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公开(公告)号:US20150247008A1
公开(公告)日:2015-09-03
申请号:US14713256
申请日:2015-05-15
发明人: HOLGER GRUELL , ANKE DE VRIES , SANDER LANGEREIS , JOHAN LUB , ERICA MARIA GERARDA AUSSEMS-CUSTERS
IPC分类号: C08G81/02 , A61K49/12 , A61K9/107 , A61K51/12 , A61K51/06 , A61K9/127 , A61K49/18 , A61K49/04
CPC分类号: C08G81/025 , A61K9/107 , A61K9/1075 , A61K9/1273 , A61K9/5146 , A61K49/0414 , A61K49/126 , A61K49/1806 , A61K49/1812 , A61K49/1818 , A61K51/06 , A61K51/065 , A61K51/1217 , A61K51/1237 , A61K51/1251
摘要: Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T1/T2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.
摘要翻译: 描述的是具有螯合部分的两亲性聚合物。 两亲聚合物是包含亲水嵌段和疏水嵌段的嵌段共聚物,螯合部分连接到亲水嵌段的端基。 所公开的聚合物能够自组装成结构如胶束和聚合物囊泡。 以与螯合部分配位络合物形式存在的合适金属,本发明的螯合两亲性聚合物适用于需要金属标记的各种成像技术,例如MRI(T1 / T2加权造影剂或CEST造影剂)SPECT ,PET或光谱CT。
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公开(公告)号:US20180235341A1
公开(公告)日:2018-08-23
申请号:US15746187
申请日:2016-11-03
发明人: WOUTER HENDRIK CORNELIS SPOORENDONK , JONATHAN ALAMBRA PALERO , BABU VARGHESE , TIM TIELEMANS , JOHAN LUB , MARCO BARAGONA
摘要: A hair care device for enhancing uptake of a topical in hair. The hair care device comprises a topical delivery unit for applying the topical to the hair surface, an ultrasound generator (103) for generating ultrasound at a frequency exceeding 15 MHz, wherein an ultrasound intensity is in a range between 2 W/cm2 and 100 W/cm2, and an ultrasound transducer (105) for applying ultrasound to the topical and/or the hair surface to enhance uptake of the topical by the hair.
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公开(公告)号:US20210204667A1
公开(公告)日:2021-07-08
申请号:US15999589
申请日:2017-02-16
发明人: TIM TIELEMANS , MARCO BARAGONA , BABU VARGHESE , JONATHAN ALAMBRA PALERO , WOUTER HENDRIK CORNELIS SPOORENDONK , JOHAN LUB
摘要: An ultrasound hair care device (10) for drying and styling hair (20). An ultrasound unit (12-18) applies ultrasound to the hair (20). A hair moisture measurement unit (22) measures a moisture level of the hair (20). A control unit (24) controls the ultrasound unit (12-18) based on the moisture level. In accordance with the present invention, in dependence on the moisture level, ultrasound is applied to the hair (20) at a first frequency not exceeding 1 MHz for drying the hair (20), and/or at a second frequency of at least 1 MHz for styling the hair (20).
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公开(公告)号:US20190218458A1
公开(公告)日:2019-07-18
申请号:US16332854
申请日:2017-09-18
发明人: JOHAN LUB , NICOLAAS PETRUS WILLARD , CORNELIS PETRUS HENDRIKS , KAREL JOHANNES ADRIANUS VAN DEN AKER
CPC分类号: C09K19/3852 , B29C70/00 , B32B7/023 , B32B27/08 , B32B2307/40 , C09K19/2007 , C09K19/24 , C09K19/3804 , C09K19/3833 , C09K19/542 , C09K2019/0425 , C09K2019/0437 , C09K2019/0448 , C09K2019/2035 , C09K2019/2078 , C09K2019/3425 , C09K2219/00 , F03G7/005 , F03G7/06 , H02N11/006
摘要: An actuator device comprises a stack formed from a plurality of photoresponsive layers, which deform in response to light, which are partitioned by respective deformable non-photoresponsive layers. The deformable non-photoresponsive layers guide light between and to the photoresponsive layers, and can follow the deformation of the photoresponsive layers.
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公开(公告)号:US20160296427A1
公开(公告)日:2016-10-13
申请号:US15035619
申请日:2014-11-14
发明人: NIGEL DAVID YOUNG , JAMES DONALD GWYER , HERMANN CHRISTIAN RECCIUS , ZEYNEP SABAH , VEENA MOHAN , ESTELLE JULIE DOROTHEE BERNARD-FICHET , ANTONIUS WILHELMUS MARIA DE LAAT , JOHAN LUB , NICOLAAS PETRUS WILLARD
IPC分类号: A61K8/04 , A61K8/02 , A61K8/22 , A61K8/65 , A61K8/81 , A61K8/31 , A61K8/64 , A61Q11/00 , A61K8/34
CPC分类号: A61K8/044 , A61K8/0233 , A61K8/22 , A61K8/31 , A61K8/34 , A61K8/37 , A61K8/42 , A61K8/64 , A61K8/65 , A61K8/8152 , A61K2800/884 , A61Q11/00
摘要: A system for providing an oral care agent includes a first layer containing the oral care agent and a second layer. The first layer can be applied directly to teeth. The second layer can subsequently be applied onto the first layer to inhibit leakage of the oral care agent outwards into the mouth.
摘要翻译: 用于提供口腔护理剂的系统包括含有口腔护理剂的第一层和第二层。 第一层可以直接应用于牙齿。 随后可以将第二层施加到第一层上,以防止口腔护理剂向口外泄漏。
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公开(公告)号:US20180310685A1
公开(公告)日:2018-11-01
申请号:US15768583
申请日:2016-11-07
发明人: BABU VARGHESE , MARCO BARAGONA , JONATHAN ALAMBRA PALERO , JOHAN LUB , WOUTER HENDRIK CORNELIS SPOORENDONK , TIM TIELEMANS
IPC分类号: A45D1/04
CPC分类号: A45D1/04 , A45D1/06 , A45D1/28 , A45D2200/205
摘要: A hair care device (100) comprises a heat source (103) for heating hair up till a first temperature that is no more than 150° C. (and thus lower than a critical temperature at which hair cuticle damage will occur), and a radiation source (102) for—in combination with heat from the heat source (103)—selectively heating a hair cortex to a second temperature exceeding the first temperature and sufficiently high for hair styling.
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