公开(公告)号：US06647134B1

公开(公告)日：2003-11-11

申请号：US09595282

申请日：2000-06-15

申请人： Kiaran P. McGee ,  Joel Felmlee ,  Richard Ehman ,  Armando Manduca

发明人： Kiaran P. McGee ,  Joel Felmlee ,  Richard Ehman ,  Armando Manduca

IPC分类号： G06K900

CPC分类号： G01R33/56509 ,  G01R33/4822 ,  G01R33/5635 ,  G01R33/56572 ,  G01R33/5673 ,  G06T1/20 ,  G06T5/006 ,  G06T11/006 ,  G06T2211/412 ,  G06T2211/424

摘要： An MRA image is corrected for motion artifacts using an iterative, autocorrection process in which corrections are tried and the quality of the resulting reconstructed image is measured. Corrections are made to the acquired three-dimensional data while the metric which measures image quality is applied to a two-dimensional projection image.

摘要翻译： 使用迭代自动校正过程来校正运动伪影的MRA图像，其中尝试校正并测量所得到的重建图像的质量。 对所获取的三维数据进行校正，同时将测量图像质量的度量应用于二维投影图像。

公开(公告)号：US09562960B2

公开(公告)日：2017-02-07

申请号：US12935968

申请日：2009-04-03

申请人： Arunark Kolipaka ,  Armando Manduca ,  Kiaran P. Mcgee ,  Richard L. Ehman ,  Kevin J. Glaser

发明人： Arunark Kolipaka ,  Armando Manduca ,  Kiaran P. Mcgee ,  Richard L. Ehman ,  Kevin J. Glaser

IPC分类号： A61B5/055 ,  G01R33/563 ,  A61B5/00

CPC分类号： G01R33/56358 ,  A61B5/0051 ,  A61B5/416

摘要： A method for magnetic resonance elastography (“MRE”) is described, in which an MRE inversion that accounts for waves propagating in a finite, bounded media is employed. A vibratory motion is induced in a subject and MRE is performed to measure one or more components of the resulting displacement produced in the subject. This displacement data is subsequently filtered to provide a more accurate and computationally efficient method of inversion. Wave equations based on the geometry of the bounded media are then utilized to calculate the material properties of the subject. Such a method allows for the performance of MRE on tissues such as the heart, eye, bladder, and prostate with more accurate results.

摘要翻译： 描述了一种用于磁共振弹性成像（“MRE”）的方法，其中采用考虑在有限的有界介质中传播的波的MRE反演。 在受试者中诱发振动，并执行MRE以测量在受试者中产生的所得到的位移的一个或多个成分。 随后对该位移数据进行滤波以提供更精确和计算上有效的反演方法。 然后利用基于有界介质的几何形状的波动方程来计算受试者的材料性质。 这种方法允许在更精确的结果上在诸如心脏，眼睛，膀胱和前列腺的组织上表现MRE。

公开(公告)号：US06307369B1

公开(公告)日：2001-10-23

申请号：US09614893

申请日：2000-07-12

申请人： Joel P. Felmlee ,  Kiaran P. McGee ,  Richard L. Ehman ,  Armando Manduca

发明人： Joel P. Felmlee ,  Kiaran P. McGee ,  Richard L. Ehman ,  Armando Manduca

IPC分类号： G01V300

CPC分类号： G01R33/56509 ,  G01R33/4822 ,  G01R33/5673

摘要： A three-dimensional image data set is acquired with an MRI system and autocorrected to reduce artifacts caused by subject motion during image acquisition. Correction for motion along one or two axes is performed by selecting a 2D slice of data and autocorrecting it to produce phase corrections that are then made to the entire 3D image data set. This may be repeated by autocorrecting an additional 2D slice perpendicular to the first 2D slice to produce phase corrections for the 3D image data set for motion along the third axis.

摘要翻译： 利用MRI系统获取三维图像数据集并进行自动校正，以减少在图像采集期间由被摄体运动引起的伪像。 通过选择2D切片数据并对其进行自动校正来执行沿着一个或两个轴的运动的校正，以产生对整个3D图像数据集进行相位校正。 这可以通过自动校正垂直于第一2D切片的附加2D切片来重复，以产生用于沿着第三轴的运动的3D图像数据集的相位校正。

公开(公告)号：US08952693B2

公开(公告)日：2015-02-10

申请号：US13453653

申请日：2012-04-23

申请人： David S Lake ,  Kiaran P McGee ,  Armando Manduca ,  Yogesh K Mariappan ,  Richard L Ehman

发明人： David S Lake ,  Kiaran P McGee ,  Armando Manduca ,  Yogesh K Mariappan ,  Richard L Ehman

IPC分类号： G01R33/563

CPC分类号： G01R33/56358

摘要： A method for calculating a mechanical property of a material using a magnetic resonance imaging (“MRI”) system is provided. The method is particularly robust to image data having low signal-to-noise ratio (“SNR”). An MRI system is used to acquire magnetic resonance elastography (“MRE”) data from a subject containing the material. Exemplary materials include lung tissue. Images are reconstructed from the MRE data and used to produce a wave image from which a spatial frequency spectrum is produced. A principal frequency of the spatial frequency spectrum is produced and used to calculate a mechanical property of the material. For example, shear stiffness may be calculated.

摘要翻译： 提供了使用磁共振成像（“MRI”）系统计算材料的机械特性的方法。 该方法对具有低信噪比（“SNR”）的图像数据特别鲁棒​​。 MRI系统用于从包含材料的受试者获取磁共振弹性成像（“MRE”）数据。 示例性材料包括肺组织。 从MRE数据重建图像，并用于产生从其产生空间频谱的波形图像。 产生空间频谱的主频率并用于计算材料的机械性能。 例如，可以计算剪切刚度。

公开(公告)号：US06184682B2

公开(公告)日：2001-02-06

申请号：US09290817

申请日：1999-04-13

申请人： Richard L. Ehman ,  Joel P. Felmlee ,  Armando Manduca ,  Kiaran P. McGee

发明人： Richard L. Ehman ,  Joel P. Felmlee ,  Armando Manduca ,  Kiaran P. McGee

IPC分类号： G01V300

CPC分类号： G06T5/003 ,  G06T5/10 ,  G06T5/50 ,  G06T2207/10016 ,  G06T2207/10088 ,  G06T2207/20056 ,  G06T2207/30004 ,  G06T2207/30168

摘要： Navigator echo signals are acquired during an MRI scan in which image data is acquired. The navigator echo signals are used to estimate an initial correction of the acquired image data for patient motion during the scan. The initially corrected image data is then autocorrected in an iterative process which measures image quality and makes further corrections to the image data until the measured image quality is within tolerance.

摘要翻译： 在获取图像数据的MRI扫描期间获取导航回波信号。 导航回波信号用于估计在扫描期间所获取的图像数据的患者运动的初始校正。 然后在迭代过程中自动校正最初校正的图像数据，该迭代过程测量图像质量并进一步校正图像数据，直到测量的图像质量在容差内。

公开(公告)号：US20120268128A1

公开(公告)日：2012-10-25

申请号：US13453653

申请日：2012-04-23

申请人： David S. Lake ,  Kiaran P. McGee ,  Armando Manduca ,  Yogesh K. Mariappan ,  Richard L. Ehman

发明人： David S. Lake ,  Kiaran P. McGee ,  Armando Manduca ,  Yogesh K. Mariappan ,  Richard L. Ehman

IPC分类号： G01R33/483 ,  G01R33/341

CPC分类号： G01R33/56358

摘要： A method for calculating a mechanical property of a material using a magnetic resonance imaging (“MRI”) system is provided. The method is particularly robust to image data having low signal-to-noise ratio (“SNR”). An MRI system is used to acquire magnetic resonance elastography (“MRE”) data from a subject containing the material. Exemplary materials include lung tissue. Images are reconstructed from the MRE data and used to produce a wave image from which a spatial frequency spectrum is produced. A principal frequency of the spatial frequency spectrum is produced and used to calculate a mechanical property of the material. For example, shear stiffness may be calculated.

摘要翻译： 提供了使用磁共振成像（MRI）系统计算材料的机械特性的方法。 该方法对具有低信噪比（SNR）的图像数据特别鲁棒​​。 MRI系统用于从包含材料的受试者获取磁共振弹性成像（MRE）数据。 示例性材料包括肺组织。 从MRE数据重建图像，并用于产生从其产生空间频谱的波形图像。 产生空间频谱的主频率并用于计算材料的机械性能。 例如，可以计算剪切刚度。

公开(公告)号：US20110092798A1

公开(公告)日：2011-04-21

申请号：US12935968

申请日：2009-04-03

申请人： Arunark Kolipaka ,  Armando Manduca ,  Kiaran P. Mcgee ,  Richard L. Ehman ,  Kevin J. Glaser

发明人： Arunark Kolipaka ,  Armando Manduca ,  Kiaran P. Mcgee ,  Richard L. Ehman ,  Kevin J. Glaser

IPC分类号： A61B5/055

CPC分类号： G01R33/56358 ,  A61B5/0051 ,  A61B5/416

摘要： A method for magnetic resonance elastography (“MRE”) is described, in which an MRE inversion that accounts for waves propagating in a finite, bounded media is employed. A vibratory motion is induced in a subject and MRE is performed to measure one or more components of the resulting displacement produced in the subject. This displacement data is subsequently filtered to provide a more accurate and computationally efficient method of inversion. Wave equations based on the geometry of the bounded media are then utilized to calculate the material properties of the subject. Such a method allows for the performance of MRE on tissues such as the heart, eye, bladder, and prostate with more accurate results.

摘要翻译： 描述了一种用于磁共振弹性成像（“MRE”）的方法，其中采用考虑在有限的有界介质中传播的波的MRE反演。 在受试者中诱发振动，并执行MRE以测量在受试者中产生的所得到的位移的一个或多个成分。 随后对该位移数据进行滤波以提供更精确和计算上有效的反演方法。 然后利用基于有界介质的几何形状的波动方程来计算受试者的材料性质。 这种方法允许在更精确的结果上在诸如心脏，眼睛，膀胱和前列腺的组织上表现MRE。

公开(公告)号：US06469506B1

公开(公告)日：2002-10-22

申请号：US09595272

申请日：2000-06-15

申请人： Joel P. Felmlee ,  Kiaran P. McGee ,  Richard L. Ehman ,  Armando Manduca

发明人： Joel P. Felmlee ,  Kiaran P. McGee ,  Richard L. Ehman ,  Armando Manduca

IPC分类号： G01V300

CPC分类号： G01R33/3415

摘要： An MRI image acquired with a phase-array coil is corrected for motion artifacts using an iterative, autocorrection process in which corrections are tried and the quality of the resulting reconstructed image is measured. In one embodiment autocorrections are calculated for the data acquired with one coil element and the same corrections are made to data acquired with the other coil elements. In another embodiment autocorrections are calculated separately for the data acquired with each coil element. In either embodiment, the separate corrected images are combined to form the output image.

摘要翻译： 用相位阵列线圈获取的MRI图像使用迭代自动校正过程来校正运动伪像，其中尝试校正并测量所得到的重建图像的质量。 在一个实施例中，对于用一个线圈元件获取的数据计算自动校正，并且对与其它线圈元件获取的数据进行相同的校正。 在另一个实施例中，为每个线圈元件采集的数据分别计算自动校正。 在任一实施例中，组合分离的校正图像以形成输出图像。

公开(公告)号：US20160253825A1

公开(公告)日：2016-09-01

申请号：US15032938

申请日：2014-10-22

申请人： Joshua D. TRZASKO ,  Armando MANDUCA

发明人： Joshua D. Trzasko ,  Armando Manduca

IPC分类号： G06T11/00 ,  A61B5/00 ,  G06T7/00

CPC分类号： G06T11/003 ,  A61B5/743 ,  G01R33/5608 ,  G06T7/0012 ,  G06T7/0016 ,  G06T2207/10076 ,  G06T2207/10088 ,  G06T2207/10092

摘要： A system and method for estimating a physiological parameter from data acquired with a medical imaging system includes acquiring data with the medical imaging system. A physiological parameter is estimated from the acquired data using an iterative estimation in which a model of the medical imaging system is decoupled from a physics-based model of the acquired data.

摘要翻译： 从用医学成像系统获取的数据估计生理参数的系统和方法包括用医学成像系统获取数据。 使用迭代估计从所获取的数据估计生理参数，其中医学成像系统的模型与所获取的数据的基于物理的模型解耦。

公开(公告)号：US20150309136A1

公开(公告)日：2015-10-29

申请号：US14694621

申请日：2015-04-23

申请人： Yunhong Shu ,  Armando Manduca ,  Joshua D. Trzasko ,  Matthew A. Bernstein

发明人： Yunhong Shu ,  Armando Manduca ,  Joshua D. Trzasko ,  Matthew A. Bernstein

IPC分类号： G01R33/48 ,  G01R33/36 ,  G01R33/561 ,  G01R33/385 ,  G01R33/56

CPC分类号： G01R33/4826 ,  G01R33/5611

摘要： Systems and methods for efficiently generating MR images are provided. The method comprises acquiring k-space MR data, reconstructing an MR image from the k-space MR data, and generating the MR image. The MR image is reconstructed using an alternative-direction-method-of-multiplier (ADMM) strategy that decomposes an optimization problem into subproblems, and at least one of the subproblems is further decomposed into small problems. The further decomposition is based on Woodbury matrix identity and uses a diagonal preconditioner based on non-Toeplitz models.

摘要翻译： 提供了有效产生MR图像的系统和方法。 该方法包括获取k空间MR数据，从k空间MR数据重建MR图像，以及生成MR图像。 使用将优化问题分解为子问题的替代方向乘法器（ADMM）策略重构MR图像，并且至少一个子问题进一步分解为小问题。 进一步分解是基于Woodbury矩阵身份，并使用基于非Toeplitz模型的对角预处理器。