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    ADSORBENT
    1.
    发明申请
    ADSORBENT 审中-公开
    吸引力

    公开(公告)号：US20150297820A1

    公开(公告)日：2015-10-22

    申请号：US14427247

    申请日：2013-09-09

    Applicant: KANEKA CORPORATION

    Inventor： Yoshikazu KAWAI ,  Ken-ichiro MORIO ,  Fuminori KONIKE ,  Kana WATANABE ,  Yasuyuki SUZUKI ,  Masaru HIRANO

    IPC: A61M1/36 ,  C08L1/02

    CPC classification number: A61M1/3679 ,  A61K9/1652 ,  C08B15/10 ,  C08B16/00 ,  C08J3/126 ,  C08J3/16 ,  C08J2301/02 ,  C08J2405/02 ,  C08J2489/00 ,  C08L1/02 ,  C08L5/02 ,  C08L89/00

    Abstract: The objective of the present invention is to obtain an adsorbent having high adsorption capacity and high strength comprising porous cellulose beads obtained without using an auxiliary material which is highly toxic and corrosive and without a cumbersome and industrially adverse step. The present invention is characterized by immobilizing a ligand onto porous cellulose beads obtained by mixing a cold alkaline aqueous solution and cellulose powder as a raw material to prepare a cellulose dispersion and bringing the cellulose dispersion into contact with a coagulating solvent.

    Abstract translation: 本发明的目的是获得具有高吸附能力和高强度的吸附剂，其包含多孔纤维素珠粒，而不使用高毒性和腐蚀性的辅助材料，并且没有麻烦和工业上不利的步骤。 本发明的特征在于将配体固定在通过混合冷碱水溶液和纤维素粉末作为原料而获得的多孔纤维素珠粒上，以制备纤维素分散体并使纤维素分散体与凝固溶剂接触。

    METHOD OF PRODUCING PEPTIDE
    2.
    发明申请
    METHOD OF PRODUCING PEPTIDE 审中-公开
    生产肽的方法

    公开(公告)号：US20140288268A1

    公开(公告)日：2014-09-25

    申请号：US14204074

    申请日：2014-03-11

    Applicant: KANEKA CORPORATION

    Inventor： Hiroshi MURAO ,  Ken-ichiro MORIO ,  Masaru MITSUDA

    IPC: C07K1/06 ,  C07K1/14

    CPC classification number: C07K1/061 ,  C07K1/02 ,  C07K1/14 ,  C07K5/06078 ,  C07K5/06095 ,  C07K5/0806 ,  C07K5/0808 ,  C07K5/101

    Abstract: The present invention is related to a method of producing a peptide, characterized in contacting a reaction mixture with a base after a condensation reaction to hydrolyze while a basic condition is maintained until a ratio of a remaining unreacted active ester of an acid component is decreased to 1% or less in a liquid phase peptide synthesis method. According to the invention, a target peptide of high purity can be simply and efficiently produced by a continuous liquid phase synthesis method. Further, the present invention is related to a method of producing a peptide, characterized in using an amide-type solvent immiscible with water in a liquid phase peptide synthesis method. According to the invention, various peptides can be produced by the liquid phase synthesis method without being restricted by the amino acid sequence of the target peptide.

    Abstract translation: 本发明涉及一种生产肽的方法，其特征在于在缩合反应之后将反应混合物与碱反应以在碱性条件保持下进行水解，直到酸组分的剩余未反应的活性酯的比例降低至 在液相肽合成方法中为1％以下。 根据本发明，可以通过连续液相合成法简单有效地制备高纯度的靶肽。 此外，本发明涉及一种制备肽的方法，其特征在于在液相肽合成方法中使用与水不混溶的酰胺型溶剂。 根据本发明，可以通过液相合成法制备各种肽，而不受目标肽的氨基酸序列的限制。

    METHOD FOR PRODUCING POROUS CELLULOSE BEADS AND ADSORBENT EMPLOYING SAME
    4.
    发明申请
    METHOD FOR PRODUCING POROUS CELLULOSE BEADS AND ADSORBENT EMPLOYING SAME 审中-公开
    生产多孔纤维素珠的方法和使用它的吸附剂

    公开(公告)号：US20160243521A1

    公开(公告)日：2016-08-25

    申请号：US15029551

    申请日：2014-10-14

    Applicant: KANEKA CORPORATION

    Inventor： Asuka HAYASHI ,  Yoshikazu KAWAI ,  Ken-ichiro MORIO

    IPC: B01J20/24 ,  B01J20/30 ,  C07K17/12 ,  C08J9/28 ,  C07K1/22 ,  B01J20/285 ,  C08J9/16

    CPC classification number: B01J20/24 ,  B01J20/285 ,  B01J20/286 ,  B01J20/305 ,  B01J20/3085 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3274 ,  B01J20/3293 ,  C07K1/145 ,  C07K1/22 ,  C07K17/12 ,  C08B15/10 ,  C08J9/16 ,  C08J9/28 ,  C08J2201/026 ,  C08J2201/0547 ,  C08J2301/00

    Abstract: The objective of the present invention is to provide a method for easily and efficiently producing cellulose beads which have pore shape suitable for an adsorbent and of which adsorption performance is excellent without using highly toxic and highly corrosive auxiliary raw material and without industrially disadvantageous cumbersome step. The method for producing porous cellulose beads according to the present invention is characterized in comprising (a) the step of preparing a fine cellulose dispersion by mixing a low temperature alkaline aqueous solution and cellulose, (b) the step of preparing a mixed liquid by adding a crosslinking agent to the fine cellulose dispersion, (c) the step of preparing an emulsion by dispersing the mixed liquid in a dispersion medium, (d) the step of contacting the emulsion with a coagulating solvent.

    Abstract translation: 本发明的目的是提供一种容易且有效地制造具有适合于吸附剂的孔隙形状的纤维素珠粒的方法，其吸附性能优异，而不需要使用高毒性和高腐蚀性的辅助原料，而且在工业上不利的繁琐步骤。 根据本发明的多孔纤维素珠粒的制造方法的特征在于，（a）通过混合低温碱性水溶液和纤维素来制备细纤维素分散液的步骤，（b）通过添加制备混合液体的步骤 （c）通过将混合液体分散在分散介质中制备乳液的步骤，（d）使乳液与凝固溶剂接触的步骤。

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