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    Process for the production of L-arginine by fermentation
    1.
    发明授权
    Process for the production of L-arginine by fermentation 失效
    通过发酵生产L-精氨酸的方法

    公开(公告)号：US4086137A

    公开(公告)日：1978-04-25

    申请号：US766630

    申请日：1977-02-08

    申请人： Kiyoshi Nakayama ,  Kazumi Araki ,  Hajime Yoshida

    发明人： Kiyoshi Nakayama ,  Kazumi Araki ,  Hajime Yoshida

    IPC分类号： C12P13/10 ,  C12R1/07 ,  C12D13/06

    CPC分类号： C12P13/10 ,  Y10S435/839

    摘要： L-arginine is produced by fermentation of a microorganism belonging to the genus Bacillus capable of producing L-arginine and having a nutritional requirement for at least one compound of the group consisting of methionine, histidine, threonine, proline, isoleucine, lysine, adenine, guanine and uracil or its precursor. L-arginine is accumulated in the culture liquor and may be recovered therefrom.

    摘要翻译： L-精氨酸通过发酵能产生L-精氨酸的芽孢杆菌属的微生物产生，并且对至少一种由甲硫氨酸，组氨酸，苏氨酸，脯氨酸，异亮氨酸，赖氨酸，腺嘌呤， 鸟嘌呤和尿嘧啶或其前体。 L-精氨酸在培养液中积聚并可从其中回收。

    Process for the production of L-lysine by fermentation
    2.
    发明授权
    Process for the production of L-lysine by fermentation 失效
    通过发酵生产L-赖氨酸的方法

    公开(公告)号：US4169763A

    公开(公告)日：1979-10-02

    申请号：US814621

    申请日：1977-07-11

    申请人： Kiyoshi Nakayama ,  Kazumi Araki ,  Yoshitake Tanaka

    发明人： Kiyoshi Nakayama ,  Kazumi Araki ,  Yoshitake Tanaka

    IPC分类号： C12P13/08 ,  C12R1/15 ,  C12D13/06

    CPC分类号： C12P13/08 ,  Y10S435/843

    摘要： A process for producing L-lysine by fermentation includes the steps of culturing a strain belonging to the genus Corynebacterium having both an ability to produce L-lysine and a resistance to at least one member selected from the group consisting of aspartic acid analogs and sulfa drugs in a nutrient medium, forming and accumulating L-lysine in the resulting culture liquor and thereafter recovering the L-lysine therefrom.

    摘要翻译： 通过发酵生产L-赖氨酸的方法包括以下步骤：培养属于棒状杆菌属的菌株，其具有产生L-赖氨酸的能力和对至少一种选自天冬氨酸类似物和磺胺类药物的成员 在营养培养基中，在所得培养液中形成和积聚L-赖氨酸，然后从中回收L-赖氨酸。

    Process for production of L-serine
    3.
    发明授权
    Process for production of L-serine 失效
    生产L-丝氨酸的方法

    公开(公告)号：US4183786A

    公开(公告)日：1980-01-15

    申请号：US855328

    申请日：1977-11-28

    申请人： Kiyoshi Nakayama ,  Kazumi Araki ,  Yoshitake Tanaka

    发明人： Kiyoshi Nakayama ,  Kazumi Araki ,  Yoshitake Tanaka

    IPC分类号： C12P13/06 ,  C12D13/06

    CPC分类号： C12P13/06 ,  Y10S435/872

    摘要： A process for converting glycine to L-serine is effected by the use of an aqueous medium containing glycine and microbial cells of a mutant belonging to the genus Nocardia. The mutant is capable of converting glycine to L-serine and has no or lowered ability to decompose L-serine and/or a resistance to at least one metabolic antagonist selected from those of glycine, serine, methionine, glutamine, histidine, leucine, isoleucine, valine, purine, pyrimidine or folic acid. The L-serine is accumulated in the aqueous medium and is recovered therefrom.

    摘要翻译： 将甘氨酸转化为L-丝氨酸的方法通过使用含有甘氨酸的水性培养基和属于诺卡氏菌属的突变体的微生物细胞来实现。 突变体能够将甘氨酸转化为L-丝氨酸，并且没有或降低分解L-丝氨酸的能力和/或对至少一种选自甘氨酸，丝氨酸，甲硫氨酸，谷氨酰胺，组氨酸，亮氨酸，异亮氨酸的代谢拮抗剂的抗性 ，缬氨酸，嘌呤，嘧啶或叶酸。 L-丝氨酸在水性介质中积聚并从中回收。

    Process for producing L-histidine by fermentation
    5.
    发明授权
    Process for producing L-histidine by fermentation 失效
    通过发酵生产L-组氨酸的方法

    公开(公告)号：US4495283A

    公开(公告)日：1985-01-22

    申请号：US482892

    申请日：1983-04-07

    申请人： Kazumi Araki ,  Tetsuro Kuga

    发明人： Kazumi Araki ,  Tetsuro Kuga

    IPC分类号： C12P13/24 ,  C12R1/13 ,  C12R1/15 ,  C12N1/20 ,  C12N15/00

    CPC分类号： C12P13/24 ,  Y10S435/84 ,  Y10S435/843

    摘要： L-histidine is produced by culturing, in a nutrient medium, an L-histidine producing mutant microorganism belonging to the genus Corynebacterium or Brevibacterium. The mutant is resistant to growth inhibition by an RNA polymerase inhibitor or requires adenine. L-histidine is accumulated in the culture liquor and is recovered therefrom.

    摘要翻译： 通过在营养培养基中培养属于棒状杆菌属或短杆菌属的L-组氨酸生产突变体微生物来产生L-组氨酸。 突变体对RNA聚合酶抑制剂的生长抑制具有抗性，或需要腺嘌呤。 L-组氨酸在培养液中积聚并从中回收。