公开(公告)号：US20200376167A1

公开(公告)日：2020-12-03

申请号：US16875107

申请日：2020-05-15

Applicant: Korea University Research and Business Foundation ,  Korea Institute of Science and Technology

Inventor： Jong Woong Park ,  Young Mee Jung ,  Soo Hyun Kim ,  Justin Jihong Chung

IPC: A61L27/38 ,  A61L27/54 ,  A61L27/26

Abstract: The present invention relates to a method for preparing of a nerve conduit using bio-printing technology and a nerve conduit prepared by the same, and it can easily prepare a nerve conduit by simulating a nerve bundle and nerve tissue, and the like, by three-dimensionally printing bio-ink comprising a neuronal regeneration material on one side of a porous polymer scaffold.

公开(公告)号：US10206597B2

公开(公告)日：2019-02-19

申请号：US15077172

申请日：2016-03-22

Applicant: Korea Institute of Science and Technology

Inventor： Jinseok Kim ,  Jong Woong Park ,  Jinwoo Jeong ,  Inchan Youn ,  Ockchul Kim ,  Sang Rok Oh ,  Keehoon Kim ,  Jun Uk Chu

IPC: A61B5/04 ,  A61B5/00

Abstract: A nerve probe array has a connector made of a flexible material; and a plurality of probes coupled to the connector, each of the plurality of probe having an electrode formed at a body thereof. The plurality of probes are arranged with intervals in a length direction of the connector, and the connector surrounds an outer circumference of a nerve, and the plurality of probes pierce the outer circumference of the nerve and are inserted into the nerve.

公开(公告)号：US11458305B2

公开(公告)日：2022-10-04

申请号：US15886913

申请日：2018-02-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jinseok Kim ,  Jong Woong Park ,  Hyungdal Park ,  Wonsuk Choi ,  Ockchul Kim ,  Woo Hyun Jung ,  Sunyoung Jung

IPC: A61N1/05 ,  A61B5/00 ,  A61B5/24 ,  A61B17/29

Abstract: A probe insertion device for a neural probe structure with a plurality of probes to simultaneously insert the plurality of probes into a nerve includes a nerve holder to fix the nerve surrounding an outer circumference of the nerve, and a probe holder positioned outside in a radial direction of the nerve holder to fixedly support the probes surrounding a circumference of the nerve holder. The probe holder includes a plurality of sections (“probe holder sections”) arranged radially with respect to the nerve holder and moveable in a radial direction of the nerve holder, and the plurality of probe holder sections simultaneously moves the plurality of probes toward the nerve holder having fixed the nerve, so that the plurality of probes is simultaneously inserted into the nerve in a radial shape when viewed in a lengthwise direction of the nerve.

公开(公告)号：US20180221653A1

公开(公告)日：2018-08-09

申请号：US15886913

申请日：2018-02-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jinseok KIM ,  Jong Woong Park ,  Hyungdal Park ,  Wonsuk Choi ,  Ockchul Kim ,  Woo Hyun Jung ,  Sunyoung Jung

IPC: A61N1/05

CPC classification number: A61N1/0556 ,  A61B5/04001 ,  A61B5/4041 ,  A61B2017/2931 ,  A61B2017/2945 ,  A61B2560/063 ,  A61B2562/0209 ,  A61N1/0558

Abstract: A probe insertion device for a neural probe structure with a plurality of probes to simultaneously insert the plurality of probes into a nerve includes a nerve holder to fix the nerve surrounding an outer circumference of the nerve, and a probe holder positioned outside in a radial direction of the nerve holder to fixedly support the probes surrounding a circumference of the nerve holder. The probe holder includes a plurality of sections (“probe holder sections”) arranged radially with respect to the nerve holder and moveable in a radial direction of the nerve holder, and the plurality of probe holder sections simultaneously moves the plurality of probes toward the nerve holder having fixed the nerve, so that the plurality of probes is simultaneously inserted into the nerve in a radial shape when viewed in a lengthwise direction of the nerve.

公开(公告)号：US11738123B2

公开(公告)日：2023-08-29

申请号：US16891195

申请日：2020-06-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Myoung-Ryul Ok ,  Jimin Park ,  Yu Chan Kim ,  Hyun Kwang Seok ,  Hyung-Seop Han ,  Hojeong Jeon ,  Hyunseon Seo ,  Jee-Wook Lee ,  Jin Kyung Jeon ,  Gayoung Jung ,  Jong Woong Park ,  Ji Hun Park

IPC: A61L31/16 ,  A61B17/86 ,  A61B17/80 ,  A61K9/00 ,  A61K33/00 ,  A61L31/02 ,  F16B35/04 ,  A61F2/28 ,  A61B17/00 ,  C25D11/00

CPC classification number: A61L31/16 ,  A61B17/80 ,  A61B17/8605 ,  A61B17/866 ,  A61F2/2846 ,  A61K9/0024 ,  A61K33/00 ,  A61L31/022 ,  F16B35/04 ,  A61B2017/00893 ,  C25D11/00

Abstract: Provided is an implant having a controlled generation rate of reactive oxygen species and a method of controlling generation of reactive oxygen species using the same. The implant having a controlled generation rate of reactive oxygen species according to the present invention includes a body formed of a metallic material and having a groove, a first filling metal filling one region of the groove, and a second filling metal filling the groove on the first filling metal, wherein the second filling metal has an ionization tendency different from that of the first filling metal.

公开(公告)号：US11607474B2

公开(公告)日：2023-03-21

申请号：US16875107

申请日：2020-05-15

Applicant: Korea University Research and Business Foundation ,  Korea Institute of Science and Technology

Inventor： Jong Woong Park ,  Young Mee Jung ,  Soo Hyun Kim ,  Justin Jihong Chung

IPC: A61L27/38 ,  A61L27/26 ,  A61L27/54

Abstract: The present invention relates to a method for preparing of a nerve conduit using bio-printing technology and a nerve conduit prepared by the same, and it can easily prepare a nerve conduit by simulating a nerve bundle and nerve tissue, and the like, by three-dimensionally printing bio-ink comprising a neuronal regeneration material on one side of a porous polymer scaffold.