-
1.发明申请Photodynamic therapy in selective cell inactivation in blood and treating immune dysfunction diseases 失效光动力疗法在血液中选择性细胞灭活和治疗免疫功能障碍疾病公开(公告)号：US20050130952A1
公开(公告)日：2005-06-16
申请号：US11048452
申请日：2005-01-31
申请人： Julia Levy , Janice North
发明人： Julia Levy , Janice North
IPC分类号： C07D487/16 , A01N25/00 , A61B10/00 , A61K31/40 , A61K31/409 , A61K31/46 , A61K31/555 , A61K41/00 , A61K47/00 , A61M37/00 , A61P29/00 , A61P31/18 , A61P37/00 , A61P37/06 , C07D487/22 , F21V9/16 , G01N21/01
CPC分类号： A61K31/40 , A61K31/409 , A61K41/0071 , Y10S514/825 , Y10S514/885 , Y10S514/908
摘要： Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.
摘要翻译： 可以使用光动力疗法有效治疗多发性硬化和类风湿关节炎。 在该方案中，施用光敏化合物，允许分布在受影响的受试者中，然后照射受试者以活化光敏化合物。 或者，待处理对象的血液可以经受PDT体外。 在类风湿性关节炎的情况下，还可以使用关节处的局部治疗。
-
2.发明授权Method for inactivating pathogens in erythrocytes using photoactive compounds and plasma protein reduction 失效使用光活性化合物灭活红细胞病原体和降低血浆蛋白的方法
公开(公告)号：US5360734A
公开(公告)日：1994-11-01
申请号：US10469
申请日：1993-01-28
CPC分类号： A61L2/0011 , A01N1/0215 , A61K41/0071
摘要： The present invention provides a method for inactivating pathogens in a body fluid, such as plasma, red cells, platelets, leukocytes, and bone marrow. The present invention minimizes adverse effects caused by the photosensitive agents while retaining the disinfecting activity of such agents and processes. Pursuant to the present invention, prior to irradiating a body fluid including a photoactive drug, the extracellular fluid, which in the case of blood components includes plasma proteins is at least substantially reduced. Additionally, after the irradiation process, the resultant body fluid is prevented from contacting additional extracellular fluid, e.g., plasma proteins, for a predefined period.
摘要翻译： 本发明提供了灭活体液如血浆，红细胞，血小板，白细胞和骨髓中的病原体的方法。 本发明最小化由感光剂引起的不利影响，同时保持这些试剂和方法的消毒活性。 根据本发明，在照射包含光活性药物的体液之前，在血液成分包括血浆蛋白质的情况下的细胞外液体至少显着降低。 此外，在照射过程之后，防止所得体液接触另外的细胞外液，例如血浆蛋白，预定时间。
-
公开(公告)号：US6100290A
公开(公告)日：2000-08-08
申请号：US152993
申请日：1998-09-14
申请人： Julia G. Levy , Janice North
发明人： Julia G. Levy , Janice North
IPC分类号： C07D487/16 , A01N25/00 , A61B10/00 , A61K31/40 , A61K31/409 , A61K31/46 , A61K31/555 , A61K41/00 , A61K47/00 , A61M37/00 , A61P29/00 , A61P31/18 , A61P37/00 , A61P37/06 , C07D487/22 , F21V9/16 , G01N21/01
CPC分类号： A61K31/40 , A61K31/409 , A61K41/0071 , Y10S514/825 , Y10S514/885 , Y10S514/908
摘要： Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.
-
4.发明授权Photodynamic therapy in selective cell inactivation in blood and treating immune dysfunction diseases 失效光动力疗法在血液中选择性细胞灭活和治疗免疫功能障碍疾病公开(公告)号：US07479503B2
公开(公告)日：2009-01-20
申请号：US11048452
申请日：2005-01-31
申请人： Simon Leong , Agnes How-Ching Chan , David William Carey Hunt , Julia G. Levy , Martin Renke , Janice North
发明人： Simon Leong , Agnes How-Ching Chan , David William Carey Hunt , Julia G. Levy , Martin Renke , Janice North
CPC分类号： A61K31/40 , A61K31/409 , A61K41/0071 , Y10S514/825 , Y10S514/885 , Y10S514/908
摘要： Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.
摘要翻译： 可以使用光动力疗法有效治疗多发性硬化和类风湿关节炎。 在该方案中，施用光敏化合物，允许分布在受影响的受试者中，然后照射受试者以活化光敏化合物。 或者，待处理对象的血液可以经受PDT体外。 在类风湿性关节炎的情况下，还可以使用关节处的局部治疗。
-
公开(公告)号：US07015240B2
公开(公告)日：2006-03-21
申请号：US10622310
申请日：2003-07-17
申请人： Janice North , Peter Hnik , H. Andrew Strong
发明人： Janice North , Peter Hnik , H. Andrew Strong
IPC分类号： A61K31/40
CPC分类号： A61K31/409 , A61K41/0071
摘要： The invention relates to the use of photodynamic therapy (PDT) to treat macular edemas, including DME, CRVO and BRVO. It provides an alternative to photocoagulation and the disadvantages associated therewith.
-
公开(公告)号：US5776966A
公开(公告)日：1998-07-07
申请号：US889707
申请日：1992-05-27
申请人： Janice North
发明人： Janice North
IPC分类号： C07D487/16 , A01N25/00 , A61B10/00 , A61K31/40 , A61K31/409 , A61K31/555 , A61K41/00 , A61M37/00 , A61P31/18 , A61P37/06 , F21V9/16 , G01N21/01
CPC分类号： A61K31/40 , A61K31/409 , A61K41/0071 , Y10S514/885 , Y10S514/908
摘要： Treatment with a set of porphyrin compounds using a photodynamic therapy approach is able selectively to lower elevated levels of activated leukocytes in a leukocyte population. This is particularly helpful in subjects containing such elevated levels of T-cell subsets, such as HIV-infected subjects.
摘要翻译： 使用光动力学治疗方法用一组卟啉化合物治疗能够选择性降低白细胞群体中活化白细胞的升高水平。 这对于含有这种升高水平的T细胞亚群的受试者尤其有帮助，例如HIV感染的受试者。
-
公开(公告)号：US06849058B1
公开(公告)日：2005-02-01
申请号：US09583392
申请日：2000-05-31
申请人： Julia G. Levy , Janice North
发明人： Julia G. Levy , Janice North
IPC分类号： C07D487/16 , A01N25/00 , A61B10/00 , A61K31/40 , A61K31/409 , A61K31/46 , A61K31/555 , A61K41/00 , A61K47/00 , A61M37/00 , A61P29/00 , A61P31/18 , A61P37/00 , A61P37/06 , C07D487/22 , F21V9/16 , G01N21/01
CPC分类号： A61K31/40 , A61K31/409 , A61K41/0071 , Y10S514/825 , Y10S514/885 , Y10S514/908
摘要： Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.
-
公开(公告)号：US06599891B2
公开(公告)日：2003-07-29
申请号：US10199662
申请日：2002-07-19
申请人： Janice North , Peter Hnik , H. Andrew Strong
发明人： Janice North , Peter Hnik , H. Andrew Strong
IPC分类号： A61K3133
CPC分类号： A61K31/409 , A61K41/0071
摘要： The invention relates to the use of photodynamic therapy (PDT) to treat macular edemas, including DME, CRVO and BRVO. It provides an alternative to photocoagulation and the disadvantages associated therewith.
摘要翻译： 本发明涉及光动力疗法（PDT）用于治疗黄斑水肿，包括DME，CRVO和BRVO。 它提供了光凝的替代方案和与之相关的缺点。
-
9.发明授权Method for inactivating pathogens in compositions containing cells and plasma using photoactive compounds and plasma protein reduction 失效使用光敏化合物和血浆蛋白质还原来灭活含有细胞和血浆的组合物中病原体的方法
公开(公告)号：US5597722A
公开(公告)日：1997-01-28
申请号：US274507
申请日：1994-07-13
CPC分类号： A61L2/0011 , A01N1/0215 , A01N1/0294
摘要： The present invention provides a method for inactivating pathogens in a body fluid, such as plasma, red cells, platelets, leukocytes, and bone marrow. The present invention minimizes adverse effects caused by the photosensitive agents while retaining the disinfecting activity of such agents and processes. Pursuant to the present invention, prior to irradiating a body fluid including a photoactive drug, the extracellular fluid, which in the case of blood components includes plasma proteins is at least substantially reduced. Additionally, after the irradiation process, the resultant body fluid is prevented from contacting additional extracellular fluid, e.g., plasma proteins, for a predefined period.
摘要翻译： 本发明提供了灭活体液如血浆，红细胞，血小板，白细胞和骨髓中的病原体的方法。 本发明最小化由感光剂引起的不利影响，同时保持这些试剂和方法的消毒活性。 根据本发明，在照射包含光活性药物的体液之前，在血液成分包括血浆蛋白质的情况下的细胞外液体至少显着降低。 此外，在照射过程之后，防止所得体液接触另外的细胞外液，例如血浆蛋白，预定时间。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.031 秒)
