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    Methods and apparatus for monitoring physiological responses to steady state activity
    1.
    发明申请
    Methods and apparatus for monitoring physiological responses to steady state activity 审中-公开
    监测对稳态活动的生理反应的方法和装置

    公开(公告)号：US20070021678A1

    公开(公告)日：2007-01-25

    申请号：US11184327

    申请日：2005-07-19

    申请人： Kenneth Beck ,  Lemont Baker ,  Donald Hopper

    发明人： Kenneth Beck ,  Lemont Baker ,  Donald Hopper

    IPC分类号： A61B5/04 ,  A61B5/02 ,  A61B5/08

    CPC分类号： A61B5/0245 ,  A61B5/0215 ,  A61B5/029 ,  A61B5/0816 ,  A61B5/1116 ,  A61B5/145 ,  A61B5/686 ,  A61B2560/0468 ,  A61B2562/0219 ,  A61N1/36585 ,  A61N1/37

    摘要： This document discusses, among other things, methods of monitoring physiological responses to steady state activity. In an example, a physical activity signal is detected from a human or animal subject using an implantable medical device. A different, other physiological signal is also detected from the subject using the implantable medical device. The physical activity signal is processed to define first and second time periods associated with first and second steady-state physical activity levels of the subject. A first indicator is obtained by combining data from the other physiological signal obtained during the first time period. A second indicator is obtained by combining data from the other physiological signal obtained during the second time period. The first and second indicators are used provide a diagnostic indicator.

    摘要翻译： 本文件还讨论了监测对稳态活动的生理反应的方法。 在一个示例中，使用可植入医疗装置从人或动物受试者检测身体活动信号。 使用可植入医疗装置也可以从对象检测不同的其他生理信号。 处理身体活动信号以定义与受试者的第一和第二稳态身体活动水平相关联的第一和第二时间段。 通过组合来自第一时间段期间获得的其他生理信号的数据获得第一指示符。 通过组合来自在第二时间段期间获得的其他生理信号的数据获得第二指示符。 使用第一和第二指标提供诊断指标。

    Method and apparatus for monitoring heart failure patients with cardiopulmonary comorbidities
    4.
    发明授权
    Method and apparatus for monitoring heart failure patients with cardiopulmonary comorbidities 有权
    监测心肺合并症心力衰竭患者的方法和装置

    公开(公告)号：US07480528B2

    公开(公告)日：2009-01-20

    申请号：US10897856

    申请日：2004-07-23

    申请人： Marina Brockway ,  Donald Hopper ,  Gerrard M. Carlson ,  Veerichetty Kadhiresan ,  Kenneth Beck

    发明人： Marina Brockway ,  Donald Hopper ,  Gerrard M. Carlson ,  Veerichetty Kadhiresan ,  Kenneth Beck

    IPC分类号： A61B5/0402

    CPC分类号： A61B5/087 ,  A61B5/02405 ,  A61B5/053 ,  A61B5/4878 ,  A61N1/3627 ,  A61N1/36521

    摘要： A system receives signals indicative of cardiopulmonary conditions sensed by a plurality of sensors and provides for monitoring and automated differential diagnosis of the cardiopulmonary conditions based on the signals. Cardiogenic pulmonary edema is detected based on one or more signals sensed by implantable sensors. If the cardiogenic pulmonary edema is not detected, obstructive pulmonary disease and restrictive pulmonary disease are each detected based on a forced vital capacity (FVC) parameter and a forced expiratory volume (FEV) parameter measured from a respiratory signal sensed by an implantable or non-implantable sensor. In one embodiment, an implantable medical device senses signals indicative of the cardiopulmonary conditions, and an external system detects the cardiopulmonary conditions based on these signals by executing an automatic detection algorithm.

    摘要翻译： 系统接收指示由多个传感器感测到的心肺疾病的信号，并且基于该信号提供对心肺病状态的监测和自动鉴别诊断。 基于由可植入传感器感测到的一个或多个信号来检测心源性肺水肿。 如果没有检测到心源性肺水肿，则基于由可植入或非可行性肺动脉血流检测的呼吸信号测量的强制肺活量（FVC）参数和强制呼气量（FEV）参数，每个都检测到阻塞性肺疾病和限制性肺部疾病， 植入式传感器。 在一个实施例中，可植入医疗装置感测指示心肺病的信号，外部系统通过执行自动检测算法基于这些信号来检测心肺病。

    Logging daily average metabolic activity using a motion sensor
    5.
    发明申请
    Logging daily average metabolic activity using a motion sensor 有权
    使用运动传感器记录日常平均代谢活动

    公开(公告)号：US20090069720A1

    公开(公告)日：2009-03-12

    申请号：US11900596

    申请日：2007-09-12

    申请人： Kenneth Beck ,  Ramesh Wariar ,  Chie Kawahara ,  Gerrard M. Carlson

    发明人： Kenneth Beck ,  Ramesh Wariar ,  Chie Kawahara ,  Gerrard M. Carlson

    IPC分类号： A61B5/00

    CPC分类号： A61B5/1118 ,  A61B5/0002 ,  A61B5/4866

    摘要： An implantable activity detector can detect metabolic stress levels, which can be normalized, such as to identify times of activities such as walking and running or to identify trends such as a decrease in metabolic activity. The data can be derived from different sources such as an accelerometer and pedometer. This data can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with other congestive heart failure (CHF) indications. The alert can notify the patient or a caregiver, such as via remote monitoring. Metabolic activity data from one or more of the activity detectors can be used to establish a model of metabolic stress, to which further activity data can be compared for identifying periods of increased or decreased metabolic stress.

    摘要翻译： 可植入活动检测器可以检测代谢应激水平，其可以被归一化，例如识别诸如步行和跑步的活动的时间，或者识别诸如代谢活动降低的趋势。 数据可以来自不同的来源，例如加速度计和计步器。 该数据可以与独立指定的阈值进行比较，例如触发警报或响应治疗，或显示一个或多个趋势。 信息也可以与其他充血性心力衰竭（CHF）指征结合使用。 该警报可以通过远程监视来通知病人或看护者。 来自一个或多个活性检测器的代谢活动数据可以用于建立代谢应激模型，进一步的活动数据可以被比较以识别增加或减少的代谢应激的时期。

    Logging daily average metabolic activity using a motion sensor
    10.
    发明授权
    Logging daily average metabolic activity using a motion sensor 有权

    公开(公告)号：US09254100B2

    公开(公告)日：2016-02-09

    申请号：US11900596

    申请日：2007-09-12

    申请人： Kenneth Beck ,  Ramesh Wariar ,  Chie Kawahara ,  Gerrard M. Carlson

    发明人： Kenneth Beck ,  Ramesh Wariar ,  Chie Kawahara ,  Gerrard M. Carlson

    IPC分类号： A61B5/117 ,  A61B5/103 ,  A61B5/11 ,  A61B5/00

    CPC分类号： A61B5/1118 ,  A61B5/0002 ,  A61B5/4866

    摘要： An implantable activity detector can detect metabolic stress levels, which can be normalized, such as to identify times of activities such as walking and running or to identify trends such as a decrease in metabolic activity. The data can be derived from different sources such as an accelerometer and pedometer. This data can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with other congestive heart failure (CHF) indications. The alert can notify the patient or a caregiver, such as via remote monitoring. Metabolic activity data from one or more of the activity detectors can be used to establish a model of metabolic stress, to which further activity data can be compared for identifying periods of increased or decreased metabolic stress.