Determination of single nucleotide polymorphisms useful to predict response for glatiramer acetate
    1.
    发明授权
    Determination of single nucleotide polymorphisms useful to predict response for glatiramer acetate 有权
    用于预测醋酸格拉默的反应的单核苷酸多态性的测定

    公开(公告)号:US09499868B2

    公开(公告)日:2016-11-22

    申请号:US14467954

    申请日:2014-08-25

    IPC分类号: A61K38/16 C12Q1/68 A61K45/06

    摘要: This invention provides a method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple sclerosis with a pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier, comprising the steps of 1) identifying whether the human subject is a predicted responder to glatiramer acetate by determining the genotype of the subject at one or more single nucleotide polymorphisms (SNPs) selected from the group consisting of the SNPs in Group 1; and 2) administering the pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier to the subject only if the subject is identified as a predicted responder to glatiramer acetate.

    摘要翻译: 本发明提供了一种治疗患有多发性硬化的人类受试者或与多发性硬化一致的单一临床攻击的方法,所述药物组合物包含乙酸格拉默和药学上可接受的载体,包括以下步骤:1)鉴定人受试者是否为预测 通过在选自组1中的SNP的一个或多个单核苷酸多态性(SNP)上确定受试者的基因型来响应乙酸格拉司坦; 以及2)如果将受试者鉴定为乙酸格拉默的预测应答者,则向受试者施用包含乙酸格拉默和药学上可接受的载体的药物组合物。

    FOOD CONTAINER WITH MEDIA PLAYER
    2.
    发明申请
    FOOD CONTAINER WITH MEDIA PLAYER 失效
    食品容器与媒体播放器

    公开(公告)号:US20120234704A1

    公开(公告)日:2012-09-20

    申请号:US13329997

    申请日:2011-12-19

    IPC分类号: B65D79/00

    CPC分类号: A45C15/00 A45C11/20 H04R1/028

    摘要: Embodiments of a food container including a media player are provided. In some embodiments, the food container has an exterior, and the food container comprises at least one compartment sized and dimensioned to accommodate food. Additionally, the food container includes a media player configured to play media content. The container and/or media player includes at least one device that serves as an input device to select media content in the media player of for later play and activation device to activate the play of the selected media content. In another embodiment the container and/or media player includes two devices, one to select media content and another to activate play of the selected media content. The media content can be, for example, a message from a parent or other meal maker to a child for later play by the child during the day.

    摘要翻译: 提供了包括媒体播放器的食物容器的实施例。 在一些实施例中,食物容器具有外部,并且食物容器包括尺寸和尺寸适于容纳食物的至少一个隔室。 另外,食品容器包括被配置为播放媒体内容的媒体播放器。 容器和/或媒体播放器包括用作输入设备的至少一个设备,用于选择媒体播放器中的媒体内容以供稍后播放和激活设备激活所选择的媒体内容的播放。 在另一个实施例中,容器和/或媒体播放器包括两个设备,一个用于选择媒体内容,另一个用于激活所选择的媒体内容的播放。 媒体内容可以是例如来自父母或其他膳食者给孩子的消息,以供儿童在白天玩耍。

    METHOD AND SYSTEM FOR ENHANCED BASIC SERVICE SET TRANSITION FOR A HIGH THROUGHPUT WIRELESS LOCAL AREA NETWORK
    5.
    发明申请
    METHOD AND SYSTEM FOR ENHANCED BASIC SERVICE SET TRANSITION FOR A HIGH THROUGHPUT WIRELESS LOCAL AREA NETWORK 审中-公开
    用于高速无线局域网的增强基本服务设置过渡的方法和系统

    公开(公告)号:US20070258384A1

    公开(公告)日:2007-11-08

    申请号:US11680892

    申请日:2007-03-01

    IPC分类号: H04J3/14

    摘要: A wireless local area network (WLAN) includes at least one high throughput-enabled access point (AP) and at least one high throughput-enabled station (STA). A STA and a target AP communicate high throughput-related information and the STA performs a basic service set (BSS) transition to the target AP based on the high throughput-related information. The high throughput-related information may be included in an IEEE 802.11r, 802.11k, or 802.11v signaling message. The STA may send measurement reports for an extended range and a normal range of an AP separately, or may send a combined measurement report for an extended range and a normal range of an AP. A network management entity may obtain current status information of the STA and the AP regarding high throughput capabilities, features and parameters and selectively enable and disable at least one of the high throughput capabilities, features and parameters of the STA and the AP.

    摘要翻译: 无线局域网(WLAN)包括至少一个高吞吐量使能接入点(AP)和至少一个高吞吐量使能站(STA)。 STA和目标AP通信高吞吐量相关信息,并且STA基于高吞吐量相关信息执行到目标AP的基本服务集(BSS)转换。 高吞吐量相关信息可以包括在IEEE 802.11r,802.11k或802.11v信令消息中。 STA可以单独发送AP的扩展范围和正常范围的测量报告,或者可以发送AP的扩展范围和正常范围的组合测量报告。 网络管理实体可以获得关于高吞吐量能力,特征和参数的STA和AP的当前状态信息,并且选择性地启用和禁用STA和AP的高吞吐能力,特征和参数中的至少一个。

    METHOD AND SIGNALING PROCEDURE FOR TRANSMISSION OPPORTUNITY USAGE IN A WIRELESS MESH NETWORK
    6.
    发明申请
    METHOD AND SIGNALING PROCEDURE FOR TRANSMISSION OPPORTUNITY USAGE IN A WIRELESS MESH NETWORK 有权
    无线网路传输机会使用的方法与信令处理

    公开(公告)号:US20070248117A1

    公开(公告)日:2007-10-25

    申请号:US11739413

    申请日:2007-04-24

    IPC分类号: H04J3/22

    摘要: In accordance with a preferred embodiment, the present invention comprises a method for using the remaining TxOP time by the peer node to forward traffic to a different destination, a method for using the remaining TxOP time by the original node to send traffic to a different destination, a method for using the remaining TxOP time by a neighbor to send traffic to the original node, a method for using the remaining TxOP time by a neighbor to send traffic to another node, a method to signal the reuse rules of the remaining TxOP time, and a method to efficiently relinquish/truncate a TxOP to reset the NAV for the neighborhood.

    摘要翻译: 根据优选实施例,本发明包括一种用于由对等节点将剩余的TxOP时间用于将业务转发到不同目的地的方法,用于由原始节点使用剩余TxOP时间以将流量发送到不同目的地的方法 用于由邻居使用剩余的TxOP时间来向原始节点发送业务的方法,用于由邻居将剩余的TxOP时间用于向另一个节点发送业务的方法,用于发送剩余TxOP时间的重用规则的方法 ,以及有效地放弃/截断TxOP以重置邻域的NAV的方法。

    Compositions for preventing hormone induced adverse effects
    7.
    发明授权
    Compositions for preventing hormone induced adverse effects 有权
    用于预防激素诱发的不良反应的组合物

    公开(公告)号:US07144586B2

    公开(公告)日:2006-12-05

    申请号:US09799251

    申请日:2001-03-05

    IPC分类号: A61K9/20 A61K31/56 A01N45/00

    摘要: A unit dosage form suitable for once daily administration to a human comprising a physiologically effective amount of at least one hormone selected from the group consisting of steroidal estrogen, estradiol, estrone, medroxyprogesterone, norethindrone, norethisterone, progestin, norgestrel, and progesterone, and at least one carotenoid wherein the carotenoid is in an amount effective to prevent the adverse effects which may result from the administration of the hormone.

    摘要翻译: 适用于每天一次给予人的单位剂型,其包含生理有效量的至少一种选自甾体雌激素,雌二醇,雌酮,甲羟孕酮,炔诺酮,炔诺酮,孕激素,甲炔炔酮和孕酮的激素, 至少一种类胡萝卜素,其中类胡萝卜素具有有效预防可能由激素给药引起的副作用的量。

    System and method for fast dynamic link adaptation
    8.
    发明申请
    System and method for fast dynamic link adaptation 有权
    快速动态链路适配的系统和方法

    公开(公告)号:US20050083897A1

    公开(公告)日:2005-04-21

    申请号:US11007955

    申请日:2004-12-09

    摘要: The present invention discloses a method and system for enabling efficient reduction of TFCs in the TFCS to achieve desired transmission, while remaining within desired power and data requirements. Upon the UE transmission power requirement exceeding the maximum or allowable transmission power the MAC shall be informed for subsequent TFC selection of all TFCs that currently exceed this limit. The UE will then chose the TFC with the next lower transmission power requirement and the sequence will continue until an acceptable TFC is determined. The present invention also enables the replacement of the TFCs in the TFCS and advanced determination of non-supported TFCs. The TFCs that require transmission power greater then the maximum or allowed UE transmission power shall be determined continuously in every TTI, not just in TTIs where the maximum power has been exceeded.

    摘要翻译: 本发明公开了一种能够有效地降低TFCS中的TFC以实现期望的传输并保持在期望的功率和数据要求内的方法和系统。 在UE发射功率要求超过最大或允许的发射功率时,MAC将被通知用于当前超过该限制的所有TFC的后续TFC选择。 然后,UE将选择具有下一个较低传输功率要求的TFC,并且该序列将继续,直到确定可接受的TFC为止。 本发明还能够更换TFCS中的TFC并且进一步确定不支持的TFC。 需要大于最大或允许的UE传输功率的传输功率的TFC应在每个TTI中连续地确定,而不仅仅是在超过最大功率的TTI中。

    Virtual beam system
    9.
    发明授权

    公开(公告)号:US5793798A

    公开(公告)日:1998-08-11

    申请号:US573946

    申请日:1995-12-18

    摘要: A virtual beam system operating in an environment, including a non-compatible receiver, includes a transmitting subsystem and a receiving subsystem. The transmitting subsystem includes an array of transmitting elements and an element position encoded composite signal generator for generating an element position encoded composite signal. The array of transmitting elements is operatively coupled to the signal generator. The transmitting subsystem radiates the element position encoded composite signal via the array of transmitting elements. The receiving subsystem is responsive to the element position encoded composite signal and includes a receiving element and an element position encoded composite signal decoder for decoding the element position encoded composite signal. The receiving element is operatively coupled to the signal decoder. The element position encoded composite signal appears to be radiated as a wide beam, with relatively low directive gain, when received and decoded by the non-compatible receiver. Conversely, the element position encoded composite signal appears to be radiated as a narrow beam, with relatively high directive gain, when received by the receiving element and decoded by the signal decoder of the receiving subsystem.