公开(公告)号：US20240226403A1

公开(公告)日：2024-07-11

申请号：US18561569

申请日：2022-04-12

Applicant: KANEKA CORPORATION ,  Broad Bean Science Co., LTD.

Inventor： Yuta FUJITA ,  Makoto KUROO

IPC: A61M1/36 ,  A61K35/14 ,  A61P7/08

CPC classification number: A61M1/3633 ,  A61K35/14 ,  A61P7/08 ,  A61M2202/0413

Abstract: The objective of the present invention is to provide a treatment material for the treatment of a disease of which symptom is alleviated or treated by reducing a blood phosphorus concentration. The treatment material according to the present invention is characterized in comprising a water-insoluble carrier and 1 or more adsorbing groups selected from the group consisting of a phosphate group, a phosphonate group, a phosphinate group, an amino group, a carboxy group and a thiol group, wherein the adsorbing group binds to the water-insoluble carrier through a linker group, the treatment material is used for treating a disease, wherein a symptom of the disease is alleviated or treated by reducing a blood phosphorus concentration, and dialyzed blood is passed through the treatment material to adsorb a calciprotein particle in the dialyzed blood on the adsorbing group, or blood is passed through the treatment material and then dialyzed.

公开(公告)号：US20240139394A1

公开(公告)日：2024-05-02

申请号：US18407992

申请日：2024-01-09

Applicant: KANEKA CORPORATION ,  BROAD BEAN SCIENCE CO., LTD.

Inventor： Ai YONEZAWA ,  Kana WATANABE ,  Makoto KUROO

IPC: A61M1/34 ,  A61M1/36 ,  B01D15/00 ,  B01J20/24 ,  B01J20/32 ,  C07K1/14

CPC classification number: A61M1/3496 ,  A61M1/3687 ,  B01D15/00 ,  B01J20/24 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3265 ,  B01J20/3293 ,  C07K1/14

Abstract: The purpose of the present invention is to adsorb calciprotein particles. An adsorbent for calciprotein particles of the present invention is characterized in that the surface of a water-insoluble carrier is covalently bonded, through a hydrocarbon group, to at least one selected from the group consisting of amino group, carboxyl group, phosphate group, phosphono group, phosphino group, and thiol group.

公开(公告)号：US20200238253A1

公开(公告)日：2020-07-30

申请号：US16322686

申请日：2017-07-31

Applicant: KANEKA CORPORATION ,  JICHI MEDICAL UNIVERSITY

Inventor： Ai YONEZAWA ,  Kana WATANABE ,  Makoto KUROO

IPC: B01J20/24 ,  C07K1/14 ,  B01J20/32 ,  A61M1/36 ,  A61M1/34 ,  B01D15/00

Abstract: The purpose of the present invention is to adsorb calciprotein particles. An adsorbent for calciprotein particles of the present invention is characterized in that the surface of a water-insoluble carrier is covalently bonded, through a hydrocarbon group, to at least one selected from the group consisting of amino group, carboxyl group, phosphate group, phosphono group, phosphino group, and thiol group.