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公开(公告)号:USD616311S1
公开(公告)日:2010-05-25
申请号:US29315074
申请日:2009-05-23
申请人: Quran Buchanan , Ken Hill , Mitchell Jessie
设计人: Quran Buchanan , Ken Hill , Mitchell Jessie
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公开(公告)号:US06737236B1
公开(公告)日:2004-05-18
申请号:US09341337
申请日:1999-07-08
申请人: Wolfgang Pieken , Ken Hill , Bruce Eaton , Danny McGee , Kurt Vagle , Larry Gold , Andrew Stephens
发明人: Wolfgang Pieken , Ken Hill , Bruce Eaton , Danny McGee , Kurt Vagle , Larry Gold , Andrew Stephens
IPC分类号: C12Q168
CPC分类号: C12N15/113 , B01J2219/00423 , B01J2219/00452 , B01J2219/00497 , B01J2219/00527 , B01J2219/00599 , B01J2219/00686 , B01J2219/00707 , B01J2219/00722 , B01J2219/00725 , C07B2200/11 , C07C271/22 , C07C2603/18 , C07H19/04 , C07H19/10 , C07H21/00 , C07K1/023 , C07K1/063 , C12N2310/351 , C40B40/06 , C40B40/10 , C40B50/08 , C40B60/14
摘要: This invention discloses a novel method for conjugating macromolecules to other molecular entities. Specifically, this invention discloses a method for conjugating or derivatizing macromolecules, such as oligonucleotides and proteins, using cycloaddition reactions, such as the Diels-Alder reaction or 1,3-dipolar cycloadditions. Included in the invention are the novel bioconjugated macromolecules that can be prepared according to the method of the invention.
摘要翻译: 本发明公开了一种将大分子与其他分子实体结合的新方法。 具体地说,本发明公开了一种使用环加成反应如Diels-Alder反应或1,3-偶极环加成来共轭或衍生大分子如寡核苷酸和蛋白质的方法。 本发明包括可根据本发明方法制备的新型生物共轭大分子。
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公开(公告)号:US07008136B2
公开(公告)日:2006-03-07
申请号:US10707101
申请日:2003-11-20
申请人: Ken Hill
发明人: Ken Hill
IPC分类号: E01C23/02
CPC分类号: E01C19/174 , E01C23/0973
摘要: A crack sealing apparatus having a heated hose trough is presented which eliminates the need to purge or clean the hose and/or applicator wand that is used to apply sealant to cracks in a roadway. In accordance with one embodiment of the invention, the crack sealing apparatus includes a repository for storing and heating sealant, a hose attached to the repository, a pump for transporting sealant from the repository through the hose, a trough for retaining and heating the hose, and a tubular member located within the trough having a hot liquid or gas circulating therethrough for heating sealant contained within the hose.
摘要翻译: 提供了一种具有加热软管槽的裂缝密封装置,其不需要清洗或清洁用于将道路施加密封剂用于裂缝的软管和/或施加器棒。 根据本发明的一个实施例,裂缝密封装置包括用于储存和加热密封剂的储存库,附着在贮存库的软管,用于通过软管从贮存库输送密封剂的泵,用于保持和加热软管的槽, 并且位于槽内的管状构件具有在其中循环的热液体或气体,用于加热容纳在软管内的密封剂。
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