Actuation method and apparatus, micropump, and PCR enhancement method
    1.
    发明授权
    Actuation method and apparatus, micropump, and PCR enhancement method 有权
    激活方法和装置,微型泵和PCR增强方法

    公开(公告)号:US09091251B1

    公开(公告)日:2015-07-28

    申请号:US13550386

    申请日:2012-07-16

    IPC分类号: G01N21/75 F03G7/06 F04B17/00

    摘要: An actuation apparatus includes at least one magnetic shape memory (MSM) element containing a material configured to expand and/or contract in response to exposure to a magnetic field. Among other things, the MSM element may be configured to pump fluid through a micropump by expanding and/or contracting in response to the magnetic field. The magnetic field may rotate about an axis of rotation and exhibit a distribution having a component substantially perpendicular to the axis of rotation. Further, the magnetic field distribution may include at least two components substantially orthogonal to one another lying in one or more planes perpendicular to the axis of rotation. The at least one MSM element may contain nickel, manganese, and gallium. A polymerase chain reaction (PCR) may be enhanced by contacting a PCR reagent and DNA material with the MSM element.

    摘要翻译: 致动装置包括至少一个磁形状存储器(MSM)元件,其包含被配置为响应于暴露于磁场而膨胀和/或收缩的材料。 除此之外,MSM元件可以被配置成通过响应于磁场的膨胀和/或收缩来泵送流体通过微型泵。 磁场可以围绕旋转轴线旋转并且具有基本上垂直于旋转轴线的分量的分布。 此外,磁场分布可以包括在垂直于旋转轴线的一个或多个平面中彼此基本上正交的至少两个分量。 至少一个MSM元件可以包含镍,锰和镓。 聚合酶链反应(PCR)可以通过使PCR试剂和DNA材料与MSM元件接触来增强。

    Device with magnetoplastic and/or magnetoelastic thin-film transducer and pick-up coil for harvesting energy
    2.
    发明授权
    Device with magnetoplastic and/or magnetoelastic thin-film transducer and pick-up coil for harvesting energy 有权
    具有磁性和/或磁弹性薄膜换能器和拾取线圈的装置,用于收集能量

    公开(公告)号:US08008816B2

    公开(公告)日:2011-08-30

    申请号:US11875732

    申请日:2007-10-19

    IPC分类号: H01L41/00 H02N2/00

    CPC分类号: H01L41/12

    摘要: A magnetoplastic and/or magnetoelastic material transduces linear motion, delivered to it by a mechanical connection, into a change of magnetic field, via twin boundary deformation. A bias magnetic field assures a net change of magnetization during the deformation, and a coil, coaxial with the magnetoplastic/elastic material, couples the magnetic field change to an electrical output. The bias magnetic field or a device that produces strain in a reverse direction resets the magnetomechanical transducer to its initial state. Microgenerators using the magnetoplastic/elastic material may be connected in series or parallel, combined with solar cells, and used to capture energy from passive motion such as random, cyclic or vibrational motion.

    摘要翻译: 通过双边界变形,磁阻和/或磁弹性材料通过机械连接将线性运动转换成磁场的变化。 偏置磁场确保变形期间磁化的净变化,并且与磁/弹性材料同轴的线圈将磁场变化耦合到电输出。 偏置磁场或在相反方向产生应变的器件将磁力机械换能器复位到其初始状态。 使用磁性/弹性材料的微发电机可以与太阳能电池串联或并联连接,并用于从诸如随机,循环或振动运动的被动运动中捕获能量。

    REFERENCE MARKERS FOR BIOLOGICAL SAMPLES
    3.
    发明申请
    REFERENCE MARKERS FOR BIOLOGICAL SAMPLES 审中-公开
    生物样本参考标记

    公开(公告)号:US20150140568A1

    公开(公告)日:2015-05-21

    申请号:US14554106

    申请日:2014-11-26

    申请人: Greg Hampikian

    发明人: Greg Hampikian

    IPC分类号: C12Q1/68 G06F19/22 C07H21/04

    摘要: DNA oligomers comprising sequences that are absent from the genome of one or more organisms of interest are used as reference markers (RMs). The RMs are added to biological samples to “tag” and subsequently identify the samples as authentic and to distinguish tagged samples from samples obtained without said markers, for example, in forensic, medical, legal and other applications.

    摘要翻译: 将包含不存在于一种或多种感兴趣的生物体的基因组的序列的DNA寡聚体用作参考标记(RM)。 将RM添加到生物样品中以“标记”,随后将样品鉴定为真实的,并且区分来自没有所述标记的样品的标记样品,例如在法医,医学,法律和其它应用中。

    REFERENCE MARKERS FOR BIOLOGICAL SAMPLES
    4.
    发明申请
    REFERENCE MARKERS FOR BIOLOGICAL SAMPLES 有权
    生物样本参考标记

    公开(公告)号:US20120115154A1

    公开(公告)日:2012-05-10

    申请号:US13274592

    申请日:2011-10-17

    申请人: Greg Hampikian

    发明人: Greg Hampikian

    IPC分类号: C12Q1/68 C07H1/00 C07H21/00

    摘要: DNA oligomers comprising sequences that are absent from the genome of one or more organisms of interest are used as reference markers (RMs). The RMs are added to biological samples to “tag” and subsequently identify the samples as authentic and to distinguish tagged samples from samples obtained without said markers, for example, in forensic, medical, legal and other applications.

    摘要翻译: 将包含不存在于一种或多种感兴趣的生物体的基因组的序列的DNA寡聚体用作参考标记(RM)。 将RM添加到生物样品中以“标记”,随后将样品鉴定为真实的,并且区分来自没有所述标记的样品的标记样品,例如在法医,医学,法律和其它应用中。

    Absent and Rare Peptides and Therapeutic Uses Thereof
    6.
    发明申请
    Absent and Rare Peptides and Therapeutic Uses Thereof 审中-公开
    缺乏和罕见的肽及其治疗用途

    公开(公告)号:US20140249293A1

    公开(公告)日:2014-09-04

    申请号:US13358952

    申请日:2012-01-26

    申请人: Greg Hampikian

    发明人: Greg Hampikian

    IPC分类号: G06F17/30 C07K7/06

    CPC分类号: C07K7/06 G01N33/6803

    摘要: The present invention relates to methods for searching and identifying absent and rare peptide sequences from public databases and their uses in the treatment of pathological diseases. One embodiment of the present invention provides a method that includes: a) storing, in a memory or storage of a computing device, a set of at least one peptide sequence of fixed length; b) searching, by the computing device, for a peptide sequence from the set within at least one database having naturally-occurring amino acid sequences; and c) classifying, by the number of appearance in the database, the peptide sequence.

    摘要翻译: 本发明涉及从公共数据库中搜索和鉴定不存在和罕见的肽序列的方法及其在治疗病理疾病中的用途。 本发明的一个实施方案提供了一种方法,其包括:a)在计算设备的存储器或存储器中存储固定长度的至少一个肽序列的集合; b)由计算设备从具有天然存在的氨基酸序列的至少一个数据库内的集合中搜索肽序列; 和c)通过数据库中出现的数目来分类肽序列。

    Reference markers for biological samples
    7.
    发明授权
    Reference markers for biological samples 有权
    生物样品的参考标记

    公开(公告)号:US08927213B2

    公开(公告)日:2015-01-06

    申请号:US13274592

    申请日:2011-10-17

    申请人: Greg Hampikian

    发明人: Greg Hampikian

    IPC分类号: C07H21/04 C12Q1/68

    摘要: DNA oligomers comprising sequences that are absent from the genome of one or more organisms of interest are used as reference markers (RMs). The RMs are added to biological samples to “tag” and subsequently identify the samples as authentic and to distinguish tagged samples from samples obtained without said markers, for example, in forensic, medical, legal and other applications.

    摘要翻译: 将包含不存在于一种或多种感兴趣的生物体的基因组的序列的DNA寡聚体用作参考标记(RM)。 将RM添加到生物样品中以“标记”,随后将样品鉴定为真实的,并且区分来自没有所述标记的样品的标记样品,例如在法医,医学,法律和其它应用中。

    Reference markers for biological samples
    8.
    发明申请
    Reference markers for biological samples 审中-公开
    生物样品的参考标记

    公开(公告)号:US20080138798A1

    公开(公告)日:2008-06-12

    申请号:US11024293

    申请日:2004-12-23

    申请人: Greg Hampikian

    发明人: Greg Hampikian

    IPC分类号: C12Q1/68 C07H21/00

    CPC分类号: C12Q1/68 C12Q2563/185

    摘要: The present invention provides methods, compositions and kits that include reference markers in biological samples. The reference samples can be marked with DNA oligomers that can be derived from sequences that do not to exist in the human genome. These sequences can be determined by an algorithm used to search published genomes for the shortest sequences which are not present (“nullomers”). Such reference markers can be used in forensic, medical, legal or other applications.

    摘要翻译: 本发明提供在生物样品中包括参考标记的方法,组合物和试剂盒。 参考样品可以用可以从不存在于人类基因组中的序列衍生的DNA寡聚体标记。 这些序列可以通过用于搜索未出现的最短序列的公布的基因组的算法来确定(“nullomers”)。 这些参考标记可用于法医,医疗,法律或其他应用。