公开(公告)号：US12150744B2

公开(公告)日：2024-11-26

申请号：US16651568

申请日：2018-09-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Shaoxiong Sun ,  Wouter Herman Peeters ,  Rick Bezemer ,  Xi Long ,  Ronaldus Maria Aarts

IPC: A61B5/026 ,  A61B5/00 ,  A61B5/024 ,  A61B5/029 ,  A61B5/0295 ,  A61B5/1455

Abstract: In a sensor system (12), output signals of at least one PPG sensor (14) are processed to derive a modified pulse amplitude variation (PAV) value, being modified to take account of a baseline variation of the PPG sensor output signal. In particular, the modified PAV is derived through performing a modification step (42) in which either: a baseline variation of the PPG sensor output is derived and combined with a previously derived PAV, or, a PPG sensor output is first processed to perform baseline variation compensation, in advance of then deriving a PAV from the compensated signal.

公开(公告)号：US11769579B2

公开(公告)日：2023-09-26

申请号：US16471150

申请日：2017-12-20

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Joachim Kahlert ,  Calina Ciuhu ,  Maarten Petrus Joseph Kuenen ,  Rick Bezemer ,  Laurentia Johanna Huijbregts

IPC: G16H20/30 ,  A61M16/00 ,  A61B5/00 ,  A61B5/0295

CPC classification number: G16H20/30 ,  A61B5/0082 ,  A61B5/0295 ,  A61M16/024 ,  A61M16/0003

Abstract: The present disclosure pertains to a system and method for monitoring and for facilitating pulmonary and systemic hemodynamics in the treatment and/or prevention of cardiac arrhythmias or structural cardiac changes, caused by altered preload. The system comprises: a pressure generator; a first sensor configured to generate output signals conveying information related to venous blood accumulation during cardiac preload in the subject; a second sensor configured to generate output signals conveying information related to systemic arterial circulation in the subject; and one or more hardware processors configured by machine-readable instructions to control the pressure generator to adjust the pressure levels of the flow of breathable gas during one or both of inhalation and exhalation to facilitate the pulmonary and systemic circulation based on the output signals from the first sensor and the second sensor.

公开(公告)号：US10687729B2

公开(公告)日：2020-06-23

申请号：US14935727

申请日：2015-11-09

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria Kahlman ,  Rick Bezemer

IPC: A61B5/05 ,  A61B5/00 ,  A61B90/98 ,  A61B5/0265 ,  A61B5/053 ,  A61B5/024

Abstract: There is provided a measurement apparatus for estimating a value of a physiological characteristic of a subject. The apparatus comprises a radio-frequency (RF) power generating apparatus, a detector, and a controller in communication with the RF power generating apparatus. The RF power generating apparatus comprises a transmit antenna for emitting RF radiation; an RF signal generator; and a transmission line connecting the RF signal generator to the transmit antenna. The detector is arranged to measure the variation of at least one parameter correlated with attenuation of the emitted RF radiation, during the measurement period. The controller is arranged to: cause the RF power generating apparatus to emit RF radiation during a measurement period; receive measurements of the variation of the at least one parameter from the detector; and calculate a value of a physiological characteristic of a subject based on the received measurements.

公开(公告)号：US12076190B2

公开(公告)日：2024-09-03

申请号：US17298040

申请日：2019-12-03

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Shriram Sethuraman ,  Sergei Y. Shulepov ,  Sabina Manzari ,  Nico Maris Adriaan De Wild ,  Krishnamoorthy Palanisamy ,  Denny Mathew ,  Rick Bezemer

IPC: A61B8/00 ,  A61B8/08

CPC classification number: A61B8/483 ,  A61B8/0891 ,  A61B8/4488 ,  A61B8/4494 ,  A61B8/461 ,  A61B8/488 ,  A61B8/5207

Abstract: The invention provides a method for guiding the acquisition of ultrasound data. The method begins by obtaining ultrasound data from a plurality of data acquisition planes and performing spatial registration of the data acquisition planes. A number of vessels are then identified in each data acquisition plane. A location of a vessel bifurcation is then identified based on the spatial registration of the data acquisition planes and the number of vessels in each data acquisition plane. A guidance instruction is generated based on the location of the vessel bifurcation, wherein the guidance instruction is adapted to indicate a location to obtain further ultrasound data.

公开(公告)号：US11350859B2

公开(公告)日：2022-06-07

申请号：US16470636

申请日：2017-12-20

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Maarten Petrus Joseph Kuenen ,  Rick Bezemer ,  Laurentia Johanna Huijbregts ,  Joachim Kahlert

IPC: A61B5/1455 ,  A61M16/00 ,  A61B5/00

Abstract: Presented are concepts for monitoring cardio-respiratory function of a patient. One such concept employs an optical sensor unit (10) for sensing light from tissue of the patient in response to temporary airway pressure changes provided via a respiratory support unit (50). By sensing variations in blood volume in the central site vein in response to temporary airway pressure changes, venous information of the person may be obtained.

公开(公告)号：US10582885B2

公开(公告)日：2020-03-10

申请号：US15312841

申请日：2015-05-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Rick Bezemer

IPC: A61B5/145 ,  A61B5/0295 ,  A61B5/1455 ,  A61B5/00

Abstract: The present invention relates to a device and method for noninvasively determining the hematocrit value of a subject. The device comprises a light source (22, 23) for emitting light onto a skin area of the subject, said light comprising first light at a first wavelength in a first wavelength range between 500 and 1000 nm and second light at a second wavelength in a second wavelength range between 1000 and 2000 nm, a reflection detector (24) for detecting light reflected from said skin area of the subject in response to light illumination by said light source, a transmission detector (25) for detecting light transmitted through said skin area of the subject in response to light illumination by said light source, a processing unit (31) for deriving plethysmography, PPG, signals for said first and second wavelengths from the light detected by said reflection detector (24) and said transmission detector (25), and an analysis unit (32) for determining the hematocrit value of the subject from said PPG signals.

公开(公告)号：US10231667B2

公开(公告)日：2019-03-19

申请号：US14923007

申请日：2015-10-26

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Denny Mathew ,  Kiran Hamilton J. Dellimore ,  Rick Bezemer

IPC: A61B5/00 ,  A61B5/024 ,  A61B5/0205 ,  A61B5/01 ,  A61B5/08 ,  A61B5/053 ,  A61B5/087 ,  A61B5/1455

Abstract: The present invention relates to a device (10) and method for non-invasively measuring a hydration state of a living being (62). To improve with respect to the convenience-to-use, the cost-effectiveness and the accuracy of the delivered results, the proposed device comprises a first light source (14) for emitting light of a first wavelength into a tissue portion (12) of the living being (62), polarization means (18) for polarizing at least part of the emitted light prior to an interaction of the emitted light with the tissue portion (12), a first light detector (26) for detecting polarized light of the first wavelength reflected at the tissue portion (12) and processing means (32) configured to derive a tissue hydration parameter from the detected reflected polarized light and to determine a body hydration index based on said tissue hydration parameter.

公开(公告)号：US20180125444A1

公开(公告)日：2018-05-10

申请号：US15566926

申请日：2016-04-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria Kahlman ,  Jan Valentin Wendelin Sebastian Werth ,  Rick Bezemer

IPC: A61B7/00 ,  A61B5/00 ,  A61B5/113

CPC classification number: A61B7/003 ,  A61B5/0205 ,  A61B5/08 ,  A61B5/1135 ,  A61B5/4842 ,  A61B5/6831 ,  A61B5/6833

Abstract: The present invention relates to device, system and method for detecting a cardiac and/or respiratory disease of a subject. The proposed device comprises a sound input (20) for obtaining a sound signal representing sounds generated by the subject's body; a motion input (21) for obtaining a motion signal representing motions generated by the subject's body; and a processor (22) for processing the obtained sound signal and motion signal. This processing includes identifying inhalation and/or exhalation periods of the subject based on the motion signal, detecting abnormal lung sounds during inhalation and/or exhalation periods based on the sound signal, determining abnormal lung sound characteristics of the detected abnormal lung sounds, determining breathing characteristics of the subject's breathing based on the sound signal, determining the phase of the abnormal lung sounds in the inhalation-exhalation cycle, and detecting a cardiac and/or respiratory disease of the subject based on the determined abnormal lung sound characteristics, the determined breathing characteristics and the determined phase of the abnormal lung sounds in the inhalation-exhalation cycle.

公开(公告)号：US11877837B2

公开(公告)日：2024-01-23

申请号：US17440236

申请日：2020-03-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Mark Peter Paul Kleijnen ,  Rick Bezemer ,  Wouter Herman Peeters ,  Gerardus Johannes Nicolaas Doodeman ,  Tim Patrick Steunebrink

IPC: G01R27/28 ,  A61B5/05 ,  G01R27/26 ,  H01Q7/00

CPC classification number: A61B5/05 ,  G01R27/2611 ,  H01Q7/005

Abstract: An apparatus (20) for use in inductive sensing includes a loop antenna (26) and a signal generator (24) for driving the antenna, these forming a resonator circuit (22). The resonator circuit is drivable in a drive state in which the antenna is driven at resonance to thereby generate electromagnetic signals. The arrangement further includes a switching means (28) for switchably inhibiting the drive state of the antenna This allows in use controllable switching of the antenna in and out of the drive state to thereby control switching signal generation on and off.

公开(公告)号：US11375949B2

公开(公告)日：2022-07-05

申请号：US15536918

申请日：2015-12-08

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Nicolaas Lambert ,  Denny Mathew ,  Marcel Cornelis Dirkes ,  Rick Bezemer

IPC: A61B5/00 ,  A61B5/0537

Abstract: There is provided a hydration state indicator. The hydration state indicator comprises a watertight shell; a semi-permeable membrane configured to permit the passage of water molecules and to block the passage of molecules of at least one solute; a water-absorbent indicator layer enclosed by the shell and the membrane; and output means configured to provide an output. The water-absorbent indicator layer has a predetermined osmotic strength. The volume of at least one part of the indicator layer is variable in dependence on the water content of the indicator layer. The output is variable in dependence on the volume of the at least one part of the indicator layer.