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1.
公开(公告)号:US20180305410A1
公开(公告)日:2018-10-25
申请号:US15768356
申请日:2016-10-17
发明人: Ben Hause
IPC分类号: C07K14/005 , C12N7/00 , A61K39/39 , A61K39/12 , A61P31/20
CPC分类号: C07K14/005 , A61K39/12 , A61K39/39 , A61K2039/53 , A61K2039/70 , A61P31/20 , C07K16/081 , C12N7/00 , C12N2750/10021 , C12N2750/10022 , C12N2750/10034
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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公开(公告)号:US20180326040A1
公开(公告)日:2018-11-15
申请号:US15776016
申请日:2016-11-16
发明人: Ben Hause , Emily Collin
IPC分类号: A61K39/145 , C07K14/005
CPC分类号: A61K39/145 , A61K39/12 , A61K2039/5256 , C07K14/005 , C12N7/00 , C12N2760/16022 , C12N2760/16034 , C12N2760/16121 , C12N2760/16122 , C12N2760/16134 , C12N2760/16322
摘要: Attenuated live or replication-deficient chimeric swine influenza virus vaccine, and a platform to develop a multitude of other vaccines in swine and other species. The chimeric influenza virus A comprises a backbone of viral genomic segments derived from influenza A, and expresses a heterologous surface protein (influenza D hemagglutinin esterase fusion protein), and optionally at least one other heterologous protein, such as an antigenic component of a target pathogen.
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3.
公开(公告)号:US20210188919A1
公开(公告)日:2021-06-24
申请号:US17249100
申请日:2021-02-19
发明人: Ben Hause
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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4.
公开(公告)号:US10954274B2
公开(公告)日:2021-03-23
申请号:US16600067
申请日:2019-10-11
发明人: Ben Hause
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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公开(公告)号:US20180303926A1
公开(公告)日:2018-10-25
申请号:US15569641
申请日:2016-04-29
发明人: Ben Hause , Emily Collin , Ying Fang , Lalitha Peddireddi
IPC分类号: A61K39/12 , C12Q1/70 , A61P31/12 , G01N33/569 , A61K39/42
CPC分类号: A61K39/12 , A61K39/42 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61P31/12 , C12N2770/24134 , C12Q1/70 , G01N33/569
摘要: Porcine pestivirus designated herein as atypical porcine pestivirus (“APPV”) (Genbank accession no. KR011347.1). Immunogenic compositions to induce an immune response against porcine pestivirus infection in a pig are described, which APPV antigenic agents (e.g., isolated whole virus, derivatives thereof, functional fragments thereof, and combinations of the foregoing). Methods of vaccinating against porcine pestivirus infection using the immunogenic compositions are also described. The methods can be also applied for clinical research and/or study, including diagnostic methods for detecting pestivirus infection using monoclonal antibodies specifically binding to APPV epitopes.
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6.
公开(公告)号:US20220251144A1
公开(公告)日:2022-08-11
申请号:US17658519
申请日:2022-04-08
发明人: Ben Hause
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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7.
公开(公告)号:US20200031876A1
公开(公告)日:2020-01-30
申请号:US16600067
申请日:2019-10-11
发明人: Ben Hause
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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8.
公开(公告)号:US10450351B2
公开(公告)日:2019-10-22
申请号:US15768356
申请日:2016-10-17
发明人: Ben Hause
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analysis suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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9.
公开(公告)号:US20240092838A1
公开(公告)日:2024-03-21
申请号:US18461369
申请日:2023-09-05
发明人: Ben Hause
CPC分类号: C07K14/005 , A61K39/12 , A61K39/39 , A61P31/20 , C07K16/081 , C12N7/00 , A61K2039/53 , C12N2750/10021 , C12N2750/10022 , C12N2750/10034
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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10.
公开(公告)号:US11780889B2
公开(公告)日:2023-10-10
申请号:US17658519
申请日:2022-04-08
发明人: Ben Hause
CPC分类号: C07K14/005 , A61K39/12 , A61K39/39 , A61P31/20 , C07K16/081 , C12N7/00 , A61K2039/53 , A61K2039/70 , C12N2750/10021 , C12N2750/10022 , C12N2750/10034
摘要: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
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