-
公开(公告)号：US20060134266A1
公开(公告)日：2006-06-22
申请号：US11224218
申请日：2005-09-12
CPC分类号： C12N9/2417
摘要： An enzyme is described which enzyme is derived from family 13 of α-amylases. The enzyme variant is obtainable by modifying a CGTase or a maltogenic α-amylase. The enzyme is useful in preparing a food or a food product such as bakery products.
摘要翻译： 描述了一种酶来源于α-淀粉酶家族13的酶。 酶变体可通过修饰CGT酶或麦芽糖α-淀粉酶获得。 该酶可用于制备食品或食品如面包店产品。
-
公开(公告)号：US06777215B2
公开(公告)日：2004-08-17
申请号：US09816721
申请日：2001-03-22
IPC分类号： C12P2106
CPC分类号： C12N9/1074 , C12P19/18 , C12Y204/01019
摘要： The present invention relates to variants of cyclomaltodextrin glucanotransferase of increased product specificity.
摘要翻译： 本发明涉及增加产品特异性的环糊精葡聚糖转移酶的变体。
-
公开(公告)号：US06271010B1
公开(公告)日：2001-08-07
申请号：US09158216
申请日：1998-09-22
IPC分类号： C12N900
CPC分类号： C12N9/1074 , C12P19/18 , C12Y204/01019
摘要： The present invention relates to variants of cyclomaltodextrin glucanotransferase of increased product specificity.
摘要翻译： 本发明涉及增加产品特异性的环糊精葡聚糖转移酶的变体。
-
4.发明授权Cyclodextrin glycosyltransferase (CGTase) polypeptides with modified hydrolysis activity 有权具有改性水解活性的环糊精糖基转移酶（CGTase）多肽公开(公告)号：US07803598B2
公开(公告)日：2010-09-28
申请号：US11224218
申请日：2005-09-12
CPC分类号： C12N9/2417
摘要： An enzyme is described which enzyme is derived from family 13 of α-amylases. The enzyme variant is obtainable by modifying a CGTase or a maltogenic α-amylase. The enzyme is useful in preparing a food or a food product such as bakery products.
摘要翻译： 描述了一种酶来源于α-淀粉酶家族13的酶。 酶变体可通过修饰CGT酶或麦芽糖α-淀粉酶获得。 该酶可用于制备食品或食品如面包店产品。
-
公开(公告)号：US09657322B2
公开(公告)日：2017-05-23
申请号：US13319237
申请日：2010-05-10
申请人： Lubbert Dijkhuizen , Marc Jos Elise Cornelis van der Maarel , Johannis Paulus Kamerling , Reinder Johannes Leemhuis , Slavko Kralj , Justyna Malgorzata Dobruchowska
发明人： Lubbert Dijkhuizen , Marc Jos Elise Cornelis van der Maarel , Johannis Paulus Kamerling , Reinder Johannes Leemhuis , Slavko Kralj , Justyna Malgorzata Dobruchowska
CPC分类号： C12P19/00 , C12N9/1051 , C12P19/04 , C12Y204/01005
摘要： The invention relates to the field of poly-and oligosaccharides and their nutritional effects. In particular, it relates to the application of α-glucanotransferases in methods for preparing dietary fibers, including prebiotic oligosaccharides, and to novel oligosaccharides obtainable thereby. Provided is a method for producing a mixture of gluco-oligosaccharides having one or more consecutive (α1→6) glucosidic linkages and one or more consecutive (α1→4) glucosidic linkages, comprising contacting a poly- and/or oligosaccharide substrate comprising at least two (α1→4) linked D-glucose units with an α-glucanotransferase capable of cleaving (α1→4) glucosidic linkages and making new (α1→4) and (α1→6) glucosidic linkages. Also provided are (isolated) gluco-oligosaccharides obtainable thereby, and their application in nutritional and cosmetic compositions.
-
6.发明申请Method for the Production of Modified Steroid Degrading Microorganisms and their Use 审中-公开改性类固醇降解微生物生产方法及其应用公开(公告)号：US20090186390A1
公开(公告)日：2009-07-23
申请号：US12194903
申请日：2008-08-20
摘要： A method is described to construct genetically modified strains of steroid degrading micro-organisms wherein the method comprises inactivation of at least one gene involved in methylhexahydroindanedione propionate degradation. Strains with (multiple) inactivated steroid degrading enzyme genes according to the invention can be used in the accumulation of steroid intermediates. Accumulation products are for example 3aα-H-4α(3′-propionic acid)-7aβ-methylhexahydro-1,5-indanedione (HIP), 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3-HSA), 1,4-androstadiene-3,17-dione (ADD) and 3aα-H-4α(3′-propionic acid)-5α-hydroxy-7aβ-methylhexahydro-1-indanone-δ-lactone (HIL).
摘要翻译： 描述了一种构建基因修饰的类固醇降解微生物菌株的方法，其中所述方法包括使参与甲基六氢茚满酮丙酸酯降解的至少一个基因的失活。 具有根据本发明的（多个）灭活的类固醇降解酶基因的菌株可用于类固醇中间体的积累。 累积产物是例如3aalpha-H-4alpha（3'-丙酸）-7β-甲基六氢-1,5-茚二酮（HIP），3-羟基-9,10-雄甾-1,3,5（10） - 三烯-9,17-二酮（3-HSA），1,4-雄甾二烯-3,17-二酮（ADD）和3aalpha-H-4α（3'-丙酸）-5α-羟基-7β-甲基六氢-1 - 茚满酮-δ-内酯（HIL）。
-
7.发明授权Indentification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity 失效3-酮类化合物9-α-羟化酶基因和微生物在3-酮类固醇9-α-羟化酶活性中的鉴定公开(公告)号：US07432075B2
公开(公告)日：2008-10-07
申请号：US11695809
申请日：2007-04-03
CPC分类号： C12N9/0071 , C12P33/00
摘要： The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499-1695 of SEQ ID NO:1 or by nucleotides 387-1427 of SEQ ID NO:2, respectively, and functional homologues thereof.The polynucleotides of the invention can be used to construct genetically modified microorganisms blocked in 3-ketosteroid 9α-hydroxylase activity, which are useful in the microbial degradation of steroids to accumulate certain steroid products.
摘要翻译： 本发明涉及分离的多核苷酸序列，其包含编码由SEQ ID NO：1的核苷酸499-1695或SEQ ID NO：2的核苷酸387-1427编码的KshA蛋白或KshB蛋白的氨基酸序列的核酸序列 ，及其功能同系物。 本发明的多核苷酸可用于构建在3-酮类固醇9α-羟化酶活性中封闭的遗传修饰微生物，其可用于类固醇的微生物降解以积聚某些类固醇产物。
-
公开(公告)号：US20060172423A1
公开(公告)日：2006-08-03
申请号：US10537201
申请日：2003-12-02
摘要： The present invention provides an isolated polynucleotide comprising the kstD promoter from Rhodococcus erythrypolis. The polynucleotide can very advantageously be used as a controllable transcription activator. Said controlling function can be provided by providing said isolated polynucleotide with a nucleotide sequence encoding a transcription regulator of said promoter. In the present invention, such a transcription regulator may be externally induced, such as by introduction of steroidal compounds. In an alternative embodiment of the present invention the isolated polynucleotide may comprise the kstR gene or a homologue or a functional part thereof as the transcription regulator of the kstD promoter.
摘要翻译： 本发明提供了包含来自红球菌的kstD启动子的分离的多核苷酸。 多核苷酸可以非常有利地用作可控转录激活因子。 可以通过向所述分离的多核苷酸提供编码所述启动子的转录调节子的核苷酸序列来提供所述控制功能。 在本发明中，这种转录调节剂可以通过引入甾族化合物而被外部诱导。 在本发明的替代实施方案中，分离的多核苷酸可以包含kstR基因或其同源物或其功能部分作为kstD启动子的转录调节子。
-
9.发明授权公开(公告)号：US08574565B2
公开(公告)日：2013-11-05
申请号：US13144042
申请日：2010-01-11
CPC分类号： A61K35/74
摘要： The invention pertains to a pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.
摘要翻译： 本发明涉及一种药物组合物，用于保护动物免受属于具有在动物巨噬细胞内存活的能力的诺卡氏菌素放线菌群的细菌的感染引起的疾病，其包括诺卡氏菌放线菌种的活细菌， 活细菌通过灭活编码参与甲基六氢茚二酮丙酸酯降解的蛋白质的基因而减弱，以及用于这些活细菌的药学上可接受的载体。
-
10.发明申请PHARMACEUTICAL COMPOSITION TO PROTECT AN ANIMAL AGAINST A DISORDER ARISING FROM AN INFECTION WITH A BACTERIUM THAT BELONGS TO THE GROUP OF NOCARDIOFORM ACTINOMYCETES 有权药物组合物，用于保护动物与抗菌药物相关的细菌感染的动物，其中包括与乙酰胆碱酯酶基团一致的细菌公开(公告)号：US20110274660A1
公开(公告)日：2011-11-10
申请号：US13144042
申请日：2010-01-11
CPC分类号： A61K35/74
摘要： The invention pertains to a pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.
摘要翻译： 本发明涉及一种药物组合物，用于保护动物免受属于具有在动物巨噬细胞内存活的能力的诺卡氏菌素放线菌群的细菌的感染引起的疾病，其包括诺卡氏菌放线菌种的活细菌， 活细菌通过灭活编码参与甲基六氢茚二酮丙酸酯降解的蛋白质的基因而减弱，以及用于这些活细菌的药学上可接受的载体。
-
-
-
-
-
-
-
-
-
搜索结果
24 条记录 (耗时 0.021 秒)
