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1.发明授权Implantable cardiac rhythm management system having multiple therapy modalities 有权具有多种治疗方式的植入式心律管理系统公开(公告)号：US07346393B2
公开(公告)日：2008-03-18
申请号：US10460975
申请日：2003-06-12
申请人： Julio Spinelli , Qingsheng Zhu , Bruce H. Kenknight , Yinghong Yu , Jiang Ding
发明人： Julio Spinelli , Qingsheng Zhu , Bruce H. Kenknight , Yinghong Yu , Jiang Ding
IPC分类号： A61N1/36
CPC分类号： A61N1/3627
摘要： A cardiac rhythm management system for providing a plurality of therapy modalities. For example, the system may include a cardiac resynchronization therapy module for providing cardiac resynchronization therapy and a pacemaker module for providing bradycardia therapy, as well as a selector module coupled to the cardiac resynchronization therapy module and the bradycardia module. The selector module may select an operating mode from among a plurality of operating modes including the cardiac resynchronization therapy module and the pacemaker module. Various manual and automatic methods may be used to select the operating mode. In addition, a reversion management system may be included to assist the cardiac rhythm management system to recover in case of a disruption to the system.
摘要翻译： 一种用于提供多种治疗方式的心律管理系统。 例如，该系统可以包括用于提供心脏再同步治疗的心脏再同步治疗模块和用于提供心动过缓治疗的起搏器模块，以及耦合到心脏再同步治疗模块和心动过缓模块的选择器模块。 选择器模块可以从包括心脏再同步治疗模块和起搏器模块的多个操作模式中选择操作模式。 可以使用各种手动和自动方法来选择操作模式。 此外，还可以包括回归管理系统以帮助心律管理系统在系统中断的情况下恢复。
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2.发明授权Implantable cardiac rhythm management system having multiple therapy modalities 有权具有多种治疗方式的植入式心律管理系统公开(公告)号：US08352027B2
公开(公告)日：2013-01-08
申请号：US12048144
申请日：2008-03-13
申请人： Julio Spinelli , Qingsheng Zhu , Bruce H. Kenknight , Yinghong Yu , Jiang Ding
发明人： Julio Spinelli , Qingsheng Zhu , Bruce H. Kenknight , Yinghong Yu , Jiang Ding
IPC分类号： A61N1/36
CPC分类号： A61N1/3627
摘要： A cardiac rhythm management system for providing a plurality of therapy modalities. For example, the system may include a cardiac resynchronization therapy module for providing cardiac resynchronization therapy and a pacemaker module for providing bradycardia therapy, as well as a selector module coupled to the cardiac resynchronization therapy module and the bradycardia module. The selector module may select an operating mode from among a plurality of operating modes including the cardiac resynchronization therapy module and the pacemaker module. Various manual and automatic methods may be used to select the operating mode. In addition, a reversion management system may be included to assist the cardiac rhythm management system to recover in case of a disruption to the system.
摘要翻译： 一种用于提供多种治疗方式的心律管理系统。 例如，该系统可以包括用于提供心脏再同步治疗的心脏再同步治疗模块和用于提供心动过缓治疗的起搏器模块，以及耦合到心脏再同步治疗模块和心动过缓模块的选择器模块。 选择器模块可以从包括心脏再同步治疗模块和起搏器模块的多个操作模式中选择操作模式。 可以使用各种手动和自动方法来选择操作模式。 此外，还可以包括回归管理系统以帮助心律管理系统在系统中断的情况下恢复。
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3.发明申请IMPLANTABLE CARDIAC RHYTHM MANAGEMENT SYSTEM HAVING MULTIPLE THERAPY MODALITIES 有权具有多种治疗方式的可持续心脏健康管理系统公开(公告)号：US20080221635A1
公开(公告)日：2008-09-11
申请号：US12048144
申请日：2008-03-13
IPC分类号： A61N1/365
CPC分类号： A61N1/3627
摘要： A cardiac rhythm management system for providing a plurality of therapy modalities. For example, the system may include a cardiac resynchronization therapy module for providing cardiac resynchronization therapy and a pacemaker module for providing bradycardia therapy, as well as a selector module coupled to the cardiac resynchronization therapy module and the bradycardia module. The selector module may select an operating mode from among a plurality of operating modes including the cardiac resynchronization therapy module and the pacemaker module. Various manual and automatic methods may be used to select the operating mode. In addition, a reversion management system may be included to assist the cardiac rhythm management system to recover in case of a disruption to the system.
摘要翻译： 一种用于提供多种治疗方式的心律管理系统。 例如，该系统可以包括用于提供心脏再同步治疗的心脏再同步治疗模块和用于提供心动过缓治疗的起搏器模块，以及耦合到心脏再同步治疗模块和心动过缓模块的选择器模块。 选择器模块可以从包括心脏再同步治疗模块和起搏器模块的多个操作模式中选择操作模式。 可以使用各种手动和自动方法来选择操作模式。 此外，还可以包括回归管理系统以帮助心律管理系统在系统中断的情况下恢复。
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公开(公告)号：US08002553B2
公开(公告)日：2011-08-23
申请号：US10642998
申请日：2003-08-18
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. Kenknight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. Kenknight , Douglas R. Daum , Kent Lee
IPC分类号： G09B23/28
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
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5.发明授权Evaluating a patient condition using autonomic balance information in implatable cardiac devices 有权使用植入式心脏装置中的自主平衡信息评估患者状况公开(公告)号：US07899519B2
公开(公告)日：2011-03-01
申请号：US11168614
申请日：2005-06-28
IPC分类号： A61B5/0402
CPC分类号： A61B5/0452 , A61B5/0205 , A61B5/4809 , A61B5/4812 , A61M16/024 , A61M2230/04 , A61M2230/10 , A61M2230/63 , A61M2230/65 , A61N1/3622 , A61N1/365
摘要： Systems and methods for evaluating a patient condition using autonomic balance information involve providing an implantable cardiac device that acquires a cardiac waveform from a patient. One or more characteristics associated with autonomic balance of the patient are detected and used to evaluate a patient condition, such as sleep onset, sleep stage, cardiac vulnerability over a predetermined duration, and sleep disordered breathing. Patient activity levels may be sensed and used to evaluate the patient's condition, such as for determining a level of systemic stress. Characteristics associated with the autonomic balance include calculating an LF/HF ratio waveform and/or determining one or more morphological features of the LF/HF ratio waveform. Coordination with a patient-external device may facilitate transmission of information about one or more of the cardiac waveform, the one or more characteristics associated with the autonomic balance, and a marked cardiac waveform.
摘要翻译： 使用自主平衡信息评估患者状况的系统和方法涉及提供从患者获取心脏波形的可植入心脏装置。 检测与患者的自主平衡相关联的一个或多个特征，并用于评估患者状况，例如睡眠发作，睡眠阶段，预定持续时间内的心脏易感性和睡眠呼吸紊乱。 可以感测患者活动水平并用于评估患者的状况，例如用于确定全身应激水平。 与自主平衡相关的特征包括计算LF / HF比率波形和/或确定LF / HF比波形的一个或多个形态特征。 与患者外部设备的协调可以促进关于心脏波形中的一个或多个的信息的传输，与自主平衡相关联的一个或多个特征以及标记的心脏波形。
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6.发明申请EVALUATING A PATIENT CONDITION USING AUTONOMIC BALANCE INFORMATION IN IMPLANTABLE CARDIAC DEVICES 审中-公开使用自动平衡信息评估可携带心脏器械的患者状况公开(公告)号：US20110137367A1
公开(公告)日：2011-06-09
申请号：US13027978
申请日：2011-02-15
IPC分类号： A61N1/365 , A61B5/0205
CPC分类号： A61B5/0452 , A61B5/0205 , A61B5/4809 , A61B5/4812 , A61M16/024 , A61M2230/04 , A61M2230/10 , A61M2230/63 , A61M2230/65 , A61N1/3622 , A61N1/365
摘要： Systems and methods for evaluating a patient condition using autonomic balance information involve providing an implantable cardiac device that acquires a cardiac waveform from a patient. One or more characteristics associated with autonomic balance of the patient are detected and used to evaluate a patient condition, such as sleep onset, sleep stage, cardiac vulnerability over a predetermined duration, and sleep disordered breathing. Patient activity levels may be sensed and used to evaluate the patient's condition, such as for determining a level of systemic stress. Characteristics associated with the autonomic balance include calculating an LF/HF ratio waveform and/or determining one or more morphological features of the LF/HF ratio waveform. Coordination with a patient-external device may facilitate transmission of information about one or more of the cardiac waveform, the one or more characteristics associated with the autonomic balance, and a marked cardiac waveform.
摘要翻译： 使用自主平衡信息评估患者状况的系统和方法涉及提供从患者获取心脏波形的可植入心脏装置。 检测与患者的自主平衡相关联的一个或多个特征，并用于评估患者状况，例如睡眠发作，睡眠阶段，预定持续时间内的心脏易感性和睡眠呼吸障碍。 可以感测患者活动水平并用于评估患者的状况，例如用于确定全身应激水平。 与自主平衡相关的特征包括计算LF / HF比率波形和/或确定LF / HF比波形的一个或多个形态特征。 与患者外部设备的协调可以促进关于心脏波形中的一个或多个的信息的传输，与自主平衡相关联的一个或多个特征以及标记的心脏波形。
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公开(公告)号：US07333853B2
公开(公告)日：2008-02-19
申请号：US10305548
申请日：2002-11-26
IPC分类号： A61N1/00
CPC分类号： A61N1/37211 , A61N1/37282
摘要： Methods and systems for providing an implantable medical device with a controlled diagnostic function adapted to convert from a monitoring mode to a therapeutic mode upon sensing an actionable cardiovascular event are disclosed. A preferred embodiment uses an interactive control module to selectively control a plurality of gated circuits that turn the sensing, therapeutic and communications functions of the device on and off to conserve battery power and extend the life of the device. Some embodiments of a system disclosed herein also can be configured as a component of an Advanced Patient Management System that helps better monitor, predict and manage chronic diseases.
摘要翻译： 公开了用于提供具有受控诊断功能的可植入医疗装置的方法和系统，其适于在感测到可行动的心血管事件时从监测模式转换为治疗模式。 优选实施例使用交互式控制模块来选择性地控制多个门控电路，其开启和关闭设备的感测，治疗和通信功能以节省电池电力并延长设备的使用寿命。 本文公开的系统的一些实施例还可以被配置为高级患者管理系统的组件，其有助于更好地监测，预测和管理慢性疾病。
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公开(公告)号：US5803928A
公开(公告)日：1998-09-08
申请号：US788647
申请日：1997-01-24
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/058 , A61N2001/0585
摘要： Intravenous cardiac leads having at least one electrode intended to be implanted within the coronary artery are disclosed. Also disclosed are structures and techniques for advancing such leads through the atrium and coronary sinus into the coronary veins overlaying the left ventricle.
摘要翻译： 公开了具有至少一个待植入冠状动脉的电极的静脉内心脏引线。 还公开了用于将这种引线通过心房和冠状窦推进到覆盖左心室的冠状静脉的结构和技术。
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公开(公告)号：US5314462A
公开(公告)日：1994-05-24
申请号：US888492
申请日：1992-05-27
CPC分类号： A61N1/0573
摘要： An implantable defibrillation electrode including a conductive distal end portion and a non-conductive proximal end portion is provided with at least a major portion of the length of the distal end portion having a preconfigured shape and being resiliently deformable into a generally straight condition. The distal end portion includes distal and proximal ends and at least one of those ends is hollow and has hook structure shiftably supported therein for movement longitudinally thereof from a retracted position at least substantially contained within the hollow end and an extended position at least substantially fully outwardly projected from the hollow end. Spring structure is provided for yieldingly biasing the hook structure from the extended position toward the retracted position and axial thrust developing structure is slidingly telescoped through the proximal end portion and operatively associated with the hook structure for exerting an axial thrust thereon from the terminal end of the proximal end portion in order to effect shifting of the hook structure from the retracted position to the extended position.
摘要翻译： 包括导电远端部分和非导电近端部分的可植入除颤电极设置有远端部分的长度的至少大部分具有预先配置的形状并且可弹性变形为大致直线的状态。 远端部分包括远端和近端，并且这些端部中的至少一个端部是中空的并且具有可移动地支撑在其中的钩结构，用于使其纵向移动，从至少基本上容纳在中空端部内的缩回位置和至少基本上完全向外的延伸位置 从中空端突出。 提供弹簧结构用于使挂钩结构从延伸位置朝向缩回位置有效地偏置，并且轴向推力显影结构通过近端部分滑动伸缩并与钩结构可操作地相关联，从而从其上端施加轴向推力 近端部分，以便实现钩结构从缩回位置到延伸位置的移动。
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10.发明授权System and method for correlating biometric trends with a related temporal event 有权将生物识别趋势与相关时间事件相关联的系统和方法公开(公告)号：US07378955B2
公开(公告)日：2008-05-27
申请号：US10335396
申请日：2003-01-03
CPC分类号： A61B5/0002 , G06F19/00 , G06Q50/22
摘要： Systems and methods for correlating biometric trends with a related temporal event are disclosed. A preferred embodiment utilizes an implantable medical device comprising at least one sensor in electronic communication with a patient management system adapted to temporally analyze and correlate biometric data. Some embodiments of a system disclosed herein also can be configured as an Advanced Patient Management system that helps better monitor, predict and manage chronic diseases.
摘要翻译： 公开了将生物识别趋势与相关时间事件相关联的系统和方法。 优选实施例利用可植入医疗装置，其包括至少一个传感器，该传感器与患者管理系统进行电子通信，患者管理系统适于暂时分析和关联生物特征数据。 本文公开的系统的一些实施例还可以被配置为有助于更好地监测，预测和管理慢性疾病的高级患者管理系统。
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