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公开(公告)号:US09072791B2
公开(公告)日:2015-07-07
申请号:US13121852
申请日:2009-09-30
IPC分类号: A01N43/04 , A61K31/715 , A01N43/90 , A61K31/519 , A61K47/48 , A61K9/00 , A61K9/08 , A61K45/06
CPC分类号: A61K47/4823 , A61K9/0019 , A61K9/08 , A61K45/06 , A61K47/61
摘要: A crosslinking reaction and a reaction for reducing molecular weight that take place in a hyaluronic acid-methotrexate conjugate upon irradiation with light are suppressed to improve the photostability of the conjugate. Specifically, a substance having a quenching effect and/or a radical scaveng effect is added to a pharmaceutical composition containing the hyaluronic acid-methotrexate conjugate.
摘要翻译: 抑制交联反应和用于降低在光照射时在透明质酸 - 甲氨蝶呤偶联物中发生的分子量的反应,以提高缀合物的光稳定性。 具体地说,将具有淬灭效果和/或自由基清除作用的物质加入到含有透明质酸 - 甲氨蝶呤缀合物的药物组合物中。
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公开(公告)号:US20110245276A1
公开(公告)日:2011-10-06
申请号:US13121852
申请日:2009-09-30
IPC分类号: A61K31/519 , A61P19/02 , A61B17/00
CPC分类号: A61K47/4823 , A61K9/0019 , A61K9/08 , A61K45/06 , A61K47/61
摘要: A crosslinking reaction and a reaction for reducing molecular weight that take place in a hyaluronic acid-methotrexate conjugate upon irradiation with light are suppressed to improve the photostability of the conjugate. Specifically, a substance having a quenching effect and/or a radical scaveng effect is added to a pharmaceutical composition containing the hyaluronic acid-methotrexate conjugate.
摘要翻译: 抑制交联反应和用于降低在光照射时在透明质酸 - 甲氨蝶呤偶联物中发生的分子量的反应,以提高缀合物的光稳定性。 具体地说,将具有淬灭效果和/或自由基清除作用的物质加入到含有透明质酸 - 甲氨蝶呤缀合物的药物组合物中。
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公开(公告)号:US5844454A
公开(公告)日:1998-12-01
申请号:US823206
申请日:1997-03-24
申请人: Shoji Ono , Masaki Shibata
发明人: Shoji Ono , Masaki Shibata
IPC分类号: H01P1/205
CPC分类号: H01P1/2056
摘要: A dielectric filter for a high frequency band includes a plurality of resonators formed by boring a plurality of through holes between the oppositely disposed end surfaces of a dielectric block in parallel with each other and arranging internal conductors on the inner peripheral surfaces of the respective through holes and an external conductor formed on a substantial portion of the outer peripheral surface of the dielectric block. A non-conductive region is formed on the short-circuit end surface and extends in parallel with the direction connecting the resonators, thereby the filter can be controlled satisfactorily for coupling the dielectric coaxial resonators and have a reduced height.
摘要翻译: 用于高频带的介质滤波器包括多个谐振器,该谐振器通过在介质块的相对设置的端面彼此平行地钻孔多个通孔而形成,并且将内部导体布置在各个通孔的内周面上 以及形成在介质块的外周面的主要部分上的外部导体。 在短路端面上形成非导电区域,并且与连接谐振器的方向平行地延伸,从而可以令人满意地控制滤波器以耦合介质同轴谐振器并具有减小的高度。
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公开(公告)号:US06801167B2
公开(公告)日:2004-10-05
申请号:US10396691
申请日:2003-03-26
申请人: Masaki Shibata
发明人: Masaki Shibata
IPC分类号: H01Q138
CPC分类号: H01Q1/526 , H01Q9/0407 , H01Q9/045
摘要: A dielectric antenna includes a plate-shaped dielectric substrate, a radiation electrode provided on a first main surface of the dielectric substrate so as to cover the first main surface except for a peripheral portion thereof, and a ground electrode formed on the entirety of a second main surface of the dielectric substrate. A feed electrode extends through the dielectric substrate from the first main surface to the second main surface. A feed point of the feed electrode is electrically connected to the radiation electrode. A plurality of through-hole electrodes providing an electrical shield are formed in a peripheral portion of the dielectric substrate so as to surround the radiation electrode, the through-hole electrodes being connected to the ground electrode. Alternatively, instead of the through-hole electrodes, the dielectric antenna may include a shield electrode formed on a side surface of the dielectric substrate and connected to the ground electrode.
摘要翻译: 电介质天线包括板状电介质基板,设置在电介质基板的第一主面上以覆盖第一主表面以外的辐射电极,除了其周边部分之外,还包括形成在第二主体的整体上的接地电极 电介质基片的主表面。 馈电电极从第一主表面延伸穿过电介质基片到第二主表面。 馈电电极的馈电点电连接到辐射电极。 在电介质基板的周边部分形成多个设有电屏蔽的通孔电极,以便包围辐射电极,通孔电极连接到接地电极。 或者,代替通孔电极,电介质天线可以包括形成在电介质基板的侧表面上并连接到接地电极的屏蔽电极。
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公开(公告)号:US4224345A
公开(公告)日:1980-09-23
申请号:US951719
申请日:1978-10-16
申请人: Shichigoro Tezuka , Masaki Shibata
发明人: Shichigoro Tezuka , Masaki Shibata
摘要: A chewing gum base consisting of about 18 to 40% by weight of rubber and about 82 to 60% by weight of basic materials of a chewing gum and a combination of this chewing gum base with ordinary chewing gum additives and fatty matter.
摘要翻译: 一种口香糖胶基,其由约18至40重量%的橡胶和约82至60重量%的口香糖的基础材料和该口香糖胶基与普通口香糖添加剂和脂肪物质的组合组成。
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公开(公告)号:US5124156A
公开(公告)日:1992-06-23
申请号:US570956
申请日:1990-08-20
申请人: Masaki Shibata , Toshio Takiguchi , Yoji Saeki , Hajime Nunome
发明人: Masaki Shibata , Toshio Takiguchi , Yoji Saeki , Hajime Nunome
CPC分类号: A61K9/0058 , A61K38/47
摘要: A chewing gum for preventing pyorrhea alveolaris contains 0.2 to 3.0% of lysozyme of egg white and 0.05 to 0.5% of mace extract.
摘要翻译: 用于预防脓肿肺泡的口香糖含有0.2〜3.0%的蛋清溶菌酶和0.05〜0.5%的精华提取物。
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公开(公告)号:US4514423A
公开(公告)日:1985-04-30
申请号:US576761
申请日:1984-02-01
IPC分类号: A23G3/20 , A23G4/00 , A23G4/04 , A23G4/06 , A23G4/08 , A23G4/20 , A23G9/24 , A23G9/32 , A23G9/48 , A23G3/30
CPC分类号: A23G9/48 , A23G3/2007 , A23G4/043 , A23G4/046 , A23G4/06 , A23G4/066 , A23G4/08 , A23G4/20 , A23G9/24
摘要: A bubble gum having strengthened membrane forming properties wherein the base contains vinyl acetate resin filler emulsifiers, flavor color and fragrance and includes 2.5% to 15% by weight of a fat or oil ingredient, not less than 15% by weight of rubber and 15 to 17 parts by weight wax, said base being free of ester gum.
摘要翻译: 具有增强的膜形成性质的泡泡糖,其中所述基体含有乙酸乙烯酯树脂填料乳化剂,风味颜色和香料,并且包含2.5至15重量%的脂肪或油成分,不小于15重量%的橡胶和15至 17重量份的蜡,所述的碱不含酯胶。
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公开(公告)号:US4399153A
公开(公告)日:1983-08-16
申请号:US296903
申请日:1981-08-27
IPC分类号: A23G4/00 , A23G4/04 , A23G4/06 , A23G4/18 , A23G9/26 , A23G9/32 , A23G9/50 , A23G3/30 , A23G9/04 , A23G9/24
摘要: A frozen dessert such as ice cream or ices with chewing gum supporting the frozen dessert is provided. The stick chewing gum is prepared using anhydrous glucose as a sweetener without use of sucrose and subjected to two separate aging steps, especially to a second aging at -10.degree. to -5.degree. C.
摘要翻译: 提供了一种冷冻的甜点,例如冰淇淋或含有支持冷冻甜点的口香糖的冰糖。 使用无水葡萄糖作为甜味剂而不使用蔗糖制备棒状口香糖,并进行两个分离的老化步骤,特别是在-10℃至-5℃下进行第二次老化。
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公开(公告)号:US08420668B2
公开(公告)日:2013-04-16
申请号:US13131422
申请日:2009-11-27
申请人: Kazuo Hattori , Takehiro Okada , Osamu Kondoh , Toshiyuki Tsukaguchi , Masaki Shibata , Satoshi Tanida
发明人: Kazuo Hattori , Takehiro Okada , Osamu Kondoh , Toshiyuki Tsukaguchi , Masaki Shibata , Satoshi Tanida
IPC分类号: C07D413/04 , A61K31/47
CPC分类号: C07F9/65583 , A61K9/0019
摘要: The present invention provides a compound of the formula (I) or a pharmaceutically acceptable salt thereof:
摘要翻译: 本发明提供式(I)化合物或其药学上可接受的盐:
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公开(公告)号:US20110282062A1
公开(公告)日:2011-11-17
申请号:US13131422
申请日:2009-11-27
申请人: Kazuo Hattori , Takehiro Okada , Osamu Kondoh , Toshiyuki Tsukaguchi , Masaki Shibata , Satoshi Tanida
发明人: Kazuo Hattori , Takehiro Okada , Osamu Kondoh , Toshiyuki Tsukaguchi , Masaki Shibata , Satoshi Tanida
IPC分类号: C07F9/06
CPC分类号: C07F9/65583 , A61K9/0019
摘要: The present invention provides a compound of the formula (I) or a pharmaceutically acceptable salt thereof:
摘要翻译: 本发明提供式(I)化合物或其药学上可接受的盐:
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