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    Apparatus For Fluorescence Diagnosis
    2.
    发明申请
    Apparatus For Fluorescence Diagnosis 审中-公开
    荧光诊断仪

    公开(公告)号：US20100261965A1

    公开(公告)日：2010-10-14

    申请号：US12755144

    申请日：2010-04-06

    申请人： Gerd Beck ,  Andre Ehrhardt ,  Klaus-Martin Irion

    发明人： Gerd Beck ,  Andre Ehrhardt ,  Klaus-Martin Irion

    IPC分类号： A61B1/06 ,  G01J1/58

    CPC分类号： A61B5/0071 ,  A61B1/043 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/0084

    摘要： An apparatus for fluorescence diagnosis comprises an illumination system for illuminating a target area. The illumination system has a light source designed for generating white light and an illumination path. The apparatus further comprises an observation system for observing the target area, which has an observation path. The illumination system has a first illumination mode, in which an illumination spectral filter is arranged in the illumination path, which filter is transmitting in an excitation spectral range and substantially non-transmitting in the spectral range on the long-wavelength side outside of the excitation spectral range, and said illumination system has a second illumination mode, in which the illumination spectral filter is not arranged in the illumination path. An observation spectral filter is arranged in the observation path in the first illumination mode and in the second illumination mode, which filter is substantially non-transmitting in the excitation spectral range and transmitting in the spectral range on the long-wavelength side outside of the excitation spectral range. The observation spectral filter additionally is transmitting in the spectral range on the short-wavelength side outside of the excitation spectral range.

    摘要翻译： 用于荧光诊断的装置包括用于照射目标区域的照明系统。 照明系统具有用于产生白光和照明路径的光源。 该装置还包括用于观察具有观察路径的目标区域的观察系统。 照明系统具有第一照明模式，其中照明光谱滤波器布置在照明路径中，该滤光器在激发光谱范围内发射，并且在激发外侧的长波长侧的光谱范围内基本上不发射 光谱范围，并且所述照明系统具有第二照明模式，其中照明光谱滤光器未布置在照明路径中。 在第一照明模式和第二照明模式下，观察光谱滤波器被布置在观察路径中，该滤波器在激励光谱范围内基本上不发射，并且在激发外侧的长波长侧的光谱范围内发射 光谱范围 观测光谱滤波器另外在激发光谱范围外的短波长侧的光谱范围内进行发射。

    Device For Fluorescence Diagnosis
    3.
    发明申请
    Device For Fluorescence Diagnosis 审中-公开
    荧光诊断装置

    公开(公告)号：US20120248333A1

    公开(公告)日：2012-10-04

    申请号：US13430174

    申请日：2012-03-26

    申请人： Johannes Fallert ,  Peter Schwarz ,  Werner Goebel ,  Andre Ehrhardt ,  Klaus-Martin Irion

    发明人： Johannes Fallert ,  Peter Schwarz ,  Werner Goebel ,  Andre Ehrhardt ,  Klaus-Martin Irion

    IPC分类号： G01N21/64

    CPC分类号： G01N21/6456 ,  A61B1/00186 ,  A61B1/0638 ,  A61B1/0646 ,  G01N2021/6471

    摘要： A diagnosis device having an illumination system configured to produce white light along an illumination path, an observation system for observing the target region in a white-light and fluorescence mode, the observation system having an observation path having at least one first image sensor for receiving a white-light image and at least one second image sensor for receiving a fluorescence image, an observation spectral filter in the observation path are configured such that light in the spectral range of the fluorescence can be fed to the second image sensor while light in the spectral ranges outside of the fluorescence is blocked. An illumination spectral filter is arranged in the illumination path and having a characteristic of the observation spectral filter such that the target region is illuminated with the whole spectral range of the white light with the exception of the spectral range of the fluorescence to be observed.

    摘要翻译： 一种具有照明系统的诊断装置，被配置为沿着照明路径产生白光，观察系统用于以白光和荧光模式观察所述目标区域，所述观察系统具有观察路径，所述观察路径具有至少一个用于接收的第一图像传感器 白光图像和用于接收荧光图像的至少一个第二图像传感器，观察路径中的观察光谱滤波器被配置为使得荧光的光谱范围内的光可以被馈送到第二图像传感器，同时在 荧光外的光谱范围被阻断。 照明光谱滤光器布置在照明路径中，并且具有观察光谱滤波器的特性，使得除了要观察的荧光的光谱范围之外，白色光的整个光谱范围被照射目标区域。

    Apparatus For Fluorescence Diagnosis
    5.
    发明申请
    Apparatus For Fluorescence Diagnosis 审中-公开
    荧光诊断仪

    公开(公告)号：US20100259656A1

    公开(公告)日：2010-10-14

    申请号：US12756567

    申请日：2010-04-08

    申请人： Klaus-Martin Irion ,  Andre Ehrhardt ,  Peter Solleder

    发明人： Klaus-Martin Irion ,  Andre Ehrhardt ,  Peter Solleder

    IPC分类号： H04N5/335 ,  G02B21/06

    CPC分类号： A61B5/0071 ,  A61B1/00186 ,  A61B1/043 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0669 ,  A61B5/0084

    摘要： An apparatus for fluorescence diagnosis comprises an illumination system for illuminating a target area. The observation system has an observation instrument and a camera. The illumination system can be switched between at least two illumination modes. The observation system has an optical arrangement having at least one optical element that selectively can be introduced into the observation beam path or can be removed therefrom in order to switch the optical properties of the observation system between at least two observation modes. The optical arrangement of the observation system has a motor drive for introducing the at least one optical element into the observation beam path and for removing said element therefrom, and there is a control unit which is connected to the illumination system and to the observation system and which controls the motor drive as a function of the set illumination mode of the illumination system.

    摘要翻译： 用于荧光诊断的装置包括用于照射目标区域的照明系统。 观察系统具有观察仪器和摄像机。 照明系统可以在至少两个照明模式之间切换。 观察系统具有光学装置，其具有选择性地可以被引入观察光束路径中的至少一个光学元件，或者可以从其中去除，以便在至少两个观察模式之间切换观察系统的光学特性。 观察系统的光学布置具有用于将至少一个光学元件引入观察光束路径并从中去除所述元件的电机驱动器，并且存在连接到照明系统和观察系统的控制单元， 其根据照明系统的设定照明模式控制电动机驱动。

    Test apparatus for an optical investigation system
    8.
    发明授权
    Test apparatus for an optical investigation system 有权
    光学调查系统的测试装置

    公开(公告)号：US08586946B2

    公开(公告)日：2013-11-19

    申请号：US12969891

    申请日：2010-12-16

    申请人： Gerd Beck ,  Bernhard Gloeggler ,  Andre Ehrhardt

    发明人： Gerd Beck ,  Bernhard Gloeggler ,  Andre Ehrhardt

    IPC分类号： G01J1/58

    CPC分类号： A61B1/00057 ,  A61B1/043 ,  A61B5/0059 ,  A61B5/1495 ,  A61B2560/0233 ,  G01N21/276

    摘要： A test apparatus for an optical investigation system, with an imaging device and a light source for optical investigation of an object in remitted light and/or fluorescent light includes a housing with a hollow space and an aperture for inserting a distal end of the imaging device into the hollow space, a reference surface with predetermined optical properties in the hollow space, at least either for remission of illuminating light directed onto the reference surface or for emission of fluorescent light, and a positioning device to hold the imaging device of the distal end of the imaging device at a predetermined position in relation to the reference surface.

    摘要翻译： 一种用于光学调查系统的测试装置，具有成像装置和用于光学研究的光源，用于放射光和/或荧光灯中的物体包括具有中空空间的壳体和用于插入成像装置的远端的孔 在中空空间中具有在中空空间中具有预定光学特性的参考表面，至少用于缓和被引导到参考表面上的照明光或用于发射荧光，以及定位装置来保持远端的成像装置 在相对于参考表面的预定位置处的成像装置。

    Confocal microendoscope comprising optical fibres with a tapering diameter
    9.
    发明申请
    Confocal microendoscope comprising optical fibres with a tapering diameter 审中-公开
    共焦显微镜，包括具有锥形直径的光纤

    公开(公告)号：US20070053204A1

    公开(公告)日：2007-03-08

    申请号：US10573141

    申请日：2004-09-10

    申请人： Ingo Krohne ,  Andre Ehrhardt ,  Klaus Irion ,  Herbert Stepp

    发明人： Ingo Krohne ,  Andre Ehrhardt ,  Klaus Irion ,  Herbert Stepp

    IPC分类号： A61B3/00 ,  A61B1/06 ,  G03B29/00 ,  G03B15/02 ,  G02B6/06 ,  F21V5/00

    CPC分类号： A61B5/0068 ,  A61B5/0084 ,  G02B21/0028 ,  G02B23/2461

    摘要： The invention relates to a confocal microendoscope, in which the diameter of optical fibres at the proximal end (8) of an optical fibre bundle (9) is greater than at the distal end (15). This permits the efficiency of coupling the light of a light source to be increased, without reducing the resolution of the microendoscope. In addition, the proximal ends (8) of the optical fibres (10) are arranged in a grid, for example, by means of a fibre receiving unit (11) that holds the individual optical fibres. A microlens unit (13) can also be provided, said unit allocating a microlens (14) to each optical fibre end.

    摘要翻译： 本发明涉及一种共焦显微镜，其中光纤束（9）的近端（8）处的光纤的直径大于远端（15）处的光纤直径。 这允许在不降低微内镜的分辨率的情况下增加耦合光源的光的效率。 此外，光纤（10）的近端（8）例如通过保持各个光纤的光纤接收单元（11）布置成格栅。 还可以设置微透镜单元（13），所述单元向每个光纤端分配微透镜（14）。