-
公开(公告)号：US20080108808A1
公开(公告)日：2008-05-08
申请号：US11929673
申请日：2007-10-30
申请人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathon Salsbury , Luckner Ulysse
发明人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathon Salsbury , Luckner Ulysse
IPC分类号： C07D401/04 , C07D401/14 , C07D403/04
CPC分类号： C07D403/04 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C═NR9; and each L, X, R1, R2, and R3 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含包含以下的化合物：其中M为N或CR 4; Q 1和Q 2各自独立地选自CO，SO，SO 2和C-NR 9 并且每个L，X，R 1，R 2和R 3 3如本文所定义。
-
公开(公告)号：US20080108807A1
公开(公告)日：2008-05-08
申请号：US11929482
申请日：2007-10-30
申请人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathon Salsbury , Luckner Ulysse
发明人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathon Salsbury , Luckner Ulysse
IPC分类号： C07D401/04 , C07D401/14 , C07D403/04
CPC分类号： C07D403/04 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C═NR9; and each L, X, R1, R2, and R3 are as defined herein.
-
公开(公告)号：US20050261271A1
公开(公告)日：2005-11-24
申请号：US11080992
申请日：2005-03-15
申请人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathon Salsbury , Luckner Ulysse
发明人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathon Salsbury , Luckner Ulysse
IPC分类号： C07D239/54 , A61K9/08 , A61K9/20 , A61K31/506 , A61K31/513 , A61K31/53 , A61K31/55 , A61P3/10 , A61P13/12 , A61P17/06 , A61P19/02 , A61P25/00 , A61P29/00 , A61P31/18 , A61P35/00 , A61P37/02 , A61P37/06 , A61P39/02 , A61P43/00 , C07D239/545 , C07D239/553 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D409/14 , C07D43/02
CPC分类号： C07D403/04 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C═NR9; and each L, X, R1, R2, and R3 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含包含以下的化合物：其中M为N或CR 4; Q 1和Q 2各自独立地选自CO，SO，SO 2和C-NR 9 并且每个L，X，R 1，R 2和R 3 3如本文所定义。
-
公开(公告)号：US20080003283A1
公开(公告)日：2008-01-03
申请号：US11835295
申请日：2007-08-07
申请人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathan Salsbury , Luckner Ulysse
发明人： Jun Feng , Stephen Gwaltney , Jeffrey Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathan Salsbury , Luckner Ulysse
IPC分类号： A61K31/506 , A61K9/20 , A61P13/12 , A61P19/00 , A61P3/10 , A61P35/00 , A61P37/00 , C07D239/08 , C12N9/99
CPC分类号： C07D403/04 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Compounds are provided for use with DPP-IV of the formula: Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译： 化合物被提供用于下式的DPP-IV：还提供包含这些化合物的药物组合物，试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
-
公开(公告)号：US07795428B2
公开(公告)日：2010-09-14
申请号：US11835295
申请日：2007-08-07
申请人： Jun Feng , Stephen L. Gwaltney , Jeffrey Alan Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathan S. Salsbury , Luckner Ulysse
发明人： Jun Feng , Stephen L. Gwaltney , Jeffrey Alan Stafford , Zhiyuan Zhang , Bruce Elder , Paul Isbester , Grant Palmer , Jonathan S. Salsbury , Luckner Ulysse
IPC分类号： C07D401/04 , A61K31/506 , A61P3/10 , A61P19/02 , A61P35/00
CPC分类号： C07D403/04 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Compounds are provided for use with DPP-IV of the formula: Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
摘要翻译： 化合物被提供用于下式的DPP-IV：还提供包含这些化合物的药物组合物，试剂盒和制品; 用于制备化合物的方法和中间体; 以及使用所述化合物的方法。
-
公开(公告)号：US08222411B2
公开(公告)日：2012-07-17
申请号：US12066769
申请日：2006-09-15
申请人： Jun Feng , Stephen L. Gwaltney , Jeffrey A. Stafford , Zhiyuan Zhang , Paul R. Brodfuahrer , Bruce Elder , Paul Isbester , Richard S. Fornicola , Philip B. Kisanga , Bingidimi I. Mobele , Grant J. Palmer , Maxwell M. Reeve , Jonathon S. Salsbury , Luckner Ulysse , Sripathy Venkatraman
发明人： Jun Feng , Stephen L. Gwaltney , Jeffrey A. Stafford , Zhiyuan Zhang , Paul R. Brodfuahrer , Bruce Elder , Paul Isbester , Richard S. Fornicola , Philip B. Kisanga , Bingidimi I. Mobele , Grant J. Palmer , Maxwell M. Reeve , Jonathon S. Salsbury , Luckner Ulysse , Sripathy Venkatraman
IPC分类号： C07D239/02
CPC分类号： C07D239/553 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Methods of making compounds of the formula (I) wherein the variables are as defined herein. Also, methods of making compounds that may be used to inhibit dipeptidyl peptidase.
摘要翻译： 制备式（I）化合物的方法，其中变量如本文所定义。 另外，制备可用于抑制二肽基肽酶的化合物的方法。
-
公开(公告)号：US20090275750A1
公开(公告)日：2009-11-05
申请号：US12066769
申请日：2006-09-15
申请人： Jun Feng , Stephen L. Gwaltney , Jeffrey A. Stafford , Zhiyuan Zhang , Paul R. Brodluahrer , Bruce Elder , Paul Isbester , Richard S. Fornicola , Philip B. Kisanga , Bingidimi I. Mobele , Grant J. Palmer , Maxwell M. Reeve , Jonathon S. Salsbury , Luckner Ulysse , Sripathy Venkatraman
发明人： Jun Feng , Stephen L. Gwaltney , Jeffrey A. Stafford , Zhiyuan Zhang , Paul R. Brodluahrer , Bruce Elder , Paul Isbester , Richard S. Fornicola , Philip B. Kisanga , Bingidimi I. Mobele , Grant J. Palmer , Maxwell M. Reeve , Jonathon S. Salsbury , Luckner Ulysse , Sripathy Venkatraman
IPC分类号： C07D403/04 , C07D401/04
CPC分类号： C07D239/553 , C07D239/545 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/14
摘要： Methods of making compounds of the formula (I) wherein the variables are as defined herein. Also, methods of making compounds that may be used to inhibit dipeptidyl peptidase.
摘要翻译： 制备式（I）化合物的方法，其中变量如本文所定义。 另外，制备可用于抑制二肽基肽酶的化合物的方法。
-
公开(公告)号：US20050070531A1
公开(公告)日：2005-03-31
申请号：US10918186
申请日：2004-08-12
申请人： Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Zhiyuan Zhang
IPC分类号： A61K9/08 , A61K9/20 , A61K31/506 , A61P3/10 , A61P7/00 , A61P13/12 , A61P17/06 , A61P19/00 , A61P19/02 , A61P25/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P37/00 , A61P37/06 , A61P43/00 , C07D239/02 , C07D239/36 , C07D239/46 , C07D239/52 , C07D285/16 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04 , A61K31/549 , A61K31/513
CPC分类号： C07D239/36 , C07D239/47 , C07D239/52 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
-
公开(公告)号：US20050065148A1
公开(公告)日：2005-03-24
申请号：US10918318
申请日：2004-08-12
申请人： Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Zhiyuan Zhang
IPC分类号： A61K9/08 , A61K9/20 , A61K31/506 , A61P3/10 , A61P7/00 , A61P13/12 , A61P17/06 , A61P19/00 , A61P19/02 , A61P25/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P37/00 , A61P37/06 , A61P43/00 , C07D239/02 , C07D239/36 , C07D239/46 , C07D239/52 , C07D285/16 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04 , C07D273/04 , A61K31/539
CPC分类号： C07D239/36 , C07D239/47 , C07D239/52 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
-
公开(公告)号：US20050004117A1
公开(公告)日：2005-01-06
申请号：US10809635
申请日：2004-03-24
申请人： Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Zhiyuan Zhang
IPC分类号： A61K20060101 , A61K6/00 , A61K31/513 , A61K31/517 , A61K31/519 , A61K31/5395 , A61K31/549 , C07D239/95 , C07D285/16 , C07D401/04 , C07D403/04 , C07D417/02 , C07D471/04 , C07D473/18 , C07D487/04
CPC分类号： C07D471/04 , C07D401/04 , C07D403/04 , C07D473/18 , C07D487/04
摘要： Compounds, pharmaceuticals, kits, and methods are provided for use with DPP-IV and other S9 protease that comprise a compound comprising the formula: wherein Q is selected from the group of CO, SO, SO2, or C═NR9; and R1, R2, R3 and R4 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含下式的化合物：其中Q选自CO，SO，SO 2或C = NR 9; 并且R 1，R 2，R 3和R 4如本文所定义。
-
-
-
-
-
-
-
-
-
搜索结果
63 条记录 (耗时 0.047 秒)
