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    Method for reductive elimination of protecting groups
    1.
    发明授权
    Method for reductive elimination of protecting groups 失效
    还原消除保护基团的方法

    公开(公告)号：US4564471A

    公开(公告)日：1986-01-14

    申请号：US188107

    申请日：1980-09-17

    申请人： Katsumi Sugiyama ,  Hideo Takeda ,  Hiroko Sato ,  Yuji Nonaka ,  Kiyotaka Oyama ,  Masashige Kubo

    发明人： Katsumi Sugiyama ,  Hideo Takeda ,  Hiroko Sato ,  Yuji Nonaka ,  Kiyotaka Oyama ,  Masashige Kubo

    IPC分类号： C07B31/00 ,  C07B51/00 ,  C07C67/00 ,  C07C227/00 ,  C07C227/16 ,  C07C227/18 ,  C07C227/20 ,  C07C231/00 ,  C07K1/06 ,  C07K1/12 ,  C07K5/075 ,  C07C101/02

    CPC分类号： C07K1/12 ,  C07K5/0613 ,  Y02P20/55

    摘要： The invention provides a novel and efficient method for the elimination of protecting groups, e.g. benzyloxycarbonyl group, from a protected amino acid, peptide or derivative thereof having at least one functional group protected by a protecting group, e.g. a lower alkyl ester of N-benzyloxycarbonyl-.alpha.-L-aspartyl-L-phenylalanine by catalytic hydrogen reduction to produce free amino acid, peptide or derivative thereof. In contrast to the conventional procedures in which the reaction is carried out in a solvent dissolving both the starting compound and the product compound or a solvent dissolving the starting compound but not dissolving the product compound, the inventive method utilizes a binary two-phase reaction medium composed of water and an organic solvent not freely miscible with water such as toluene. The reaction takes place in the organic phase containing the starting compound dissolved and the catalyst dispersed therein whereas the reaction product which is water-soluble is smoothly and successively transferred into the aqueous phase so that advantages are obtained in the unexpectedly high yield of the product as well as in the easiness of handling the reaction mixture after completion of the reaction.

    摘要翻译： 本发明提供了一种用于消除保护基团的新型和有效的方法，例如， 苄氧羰基，被保护的氨基酸，具有至少一个被保护基保护的官能团的肽或衍生物。 N-苄氧羰基-α-L-天冬氨酰基-L-苯丙氨酸的低级烷基酯通过催化氢还原反应产生游离氨基酸，肽或其衍生物。 与在溶解起始化合物和产物化合物的溶剂或溶解起始化合物但不溶解产物化合物的溶剂中进行反应的常规方法相反，本发明的方法利用二元二相反应介质 由水和不能与水如甲苯自由混溶的有机溶剂组成。 反应发生在含有溶解的起始化合物和分散在其中的催化剂的有机相中，而水溶性的反应产物顺利地依次转移到水相中，从而获得了产品出乎意料的高产率的优点， 以及在反应完成后容易处理反应混合物。

    Method of producing N-benzyloxycarbonyl-L-aspartic acid
    2.
    发明授权
    Method of producing N-benzyloxycarbonyl-L-aspartic acid 失效
    制备N-苄氧羰基-L-天冬氨酸的方法

    公开(公告)号：US4345091A

    公开(公告)日：1982-08-17

    申请号：US224477

    申请日：1981-01-12

    申请人： Katsumi Sugiyama ,  Hideo Takeda ,  Hiroko Sato

    发明人： Katsumi Sugiyama ,  Hideo Takeda ,  Hiroko Sato

    IPC分类号： C07C271/22 ,  C07C67/00 ,  C07C239/00 ,  C07K5/075 ,  C07C125/06

    CPC分类号： C07K5/0613

    摘要： The reaction between L-aspartic acid and benzyloxycarbonyl chloride is carried out at a specific pH range, i.e., 12.0 to 13.5, whereby highly pure N-benzyloxycarbonyl-L-aspartic acid can be obtained in high yields, while both the by-production of N-benzyloxycarbonyl-.alpha.- or .beta.-L-aspartyl-L-aspartic acid and the decomposition of benzyloxycarbonyl chloride to benzyl alcohol are suppressed.

    摘要翻译： L-天冬氨酸与苄氧羰基氯之间的反应在特定的pH范围内进行，即12.0至13.5，从而可以高产率获得高纯度的N-苄氧羰基-L-天冬氨酸，而副产物 N-苄氧羰基-α-或β-L-天冬氨酰-L-天门冬氨酸和苄氧羰基氯分解成苄醇被抑制。

    Liquid crystal display system capable of reducing and enlarging resolution of input display data
    4.
    发明授权
    Liquid crystal display system capable of reducing and enlarging resolution of input display data 失效
    能够降低和扩大输入显示数据分辨率的液晶显示系统

    公开(公告)号：US6118429A

    公开(公告)日：2000-09-12

    申请号：US315714

    申请日：1994-09-30

    申请人： Naruhiko Kasai ,  Toshio Tanaka ,  Hiroyuki Mano ,  Shigeyuki Nishitani ,  Mitsutoshi Uchida ,  Kazuko Hasegawa ,  Tetsuya Suzuki ,  Shinji Wakisaka ,  Hiroko Sato ,  Tatsuzo Hamada

    发明人： Naruhiko Kasai ,  Toshio Tanaka ,  Hiroyuki Mano ,  Shigeyuki Nishitani ,  Mitsutoshi Uchida ,  Kazuko Hasegawa ,  Tetsuya Suzuki ,  Shinji Wakisaka ,  Hiroko Sato ,  Tatsuzo Hamada

    IPC分类号： G09G3/36 ,  G09G3/18

    CPC分类号： G09G3/3611 ,  G09G2340/0414 ,  G09G2340/0421 ,  G09G2360/02

    摘要： A liquid crystal display system which can accept display data having a resolution different from that of a screen for the liquid crystal display and display the display data. For example, a CPU outputs display data of 1120.times.780 dots and a liquid crystal panel has a 1024.times.768-dot resolution which is smaller than the display data resolution. The display screen of the liquid crystal panel comprises a linear arrangement of pixels. A data conversion section generates display data for a new horizontal or vertical line based on display data for two horizontal or vertical lines contiguous to each other and repeats replacement of display data of the two lines with the display data of the one line for reducing the number of horizontal lines of one screen and the number of dots of one line so as to match the resolution of the display data output by the CPU with the liquid crystal display. In contrast, if the resolution of the display data is smaller than the screen resolution of the liquid crystal panel, the data conversion section inserts the display data of the new one horizontal or vertical line between the two contiguous lines for enlarging the resolution of the display data.

    摘要翻译： 一种液晶显示系统，其能够接受与液晶显示器的屏幕分辨率不同的显示数据，并显示显示数据。 例如，CPU输出1120×780点的显示数据，液晶面板的1024×768点分辨率小于显示数据分辨率。 液晶面板的显示屏包括像素的线性排列。 数据转换部分基于两条相邻的两条水平或垂直线的显示数据，生成新的水平线或垂直线的显示数据，并用一条线的显示数据重复替换两行的显示数据，以减少数字 一个屏幕的水平线和一行的点数，以便将CPU输出的显示数据的分辨率与液晶显示器相匹配。 相反，如果显示数据的分辨率小于液晶面板的屏幕分辨率，则数据转换部分插入两条连续线之间的新的一条水平或垂直线的显示数据，以扩大显示器的分辨率 数据。

    Method and system for creating user interface independent programs with a user interface provider
    6.
    发明授权
    Method and system for creating user interface independent programs with a user interface provider 失效
    用户界面提供程序创建用户界面独立程序的方法和系统

    公开(公告)号：US5754173A

    公开(公告)日：1998-05-19

    申请号：US607939

    申请日：1996-02-28

    申请人： Hideki Hiura ,  Hiroko Sato

    发明人： Hideki Hiura ,  Hiroko Sato

    IPC分类号： G06F13/10 ,  G06F3/14 ,  G06F9/06 ,  G06F9/44 ,  G06F3/114

    CPC分类号： G06F9/4448

    摘要： An apparatus and method for separating the design and implementation of a user interface ("the user interface logic") from the design and implementation of the functional portion of a software program (the "core logic"). The present invention uses an object-oriented programming model in which one or more look and feel agents act as servers for one or more logic objects. The look and feel agent controls the appearance and behavior of the user interface, while a logic objects perform the functions of the software program. A look and feel agent does not "know" what functions constitute the core logic and the logic objects do not "know" what the user interface looks like or how it behaves.

    摘要翻译： 一种用于将用户界面（“用户界面逻辑”）的设计和实现与软件程序的功能部分（“核心逻辑”）的设计和实现分离的装置和方法。 本发明使用面向对象的编程模型，其中一个或多个外观感知代理充当用于一个或多个逻辑对象的服务器。 外观和感觉代理控制用户界面的外观和行为，而逻辑对象执行软件程序的功能。 外观和代理不会“知道”什么功能构成核心逻辑，而逻辑对象不会“知道”用户界面的外观或行为方式。

    Liquid crystal display system capable of reducing and enlarging resolution of input display data
    10.
    发明授权
    Liquid crystal display system capable of reducing and enlarging resolution of input display data 有权
    能够降低和扩大输入显示数据分辨率的液晶显示系统

    公开(公告)号：US06310602B1

    公开(公告)日：2001-10-30

    申请号：US09614910

    申请日：2000-07-12

    申请人： Naruhiko Kasai ,  Toshio Tanaka ,  Hiroyuki Mano ,  Shigeyuki Nishitani ,  Mitsutoshi Uchida ,  Kazuko Hasegawa ,  Tetsuya Suzuki ,  Shinji Wakisaka ,  Hiroko Sato ,  Tatsuzo Hamada

    发明人： Naruhiko Kasai ,  Toshio Tanaka ,  Hiroyuki Mano ,  Shigeyuki Nishitani ,  Mitsutoshi Uchida ,  Kazuko Hasegawa ,  Tetsuya Suzuki ,  Shinji Wakisaka ,  Hiroko Sato ,  Tatsuzo Hamada

    IPC分类号： G09G318

    CPC分类号： G09G3/3611 ,  G09G2340/0414 ,  G09G2340/0421 ,  G09G2360/02

    摘要： A liquid crystal display system which can accept display data having a resolution different from that of a screen for the liquid crystal display and display the display data. For example, a CPU outputs display data of 1120×780 dots and a liquid crystal panel has a 1024×768-dot resolution which is smaller than the display data resolution. The display screen of the liquid crystal panel comprises a linear arrangement of pixels. A data conversion section generates display data for a new horizontal or vertical line based on display data for two horizontal or vertical lines contiguous to each other and repeats replacement of display data of the two lines with the display data of the one line for reducing the number of horizontal lines of one screen and the number of dots of one line so as to match the resolution of the display data output by the CPU with the liquid crystal display. In contrast, if the resolution of the display data is smaller than the screen resolution of the liquid crystal panel, the data conversion section inserts the display data of the new one horizontal or vertical line between the two contiguous lines for enlarging the resolution of the display data.

    摘要翻译： 一种液晶显示系统，其能够接受与液晶显示器的屏幕分辨率不同的显示数据，并显示显示数据。 例如，CPU输出1120×780点的显示数据，液晶面板的1024×768点分辨率小于显示数据分辨率。 液晶面板的显示屏包括像素的线性排列。 数据转换部分基于两条相邻的两条水平或垂直线的显示数据，生成新的水平线或垂直线的显示数据，并用一条线的显示数据重复替换两行的显示数据，以减少数字 一个屏幕的水平线和一行的点数，以便将CPU输出的显示数据的分辨率与液晶显示器相匹配。 相反，如果显示数据的分辨率小于液晶面板的屏幕分辨率，则数据转换部分插入两条连续线之间的新的一条水平或垂直线的显示数据，以扩大显示器的分辨率 数据。