公开(公告)号：US5246841A

公开(公告)日：1993-09-21

申请号：US781659

申请日：1991-10-25

申请人： Kazunaga Yazawa ,  Keiko Araki ,  Noriko Okazaki ,  Naganori Numao ,  Kiyosi Kondo

发明人： Kazunaga Yazawa ,  Keiko Araki ,  Noriko Okazaki ,  Naganori Numao ,  Kiyosi Kondo

IPC分类号： C12P7/64

CPC分类号： C12P7/6427 ,  C12P7/6472 ,  Y10S435/822 ,  Y10S435/876

摘要： A process for the production of eicosapentaenoic acid comprising the steps of a) culturing a microorganism capable of producing lipid containing eicosapentaenoic acid belonging to a genus selected from the group of Pseudomonas, Alteromonas and Shewanella, to produce lipid containing eicosapentaenoic acid, and b) recovering the eicosapentaenoic acid from the cultured product; a process for production of a lipid containing eicosapentaenoic acid comprising the steps of a) culturing a microorganism capable of producing lipid containing eicosapentaenoic acid belonging to a genus selected from the group of Pseudomonas, Alteromonas and Shewanella, to produce lipid containing eicosapentaenoic acid, and b) recovering the lipid containing eicosapentaenoic acid; and microorganisms capable of producing eicosapentaenoic acid belonging to a genus selected from the group consisting of Pseudomonas, Alteromonas, and Shewanella.

摘要翻译： 一种生产二十碳五烯酸的方法，包括以下步骤：a）培养能够产生属于选自假单胞菌属，异黄酮和希瓦氏菌属的属于二十碳五烯酸的脂质的微生物，以产生含有二十碳五烯酸的脂质，和b）回收 来自培养产物的二十碳五烯酸; 一种生产含有二十碳五烯酸的脂质的方法，包括以下步骤：a）培养能够产生属于选自假单胞菌属，异黄酮和希瓦氏菌属的属于二十碳五烯酸的脂质的微生物，以产生含有二十碳五烯酸的脂质，b ）回收含有二十碳五烯酸的脂质; 以及能够产生属于选自假单胞菌属，变形单子菌属和希瓦氏菌属的属的二十碳五烯酸的微生物。

公开(公告)号：US4849345A

公开(公告)日：1989-07-18

申请号：US851207

申请日：1986-04-14

申请人： Yasuhisa Asano ,  Akiko Nakazawa ,  Shiro Terashima ,  Kiyosi Kondo ,  Kaori Endo ,  Kenji Hirai ,  Naganori Numao

发明人： Yasuhisa Asano ,  Akiko Nakazawa ,  Shiro Terashima ,  Kiyosi Kondo ,  Kaori Endo ,  Kenji Hirai ,  Naganori Numao

IPC分类号： C12N9/06 ,  C12P1/00 ,  C12P13/04

CPC分类号： C12N9/0018 ,  C12N9/0028 ,  C12P1/00 ,  C12P13/04 ,  Y10S435/822 ,  Y10S435/832

摘要： New L-phenylalanine dehydrogenases produced by a microorganism belonging to the genus Sporosarcina or Bacillus, new microorganisms capable of l-phenylalanine dehydrogenase and belonging to the genus Sporosarcina or Bacillus, a process for production of L-phenylalanine dehydrogenase using the microorganisms, and processes for production of L-amino acids using the enzymes or the microorganisms.

公开(公告)号：US5015582A

公开(公告)日：1991-05-14

申请号：US521641

申请日：1990-05-10

申请人： Yasuo Hibino ,  Yasuhisa Asano ,  Noriko Okazaki ,  Naganori Numao

发明人： Yasuo Hibino ,  Yasuhisa Asano ,  Noriko Okazaki ,  Naganori Numao

IPC分类号： C12N1/21 ,  C12N9/06 ,  C12N15/53 ,  C12P13/22

CPC分类号： C12N9/0018 ,  C12N9/0028 ,  C12P13/222

摘要： An isolated gene coding for phenylalanine dehydrogenase of a microorganism belonging to a genus selected from the group consisting of the genera Bacillus and Sporosarcina origin; plasmids containing the gene; microorganism transformed with the plasmid, a process for the production of phenylalanine dehydrogenase using the microorganism; and a process for the production of L-phenylalanine using the enzyme.

公开(公告)号：US4970157A

公开(公告)日：1990-11-13

申请号：US84238

申请日：1987-08-11

申请人： Yasuo Hibino ,  Yasuhisa Asano ,  Noriko Okazaki ,  Naganori Numao

发明人： Yasuo Hibino ,  Yasuhisa Asano ,  Noriko Okazaki ,  Naganori Numao

IPC分类号： C12N1/21 ,  C12N9/06 ,  C12N15/53 ,  C12P13/22

CPC分类号： C12N9/0018 ,  C12N9/0028 ,  C12P13/222

摘要： An isolated gene coding for phenylalanine dehydrogenase of a microorganism belonging to a genus selected from the group consisting of the genera Bacillus and Sporosarcina origin; plasmids containing the gene; microorganism transformed with the plasmid, a process for the production of phenylalanine dehydrogenase using the microogranism; and a process for the production of L-phenylalanine using the enzyme.

摘要翻译： 编码属于选自芽孢杆菌属和孢子纲属的属的微生物的苯丙氨酸脱氢酶的分离基因; 含有该基因的质粒; 用质粒转化的微生物，使用微观色谱法生产苯丙氨酸脱氢酶的方法; 以及使用该酶生产L-苯丙氨酸的方法。

公开(公告)号：US5204255A

公开(公告)日：1993-04-20

申请号：US726129

申请日：1991-07-03

申请人： Michito Tagawa ,  Masakatsu Wada ,  Masayuki Yamada ,  Midori Yokoyama ,  Naganori Numao

发明人： Michito Tagawa ,  Masakatsu Wada ,  Masayuki Yamada ,  Midori Yokoyama ,  Naganori Numao

IPC分类号： A61K38/00 ,  C12N9/72 ,  C12N15/70

CPC分类号： C12N9/6456 ,  C12N15/70 ,  A61K38/00 ,  C07K2319/00

摘要： A hybrid plasminogen activator-like polypeptide comprising a polypeptide region responsible for an affinity to fibrin derived from a tissue plasminogen activator polypeptide and a polypeptide region responsible for an enzyme activity derived from a prourokinase polypeptide; a DNA segment coding for the hybrid polypeptide; plasmid containing the DNA segment; a microorganism transformed with the DNA; and a process for production of the hybrid polypeptide comprising culturing the microorganism and recovering the hybrid polypeptide from the cultured cells.

摘要翻译： 一种杂合纤维蛋白溶酶原激活剂样多肽，其包含负责来自组织纤溶酶原激活剂多肽的纤维蛋白亲和力的多肽区域和负责源自原尿激酶多肽的酶活性的多肽区域; 编码杂合多肽的DNA区段; 含有DNA片段的质粒; 用DNA转化的微生物; 以及杂交多肽的制备方法，包括培养微生物并从培养的细胞中回收杂交多肽。