and/or controlled by the SCU via a wireless communication channel. In accordance with the invention, the SCU comprises a programmable unit capable of (1) transmitting commands to at least some of a plurality of implanted devices and (2) receiving data signal from at least some of those implanted devices. In accordance with a preferred embodiment, the system operates in closed loop fashion whereby the commands transmitted by the SCU are dependent, in part, on the content of the data signals received by the SCU.
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公开(公告)号：US06238365B1
公开(公告)日：2001-05-29
申请号：US09077250
申请日：1999-02-05
IPC分类号： A61M3700
CPC分类号： A61M13/003
摘要： Disclosed is a device for insufflating gas into a corporal cavity of a human or animal body having a connection for a gas source, a measuring unit provided with sensors for the fill gas pressure and the fill gas flow, which are disposed outside said corporal cavity, and a control unit, to which the output signal of the sensors are applied, and which triggers a pressure regulator which reduces or regulates the fill pressure of the gas source to an insufflation pressure (desired gas pressure), which can be set, and a flow regulator which regulates the fill gas flow to a value (desired gas flow), which can be set.
摘要翻译： 公开了一种用于将气体吹入人或动物体的具有气源连接的体腔的装置，设置有设置在所述体腔外部的填充气体压力和填充气体流量的传感器的测量单元， 以及控制单元，传感器的输出信号被施加到该控制单元，并且其触发压力调节器，其将气体源的填充压力减小或调节到可设定的吹入压力（所需气体压力） 流量调节器，其将填充气体流量调节到可以设定的值（所需气体流量）。
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公开(公告)号：US06185452B2
公开(公告)日：2001-02-06
申请号：US09030106
申请日：1998-02-25
IPC分类号： A61N130
CPC分类号： A61B5/0031 , A61B5/053 , A61B5/07 , A61B5/145 , A61B5/14532 , A61B5/4519 , A61B2560/0219 , A61B2560/063 , A61B2562/08 , A61F2/72 , A61F2002/5058 , A61F2002/704 , A61F2002/705 , A61N1/37205 , A61N1/3787
摘要： A device configured for implanting beneath a patient's skin for the purpose of tissue, e.g., nerve or muscle, stimulation and/or parameter monitoring and/or data communication. Devices in accordance with the invention are comprised of a sealed housing, typically having an axial dimension of less than 60 mm and a lateral dimension of less than 6 mm, containing a power source for powering electronic circuitry within including a controller, an address storage means, a data signal receiver and an input/output transducer. When used as a stimulator, such a device is useful in a wide variety of applications to stimulate nerves and associated neural pathways, e.g., to decrease or relieve pain, stimulate specific muscles or organs to better carry out a body function (e.g., to exercise weak or unconditioned muscles or to control urinary incontinence), and the like. Alternatively, devices of the present invention are configurable to monitor a biological parameter or to operate as a transponder to retransmit received command messages.
摘要翻译： 一种被配置为植入患者皮肤下面以用于组织例如神经或肌肉，刺激和/或参数监测和/或数据通信的装置。 根据本发明的装置包括通常具有小于60mm的轴向尺寸和小于6mm的横向尺寸的密封壳体，其包含用于为包括控制器的电子电路供电的电源，地址存储装置 ，数据信号接收器和输入/输出换能器。 当用作刺激器时，这种装置可用于各种应用以刺激神经和相关神经通路，例如减轻或缓解疼痛，刺激特定的肌肉或器官以更好地进行身体功能（例如运动 弱或无条件肌肉或控制尿失禁）等。 或者，本发明的装置可配置为监测生物参数或作为应答器操作以重新发送所接收的命令消息。
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9.发明授权
公开(公告)号：US5999848A
公开(公告)日：1999-12-07
申请号：US928867
申请日：1997-09-12
申请人： John C. Gord , Joseph H. Schulman
发明人： John C. Gord , Joseph H. Schulman
CPC分类号： A61B5/14865 , A61N1/36585 , A61N1/372 , A61M5/1723 , H01L2924/19041
摘要： An implantable sensor/stimulator is connectable to a controller using just two conductors, which two conductors carry both operating power and data (data commands and/or measured data) between the sensor/stimulator and control circuit. Each sensor/stimulator may be serially connected to another sensor/stimulator, again using only two conductors, thereby allowing a "daisy chain" of such sensors/stimulators to be formed. Each sensor/stimulator in the daisy chain is individually addressable by the control circuit. Input data is sent to the sensors over the two conductors using a phase-modulated biphasic modulation scheme, which scheme also provides operating power for each sensor/stimulator connected to the two conductors. Output data is sent from the sensors to the controller over the same two conductors using a pulse-position presence/absence modulation scheme. The data transmission schemes provide a very high signal-to-noise ratio. Each sensor/stimulator includes a power rectifier circuit, a line interface circuit, a state machine controller, at least one sensor that generates an analog output current as a function of a sensed parameter, a low power current-to-frequency converter circuit, and a counter circuit.
摘要翻译： 可植入的传感器/刺激器只能使用两根导体连接到一个控制器上，两根导体在传感器/刺激器和控制电路之间承载工作电源和数据（数据指令和/或测量数据）。 每个传感器/刺激器可以连续地连接到另一传感器/刺激器，再次仅使用两个导体，从而形成这种传感器/刺激器的“菊花链”。 菊花链中的每个传感器/刺激器都可以通过控制电路单独寻址。 使用相位调制的双相调制方案，通过两个导线将输入数据发送到传感器，该方案还为连接到两个导体的每个传感器/刺激器提供工作电源。 使用脉冲位置存在/不存在调制方案，通过相同的两个导体从传感器向控制器发送输出数据。 数据传输方案提供了非常高的信噪比。 每个传感器/刺激器包括功率整流器电路，线路接口电路，状态机控制器，至少一个传感器，其产生作为感测参数的函数的模拟输出电流，低功率电流 - 频率转换器电路，以及 一个计数器电路。
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10.发明授权
公开(公告)号：US5603726A
公开(公告)日：1997-02-18
申请号：US23584
申请日：1993-02-26
CPC分类号： A61N1/37252 , A61N1/36032 , A61N1/36185 , H04R25/505 , H04R2225/67 , H04R2460/03
摘要： A tissue stimulating system including an external transmitter for transmitting data to an implanted stimulator including a processor for generating stimulation signals for application to a plurality of tissue stimulating electrodes. The processor selectively monitors the electrodes and/or voltages generated in the stimulator and generates stimulator status indicating signals for transmission to the external transmitter. The external processor receives and processes such status indicating signals.
摘要翻译： 一种组织刺激系统，包括用于向包括用于产生用于施加到多个组织刺激电极的刺激信号的处理器的植入刺激器传送数据的外部发射器。 处理器选择性地监视在刺激器中产生的电极和/或电压，并产生指示用于传输到外部发射器的信号的刺激器状态。 外部处理器接收并处理这种状态指示信号。
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